Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/RelB(antitoxin) |
Location | 278925..279537 | Replicon | chromosome |
Accession | NZ_CP016391 | ||
Organism | Streptococcus agalactiae strain FWL1402 |
Toxin (Protein)
Gene name | parE | Uniprot ID | A0A8G2N8L3 |
Locus tag | A9256_RS01605 | Protein ID | WP_000384860.1 |
Coordinates | 278925..279260 (-) | Length | 112 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | Q8E7D2 |
Locus tag | A9256_RS01610 | Protein ID | WP_000259017.1 |
Coordinates | 279250..279537 (-) | Length | 96 a.a. |
Genomic Context
Location: 274123..274764 (642 bp)
Type: Others
Protein ID: WP_000591144.1
Type: Others
Protein ID: WP_000591144.1
Location: 275064..275939 (876 bp)
Type: Others
Protein ID: WP_000421240.1
Type: Others
Protein ID: WP_000421240.1
Location: 275975..276409 (435 bp)
Type: Others
Protein ID: WP_001220479.1
Type: Others
Protein ID: WP_001220479.1
Location: 276726..277982 (1257 bp)
Type: Others
Protein ID: WP_000122836.1
Type: Others
Protein ID: WP_000122836.1
Location: 278150..278620 (471 bp)
Type: Others
Protein ID: WP_000130119.1
Type: Others
Protein ID: WP_000130119.1
Location: 280044..280334 (291 bp)
Type: Others
Protein ID: WP_000078283.1
Type: Others
Protein ID: WP_000078283.1
Location: 280436..280804 (369 bp)
Type: Others
Protein ID: WP_001882138.1
Type: Others
Protein ID: WP_001882138.1
Location: 280842..281402 (561 bp)
Type: Others
Protein ID: WP_001865562.1
Type: Others
Protein ID: WP_001865562.1
Location: 281375..282055 (681 bp)
Type: Others
Protein ID: WP_001865565.1
Type: Others
Protein ID: WP_001865565.1
Location: 282040..282426 (387 bp)
Type: Others
Protein ID: WP_000259069.1
Type: Others
Protein ID: WP_000259069.1
Location: 282460..282741 (282 bp)
Type: Others
Protein ID: WP_017647916.1
Type: Others
Protein ID: WP_017647916.1
Location: 283584..284444 (861 bp)
Type: Others
Protein ID: WP_000477654.1
Type: Others
Protein ID: WP_000477654.1
Location: 278925..279260 (336 bp)
Type: Toxin
Protein ID: WP_000384860.1
Type: Toxin
Protein ID: WP_000384860.1
Location: 279250..279537 (288 bp)
Type: Antitoxin
Protein ID: WP_000259017.1
Type: Antitoxin
Protein ID: WP_000259017.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
A9256_RS01575 | 274123..274764 | + | 642 | WP_000591144.1 | hypothetical protein | - |
A9256_RS01585 | 275064..275939 | + | 876 | WP_000421240.1 | hypothetical protein | - |
A9256_RS01590 | 275975..276409 | + | 435 | WP_001220479.1 | hypothetical protein | - |
A9256_RS01595 | 276726..277982 | + | 1257 | WP_000122836.1 | plasmid recombination protein | - |
A9256_RS01600 | 278150..278620 | + | 471 | WP_000130119.1 | hypothetical protein | - |
A9256_RS01605 | 278925..279260 | - | 336 | WP_000384860.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
A9256_RS01610 | 279250..279537 | - | 288 | WP_000259017.1 | hypothetical protein | Antitoxin |
A9256_RS01615 | 280044..280334 | + | 291 | WP_000078283.1 | WXG100 family type VII secretion target | - |
