Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 560226..560694 Replicon chromosome
Accession NZ_CP016432
Organism Prosthecochloris sp. CIB 2401 strain CIB2401

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag Ptc2401_RS11120 Protein ID WP_083188109.1
Coordinates 560226..560486 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID A0A5C4S0N8
Locus tag Ptc2401_RS02550 Protein ID WP_041702602.1
Coordinates 560470..560694 (-) Length 75 a.a.

Genomic Context

Ptc2401_RS02525Ptc2401_RS02530Ptc2401_RS02535Ptc2401_RS02555Ptc2401_RS02540Ptc2401_RS02545Ptc2401_RS11120Ptc2401_RS02550Ptc2401_RS11125Ptc2401_RS02560Ptc2401_RS02565Ptc2401_RS11565
Location: 555690..556442 (753 bp)
Type: Others
Protein ID: WP_068866443.1
Location: 556446..557006 (561 bp)
Type: Others
Protein ID: WP_068866445.1
Location: 557057..557593 (537 bp)
Type: Others
Protein ID: WP_068866447.1
Location: 561261..562796 (1536 bp)
Type: Others
Protein ID: WP_068866450.1
Location: 557660..559060 (1401 bp)
Type: Others
Protein ID: WP_068868178.1
Location: 559108..559911 (804 bp)
Type: Others
Protein ID: WP_068866449.1
Location: 560226..560486 (261 bp)
Type: Toxin
Protein ID: WP_083188109.1
Location: 560470..560694 (225 bp)
Type: Antitoxin
Protein ID: WP_041702602.1
Location: 563230..563512 (283 bp)
Type: Others
Protein ID: Protein_495
Location: 563488..563751 (264 bp)
Type: Others
Protein ID: WP_068866452.1
Location: 564151..564486 (336 bp)
Type: Others
Protein ID: Protein_497
Location: 564378..565274 (897 bp)
Type: Others
Protein ID: Protein_498
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
Ptc2401_RS02525555690..556442+753WP_068866443.1YebC/PmpR family DNA-binding transcriptional regulator-
Ptc2401_RS02530556446..557006+561WP_068866445.1crossover junction endodeoxyribonuclease RuvC-
Ptc2401_RS02535557057..557593+537WP_068866447.1CDP-alcohol phosphatidyltransferase family protein-
Ptc2401_RS02540557660..559060-1401WP_068868178.1bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/3-hydroxyacyl-ACP dehydratase-
Ptc2401_RS02545559108..559911-804WP_068866449.1inositol monophosphatase-
Ptc2401_RS11120560226..560486-261WP_083188109.1type II toxin-antitoxin system RelE/ParE family toxinToxin
Ptc2401_RS02550560470..560694-225WP_041702602.1ribbon-helix-helix protein, CopG familyAntitoxin
Ptc2401_RS02555561261..562796+1536WP_068866450.1Fic family protein-
Ptc2401_RS11125563230..563512-283Protein_495Txe/YoeB family addiction module toxin-
Ptc2401_RS02560563488..563751-264WP_068866452.1hypothetical protein-
Ptc2401_RS02565564151..564486-336Protein_497FAD:protein FMN transferase-
Ptc2401_RS11565564378..565274-897Protein_498integron integrase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--457375..695810238435


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-85)

Antitoxin

Relaxosome protein TraY

(8-48)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10070.71 Da        Isoelectric Point: 10.6191

>T64623 WP_083188109.1 NZ_CP016432:c560486-560226 [Prosthecochloris sp. CIB 2401]
MVWTIEFAATAENELSKLDKSAAKRILKFLKERVATDPRSSGKALRGDYARLWRYRIGDYRVICEIRDQTVSVLVVRIGH
RKEVYR

Download         Length: 261 bp

>T64623 NZ_CP016432:c560486-560226 [Prosthecochloris sp. CIB 2401]
TTGGTCTGGACGATTGAGTTTGCCGCGACAGCGGAAAATGAATTGTCCAAGTTGGATAAATCTGCGGCAAAGCGGATTCT
CAAATTTCTGAAAGAGCGCGTTGCCACTGATCCCCGCTCATCGGGCAAGGCGTTGCGTGGCGATTATGCCAGACTCTGGC
GGTATCGCATCGGTGATTATCGGGTGATTTGCGAAATCCGGGATCAGACCGTTTCGGTTCTTGTCGTTCGGATCGGGCAT
CGGAAAGAGGTTTATCGGTAG

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8594.77 Da        Isoelectric Point: 4.8605

>AT64623 WP_041702602.1 NZ_CP016432:c560694-560470 [Prosthecochloris sp. CIB 2401]
MIGIRIPKSVGQRLDNLAKRTGRTKTWYVREAIMAHLDDLEDIYLAEQVLERVRRGEEAVSDIDEVERRLGLDD

Download         Length: 225 bp

>AT64623 NZ_CP016432:c560694-560470 [Prosthecochloris sp. CIB 2401]
ATGATCGGAATTCGTATTCCGAAGAGCGTGGGTCAACGGCTGGATAACCTTGCAAAAAGAACTGGCCGAACCAAGACCTG
GTATGTTCGCGAGGCGATAATGGCGCACCTCGATGATCTTGAAGACATTTATCTGGCAGAACAGGTTCTCGAACGCGTGA
GGCGTGGAGAAGAGGCTGTGTCCGATATAGATGAAGTGGAGCGTCGTCTTGGTCTGGACGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A5C4S0N8

References