Detailed information of TA system TA064549

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yxiD-yxxD/-
• Location: 3554889..3555677
• Replicon: chromosome
• Accession: NZ_CP016395
• Organism: Bacillus velezensis strain M75

Toxin (Protein)

• Gene name: yxiD
• Uniprot ID: -
• Locus tag: BBJ33_RS20320
• Protein ID: WP_079891856.1
• Coordinates: 3555336..3555677 (-)
• Length: 114 a.a.

Antitoxin (Protein)

• Gene name: yxxD
• Uniprot ID: -
• Locus tag: BBJ33_RS17290
• Protein ID: WP_014305975.1
• Coordinates: 3554889..3555326 (-)
• Length: 146 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BBJ33_RS17255	3550417..3550953	+	537	WP_003151296.1	chromate resistance efflux protein ChrA	-
BBJ33_RS17260	3550980..3551198	-	219	WP_003151295.1	hypothetical protein	-
BBJ33_RS17265	3551195..3551740	-	546	WP_003151294.1	flavodoxin family protein	-
BBJ33_RS17270	3551863..3552744	+	882	WP_003151293.1	LysR family transcriptional regulator	-
BBJ33_RS17275	3552830..3553546	-	717	WP_069473605.1	endonuclease V	-
BBJ33_RS17280	3553586..3554086	-	501	WP_015387596.1	hypothetical protein	-
BBJ33_RS17285	3554278..3554718	-	441	WP_025649364.1	SMI1/KNR4 family protein	-
BBJ33_RS17290	3554889..3555326	-	438	WP_014305975.1	SMI1/KNR4 family protein	Antitoxin
BBJ33_RS20320	3555336..3555677	-	342	WP_079891856.1	HNH endonuclease	Toxin
BBJ33_RS20325	3556296..3556634	-	339	Protein_3390	transposase	-
BBJ33_RS20010	3557273..3557738	-	466	Protein_3391	DUF2004 domain-containing protein	-
BBJ33_RS20100	3557740..3558322	-	583	Protein_3392	HNH endonuclease	-
BBJ33_RS17310	3558435..3558740	-	306	WP_003151282.1	hypothetical protein	-
BBJ33_RS17315	3558757..3560502	-	1746	WP_046341443.1	ribonuclease YeeF family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 13224.74 Da
• Isoelectric Point: 9.6942

>T64549 WP_079891856.1 NZ_CP016395:c3555677-3555336 [Bacillus velezensis]
IKEALRNNNYEKLTPKETAKHRSKFTSSLKDRLIAEWEEKTNQKWPRYTEEVFDKHGEVARSIGQPYDAHHIIENNFGGP
HEWWNIHPAKYPDEHQAGIHGKGAPSGKLFPRR

Nucleotide

• Length: 342 bp

>T64549 NZ_CP016395:c3555677-3555336 [Bacillus velezensis]
ATAAAAGAAGCTTTAAGAAATAATAACTATGAGAAATTAACACCAAAAGAAACAGCTAAGCATAGGAGCAAATTCACATC
AAGTTTGAAAGATAGATTGATTGCAGAATGGGAAGAAAAAACCAATCAAAAGTGGCCTAGATATACAGAAGAGGTTTTTG
ATAAGCATGGAGAAGTTGCCCGAAGTATTGGTCAACCGTACGATGCCCATCATATCATAGAGAACAACTTTGGTGGCCCT
CACGAATGGTGGAATATTCATCCGGCAAAATATCCGGATGAACACCAAGCGGGTATACATGGAAAGGGAGCACCATCAGG
AAAACTTTTTCCAAGGAGGTAA

Antitoxin

Protein

• Length: 146 a.a.
• Molecular weight: 17050.05 Da
• Isoelectric Point: 3.8675

>AT64549 WP_014305975.1 NZ_CP016395:c3555326-3554889 [Bacillus velezensis]
MAEFEFINHLENKTYKVPEEDILKAEQRMNVDIPNDLKQLYLEVGYGFIKGESDNAINRILGPGAVADIRLREGIFEFDP
DLDELYDDENKLIFFEVNEGVYISIDLRLANNPIFYFDTQIAESLEDFFKKFLNDNEYYIDLIED

Nucleotide

• Length: 438 bp

>AT64549 NZ_CP016395:c3555326-3554889 [Bacillus velezensis]
ATGGCTGAATTTGAATTTATAAATCATTTAGAAAATAAAACATATAAGGTACCTGAAGAGGATATATTAAAAGCTGAACA
AAGAATGAACGTAGATATTCCAAATGATTTAAAACAATTATATTTAGAAGTCGGTTATGGTTTTATTAAAGGTGAAAGTG
ATAATGCAATTAATAGGATATTGGGGCCAGGGGCAGTAGCCGACATTAGACTAAGAGAAGGAATTTTTGAGTTTGACCCA
GATTTAGATGAACTTTATGATGATGAAAATAAACTTATTTTTTTTGAAGTAAACGAGGGTGTTTATATTTCTATAGATTT
ACGATTGGCAAATAATCCAATATTTTATTTTGACACTCAAATAGCTGAATCTTTAGAGGATTTTTTTAAAAAGTTCCTCA
ATGATAATGAATATTATATTGATTTAATTGAGGATTAG