A9256_RS01620 | 280436..280804 | + | 369 | WP_001882138.1 | hypothetical protein | - |
A9256_RS01625 | 280842..281402 | + | 561 | WP_001865562.1 | hypothetical protein | - |
A9256_RS01630 | 281375..282055 | + | 681 | WP_001865565.1 | hypothetical protein | - |
A9256_RS01635 | 282040..282426 | + | 387 | WP_000259069.1 | hypothetical protein | - |
A9256_RS01640 | 282460..282741 | + | 282 | WP_017647916.1 | hypothetical protein | - |
A9256_RS01655 | 283584..284444 | + | 861 | WP_000477654.1 | Rgg/GadR/MutR family transcriptional regulator | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 112 a.a. Molecular weight: 13227.87 Da Isoelectric Point: 4.5348
>T64546 WP_000384860.1 NZ_CP016391:c279260-278925 [Streptococcus agalactiae]
MDYKKYQIIYAPDVLEKLKEIRDYISQNYSSTSGQRKMEQIINDIEKLEVFPEVGFDADEKYGSEISNYHSTRGYTLSKD
YIVLYHIEEEENSVVIDYLLPTRSDYMKLFK
MDYKKYQIIYAPDVLEKLKEIRDYISQNYSSTSGQRKMEQIINDIEKLEVFPEVGFDADEKYGSEISNYHSTRGYTLSKD
YIVLYHIEEEENSVVIDYLLPTRSDYMKLFK
Download Length: 336 bp
>T64546 NZ_CP016391:c279260-278925 [Streptococcus agalactiae]
TTGGACTATAAGAAATATCAGATTATCTATGCTCCTGATGTTTTAGAGAAGCTAAAAGAAATTCGTGATTATATTTCCCA
AAACTATTCCTCAACATCAGGTCAGCGTAAAATGGAGCAAATCATTAATGACATAGAAAAACTTGAAGTTTTCCCAGAAG
TTGGTTTTGATGCCGATGAAAAATATGGTTCAGAAATCAGCAATTATCACAGTACTAGAGGTTACACCTTAAGTAAAGAT
TATATTGTCCTATACCATATCGAAGAGGAAGAGAATAGCGTTGTCATTGATTACTTGCTTCCTACTCGAAGCGACTATAT
GAAATTGTTTAAATAG
TTGGACTATAAGAAATATCAGATTATCTATGCTCCTGATGTTTTAGAGAAGCTAAAAGAAATTCGTGATTATATTTCCCA
AAACTATTCCTCAACATCAGGTCAGCGTAAAATGGAGCAAATCATTAATGACATAGAAAAACTTGAAGTTTTCCCAGAAG
TTGGTTTTGATGCCGATGAAAAATATGGTTCAGAAATCAGCAATTATCACAGTACTAGAGGTTACACCTTAAGTAAAGAT
TATATTGTCCTATACCATATCGAAGAGGAAGAGAATAGCGTTGTCATTGATTACTTGCTTCCTACTCGAAGCGACTATAT
GAAATTGTTTAAATAG
Antitoxin
Download Length: 96 a.a. Molecular weight: 10906.50 Da Isoelectric Point: 4.7271
>AT64546 WP_000259017.1 NZ_CP016391:c279537-279250 [Streptococcus agalactiae]
MVTVEKNRAVTFQANKELVSEAMTVLNKKNLTLSSALRLFLQNVVVTNEVDLLTEEELEKEKLFKQFQAEISKNIEDVRQ
GKFYTSEEVRAELGL
MVTVEKNRAVTFQANKELVSEAMTVLNKKNLTLSSALRLFLQNVVVTNEVDLLTEEELEKEKLFKQFQAEISKNIEDVRQ
GKFYTSEEVRAELGL
Download Length: 288 bp
>AT64546 NZ_CP016391:c279537-279250 [Streptococcus agalactiae]
ATGGTTACAGTAGAAAAAAATAGAGCTGTCACATTCCAAGCTAACAAAGAATTGGTAAGCGAAGCAATGACAGTATTAAA
CAAAAAAAATTTAACCTTATCATCTGCTTTAAGATTATTCCTACAAAATGTCGTTGTCACAAACGAGGTTGACTTATTGA
CGGAAGAGGAGTTAGAGAAAGAAAAACTTTTCAAGCAATTTCAAGCCGAAATCAGCAAAAATATTGAGGATGTTCGTCAA
GGGAAGTTTTATACCTCTGAAGAAGTGAGGGCTGAACTTGGACTATAA
ATGGTTACAGTAGAAAAAAATAGAGCTGTCACATTCCAAGCTAACAAAGAATTGGTAAGCGAAGCAATGACAGTATTAAA
CAAAAAAAATTTAACCTTATCATCTGCTTTAAGATTATTCCTACAAAATGTCGTTGTCACAAACGAGGTTGACTTATTGA
CGGAAGAGGAGTTAGAGAAAGAAAAACTTTTCAAGCAATTTCAAGCCGAAATCAGCAAAAATATTGAGGATGTTCGTCAA
GGGAAGTTTTATACCTCTGAAGAAGTGAGGGCTGAACTTGGACTATAA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
No matching records found |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A076Z4V6 |