Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii(toxin)
Location 1733190..1734709 Replicon chromosome
Accession NZ_CP016432
Organism Prosthecochloris sp. CIB 2401 strain CIB2401

Toxin (Protein)


Gene name rlegT Uniprot ID A0A1B1Q3Q0
Locus tag Ptc2401_RS08190 Protein ID WP_068867628.1
Coordinates 1733786..1734709 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A5C4RX98
Locus tag Ptc2401_RS08185 Protein ID WP_068867627.1
Coordinates 1733190..1733789 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Ptc2401_RS08155 1729404..1730420 + 1017 WP_204208429.1 DUF1016 family protein -
Ptc2401_RS08160 1730417..1730908 + 492 WP_204208347.1 restriction endonuclease subunit S -
Ptc2401_RS08165 1730873..1731874 - 1002 WP_204208431.1 IS3 family transposase -
Ptc2401_RS08170 1731913..1732221 - 309 WP_068866996.1 transposase -
Ptc2401_RS08175 1732291..1732899 + 609 Protein_1611 type I restriction endonuclease subunit R -
Ptc2401_RS11450 1732918..1733058 + 141 WP_156767503.1 hypothetical protein -
Ptc2401_RS08185 1733190..1733789 + 600 WP_068867627.1 hypothetical protein Antitoxin
Ptc2401_RS08190 1733786..1734709 + 924 WP_068867628.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
Ptc2401_RS11455 1734719..1734877 - 159 WP_156767504.1 hypothetical protein -
Ptc2401_RS11460 1734998..1735174 - 177 WP_156767505.1 hypothetical protein -
Ptc2401_RS08195 1735161..1738220 - 3060 Protein_1617 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1738216..1739712 1496


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(39-275)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 35086.37 Da        Isoelectric Point: 6.1665

>T64626 WP_068867628.1 NZ_CP016432:1733786-1734709 [Prosthecochloris sp. CIB 2401]
MKKKPVKDTSASVRARLLNLARSTGRDFQELTVRYTVERFLSRLAESEHRERFILKGAMLYIPWKLDNKRTTMDLDLLGF
GSPDMENLKTVFQEICDTAIEDDGLIFNKDTVTVTQIREESVYDGVRIIVRVHLGAMPIRLQVDVGFGDQIVPAPQSAEF
PALLAEHGPIIRSYSPETVIAEKFNAMIVLGMANSRMKDYFDIWMVSRNFTIEADVLREAIRQTFEKRHTELPLDEPIAL
SEEFFSNVSKQSQWKGFVRKQRRLNSAPTLEEIIEVLRTFLLPVVFEIGADALAVKTWSPDSGWSSK

Download         Length: 924 bp

>T64626 NZ_CP016432:1733786-1734709 [Prosthecochloris sp. CIB 2401]
ATGAAAAAGAAACCAGTGAAAGACACAAGCGCCTCGGTTCGAGCTCGACTGTTGAATCTTGCCAGGTCGACAGGAAGAGA
TTTTCAGGAATTGACAGTTCGATACACTGTGGAGCGGTTCCTTTCAAGATTGGCTGAGAGTGAGCACCGTGAGCGATTCA
TTCTCAAAGGTGCTATGCTGTATATACCATGGAAGCTTGATAACAAGCGGACAACAATGGACCTTGACCTGCTGGGATTT
GGCAGTCCTGATATGGAAAATCTGAAGACCGTATTTCAGGAGATCTGCGATACCGCAATCGAAGATGATGGACTCATTTT
CAATAAGGACACTGTAACCGTTACCCAGATCCGTGAAGAGTCAGTTTATGACGGTGTTCGGATTATTGTGCGTGTGCATC
TTGGGGCTATGCCAATACGGCTGCAAGTGGATGTAGGCTTTGGAGATCAAATTGTACCAGCACCTCAATCAGCAGAGTTT
CCGGCGCTTCTAGCCGAACACGGTCCAATCATTCGCTCTTACTCTCCTGAAACGGTGATAGCTGAAAAGTTCAACGCCAT
GATCGTTCTGGGAATGGCAAACAGTCGGATGAAGGATTACTTCGATATTTGGATGGTAAGCCGAAATTTCACAATCGAAG
CGGATGTACTGAGGGAAGCAATCAGGCAAACATTCGAGAAGAGGCATACGGAATTGCCTCTGGATGAGCCCATTGCTCTC
AGTGAGGAATTTTTCAGTAATGTTTCCAAGCAGAGTCAGTGGAAAGGTTTTGTCAGGAAGCAAAGAAGGCTGAATTCAGC
GCCCACCCTTGAAGAAATTATTGAAGTTCTCAGAACTTTTCTGTTGCCGGTGGTATTTGAAATCGGCGCAGACGCATTGG
CGGTTAAGACATGGTCTCCGGATAGCGGCTGGTCTTCCAAATAG

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22396.15 Da        Isoelectric Point: 8.5865

>AT64626 WP_068867627.1 NZ_CP016432:1733190-1733789 [Prosthecochloris sp. CIB 2401]
MKTTKDKILDVAGKQSVFRAGDIPDVRKPQTELCRMVADGELIRVGRGLYSLPDAEVGENHSLVEAVKLYHGGVICLMSA
LYFHRIGTQLPYETWIMRQNRNVAPVKGSPVRFVYCTGDAFSFGVEKHMIEGTEVSIYSPAKTVADCFKYRNKIGLDVAL
EALQEGWKAKLFTMNELYAAVKVCRVQKIIQPYMEMLVQ

Download         Length: 600 bp

>AT64626 NZ_CP016432:1733190-1733789 [Prosthecochloris sp. CIB 2401]
ATGAAAACCACAAAAGACAAAATACTGGATGTTGCAGGAAAGCAGTCGGTGTTCCGAGCCGGAGATATTCCTGATGTCCG
GAAACCACAGACTGAACTGTGTCGTATGGTTGCCGACGGCGAGCTTATCCGTGTTGGACGCGGGCTGTATTCACTCCCAG
ACGCAGAGGTTGGCGAGAACCATTCGCTCGTCGAAGCGGTGAAACTCTACCATGGAGGAGTGATATGCCTGATGTCAGCA
CTCTATTTTCATCGGATTGGCACCCAGCTTCCTTATGAAACATGGATTATGCGTCAGAATCGAAATGTGGCACCGGTCAA
AGGTTCACCGGTTCGTTTTGTCTATTGTACGGGTGACGCGTTTTCTTTTGGCGTAGAAAAACACATGATTGAAGGAACTG
AAGTCAGTATTTACAGCCCGGCAAAAACGGTTGCCGACTGCTTTAAATACCGTAATAAAATCGGACTGGATGTTGCCCTT
GAAGCCCTACAGGAGGGTTGGAAGGCAAAGCTTTTCACCATGAATGAGCTATATGCTGCGGTGAAAGTTTGTCGTGTACA
GAAAATTATCCAGCCCTATATGGAGATGCTTGTTCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B1Q3Q0

Antitoxin

Source ID Structure
AlphaFold DB A0A5C4RX98

References