Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 967884..968472 Replicon chromosome
Accession NZ_CP016397
Organism Legionella clemsonensis strain CDC-D5610

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag clem_RS04170 Protein ID WP_094090469.1
Coordinates 968125..968472 (+) Length 116 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag clem_RS04165 Protein ID WP_094090468.1
Coordinates 967884..968135 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
clem_RS04145 963301..964587 + 1287 WP_094090464.1 replication-associated recombination protein A -
clem_RS04150 964702..965808 + 1107 WP_094090465.1 type III polyketide synthase -
clem_RS04155 965945..966670 - 726 WP_094090466.1 hypothetical protein -
clem_RS04160 966826..967494 - 669 WP_094090467.1 DedA family protein -
clem_RS04165 967884..968135 + 252 WP_094090468.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
clem_RS04170 968125..968472 + 348 WP_094090469.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
clem_RS04175 968503..968634 + 132 WP_157698120.1 helix-turn-helix domain-containing protein -
clem_RS04180 968678..968944 + 267 WP_094089730.1 hypothetical protein -
clem_RS04185 968978..969427 + 450 WP_094089729.1 hypothetical protein -
clem_RS04190 969858..970856 + 999 WP_094090471.1 ATP-binding protein -
clem_RS04195 970882..972204 + 1323 WP_094090472.1 sigma-54 dependent transcriptional regulator -
clem_RS04200 972388..972702 + 315 WP_094092266.1 flagellar hook-basal body complex protein FliE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-70)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 13207.17 Da        Isoelectric Point: 9.9642

>T64554 WP_094090469.1 NZ_CP016397:968125-968472 [Legionella clemsonensis]
MIYELHFHPLALKEWKKLGKNLQEEFKKVLKGPLENPHVASAGLRGALKNCYKIKLRQSGYRLVYQVNDNKLIVTVIAVG
KRNKNVVYDDADNRQEDNKLDKSSWQNLAPSATDE

Download         Length: 348 bp

>T64554 NZ_CP016397:968125-968472 [Legionella clemsonensis]
ATGATTTATGAGCTTCATTTTCATCCTTTAGCTCTAAAAGAATGGAAAAAGCTGGGGAAAAACCTTCAAGAAGAGTTCAA
GAAAGTGTTAAAAGGCCCTTTAGAAAATCCACATGTGGCTTCGGCTGGCTTAAGAGGAGCTTTGAAAAATTGCTATAAAA
TAAAATTACGTCAATCTGGTTATCGTTTGGTGTATCAGGTTAATGATAATAAATTGATCGTAACCGTCATAGCGGTGGGG
AAAAGAAACAAAAATGTTGTCTATGATGATGCGGATAACCGACAAGAAGACAATAAATTAGATAAATCATCTTGGCAGAA
TCTCGCGCCAAGTGCGACAGATGAATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9341.79 Da        Isoelectric Point: 5.6492

>AT64554 WP_094090468.1 NZ_CP016397:967884-968135 [Legionella clemsonensis]
MQTLFATQVASISELKKNPTKLINDAHGKPVAILNHNTAAAYLIPVETFEKLMDLVDENELYKIVEQRLSARFTSIKVNI
DDL

Download         Length: 252 bp

>AT64554 NZ_CP016397:967884-968135 [Legionella clemsonensis]
ATGCAAACTTTATTTGCCACACAAGTAGCGAGTATTAGTGAATTAAAAAAGAACCCCACTAAGCTCATTAATGATGCTCA
TGGGAAACCTGTTGCTATTCTTAACCACAATACAGCGGCAGCATATCTAATTCCTGTTGAAACATTTGAAAAACTAATGG
ATTTGGTTGATGAGAATGAACTATATAAAATAGTAGAGCAGCGTTTGTCTGCACGGTTTACCTCAATAAAGGTAAATATT
GATGATTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References