Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 263669..264312 Replicon plasmid pCVM44454
Accession NZ_CP016413
Organism Salmonella enterica subsp. enterica serovar Infantis strain CVM44454

Toxin (Protein)


Gene name vagD Uniprot ID B1LRW4
Locus tag BAR51_RS25355 Protein ID WP_001044768.1
Coordinates 263896..264312 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID D2WFK3
Locus tag BAR51_RS25350 Protein ID WP_001261287.1
Coordinates 263669..263899 (+) Length 77 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BAR51_RS25335 259780..260868 + 1089 WP_000952231.1 hypothetical protein -
BAR51_RS25340 260870..261739 + 870 WP_000253407.1 hypothetical protein -
BAR51_RS25345 261796..263361 - 1566 WP_000741348.1 AAA family ATPase -
BAR51_RS26160 263554..263691 + 138 WP_077248527.1 toxin-antitoxin system, antitoxin component, AbrB family protein -
BAR51_RS25350 263669..263899 + 231 WP_001261287.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
BAR51_RS25355 263896..264312 + 417 WP_001044768.1 type II toxin-antitoxin system VapC family toxin Toxin
BAR51_RS25360 264474..266612 - 2139 WP_000350635.1 AAA family ATPase -
BAR51_RS25365 266966..267223 + 258 WP_000343085.1 hypothetical protein -
BAR51_RS25370 267223..267813 + 591 WP_000194575.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..316160 316160


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-123)

Antitoxin

(8-55)


Sequences


Toxin        


Download         Length: 139 a.a.        Molecular weight: 17834.22 Da        Isoelectric Point: 12.9398

>T64615 WP_001044768.1 NZ_CP016413:263896-264312 [Salmonella enterica subsp. enterica serovar Infantis]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 417 bp

>T64615 NZ_CP016413:263896-264312 [Salmonella enterica subsp. enterica serovar Infantis]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 9887.42 Da        Isoelectric Point: 12.6808

>AT64615 WP_001261287.1 NZ_CP016413:263669-263899 [Salmonella enterica subsp. enterica serovar Infantis]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 231 bp

>AT64615 NZ_CP016413:263669-263899 [Salmonella enterica subsp. enterica serovar Infantis]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A606Q844


Antitoxin

Source ID Structure
AlphaFold DB A0A7U9QFC4

References