Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parDE/RelB(antitoxin)
Location 278925..279537 Replicon chromosome
Accession NZ_CP016391
Organism Streptococcus agalactiae strain FWL1402

Toxin (Protein)


Gene name parE Uniprot ID A0A8G2N8L3
Locus tag A9256_RS01605 Protein ID WP_000384860.1
Coordinates 278925..279260 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID Q8E7D2
Locus tag A9256_RS01610 Protein ID WP_000259017.1
Coordinates 279250..279537 (-) Length 96 a.a.

Genomic Context


A9256_RS01575A9256_RS01585A9256_RS01590A9256_RS01595A9256_RS01600A9256_RS01615A9256_RS01620A9256_RS01625A9256_RS01630A9256_RS01635A9256_RS01640A9256_RS01655A9256_RS01605A9256_RS01610
Location: 274123..274764 (642 bp)
Type: Others
Protein ID: WP_000591144.1
Location: 275064..275939 (876 bp)
Type: Others
Protein ID: WP_000421240.1
Location: 275975..276409 (435 bp)
Type: Others
Protein ID: WP_001220479.1
Location: 276726..277982 (1257 bp)
Type: Others
Protein ID: WP_000122836.1
Location: 278150..278620 (471 bp)
Type: Others
Protein ID: WP_000130119.1
Location: 280044..280334 (291 bp)
Type: Others
Protein ID: WP_000078283.1
Location: 280436..280804 (369 bp)
Type: Others
Protein ID: WP_001882138.1
Location: 280842..281402 (561 bp)
Type: Others
Protein ID: WP_001865562.1
Location: 281375..282055 (681 bp)
Type: Others
Protein ID: WP_001865565.1
Location: 282040..282426 (387 bp)
Type: Others
Protein ID: WP_000259069.1
Location: 282460..282741 (282 bp)
Type: Others
Protein ID: WP_017647916.1
Location: 283584..284444 (861 bp)
Type: Others
Protein ID: WP_000477654.1
Location: 278925..279260 (336 bp)
Type: Toxin
Protein ID: WP_000384860.1
Location: 279250..279537 (288 bp)
Type: Antitoxin
Protein ID: WP_000259017.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
A9256_RS01575274123..274764+642WP_000591144.1hypothetical protein-
A9256_RS01585275064..275939+876WP_000421240.1hypothetical protein-
A9256_RS01590275975..276409+435WP_001220479.1hypothetical protein-
A9256_RS01595276726..277982+1257WP_000122836.1plasmid recombination protein-
A9256_RS01600278150..278620+471WP_000130119.1hypothetical protein-
A9256_RS01605278925..279260-336WP_000384860.1type II toxin-antitoxin system RelE/ParE family toxinToxin
A9256_RS01610279250..279537-288WP_000259017.1hypothetical proteinAntitoxin
A9256_RS01615280044..280334+291WP_000078283.1WXG100 family type VII secretion target-
A9256_RS01620280436..280804+369WP_001882138.1hypothetical protein-
A9256_RS01625280842..281402+561WP_001865562.1hypothetical protein-
A9256_RS01630281375..282055+681WP_001865565.1hypothetical protein-
A9256_RS01635282040..282426+387WP_000259069.1hypothetical protein-
A9256_RS01640282460..282741+282WP_017647916.1hypothetical protein-
A9256_RS01655283584..284444+861WP_000477654.1Rgg/GadR/MutR family transcriptional regulator-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(8-106)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 112 a.a.        Molecular weight: 13227.87 Da        Isoelectric Point: 4.5348

>T64546 WP_000384860.1 NZ_CP016391:c279260-278925 [Streptococcus agalactiae]
MDYKKYQIIYAPDVLEKLKEIRDYISQNYSSTSGQRKMEQIINDIEKLEVFPEVGFDADEKYGSEISNYHSTRGYTLSKD
YIVLYHIEEEENSVVIDYLLPTRSDYMKLFK

Download         Length: 336 bp

>T64546 NZ_CP016391:c279260-278925 [Streptococcus agalactiae]
TTGGACTATAAGAAATATCAGATTATCTATGCTCCTGATGTTTTAGAGAAGCTAAAAGAAATTCGTGATTATATTTCCCA
AAACTATTCCTCAACATCAGGTCAGCGTAAAATGGAGCAAATCATTAATGACATAGAAAAACTTGAAGTTTTCCCAGAAG
TTGGTTTTGATGCCGATGAAAAATATGGTTCAGAAATCAGCAATTATCACAGTACTAGAGGTTACACCTTAAGTAAAGAT
TATATTGTCCTATACCATATCGAAGAGGAAGAGAATAGCGTTGTCATTGATTACTTGCTTCCTACTCGAAGCGACTATAT
GAAATTGTTTAAATAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10906.50 Da        Isoelectric Point: 4.7271

>AT64546 WP_000259017.1 NZ_CP016391:c279537-279250 [Streptococcus agalactiae]
MVTVEKNRAVTFQANKELVSEAMTVLNKKNLTLSSALRLFLQNVVVTNEVDLLTEEELEKEKLFKQFQAEISKNIEDVRQ
GKFYTSEEVRAELGL

Download         Length: 288 bp

>AT64546 NZ_CP016391:c279537-279250 [Streptococcus agalactiae]
ATGGTTACAGTAGAAAAAAATAGAGCTGTCACATTCCAAGCTAACAAAGAATTGGTAAGCGAAGCAATGACAGTATTAAA
CAAAAAAAATTTAACCTTATCATCTGCTTTAAGATTATTCCTACAAAATGTCGTTGTCACAAACGAGGTTGACTTATTGA
CGGAAGAGGAGTTAGAGAAAGAAAAACTTTTCAAGCAATTTCAAGCCGAAATCAGCAAAAATATTGAGGATGTTCGTCAA
GGGAAGTTTTATACCTCTGAAGAAGTGAGGGCTGAACTTGGACTATAA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A076Z4V6

References