Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /GNAT-DUF1778 |
| Location | 8818..9584 | Replicon | chromosome |
| Accession | NZ_CP016384 | ||
| Organism | Vibrio mimicus strain SCCF01 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | vm_RS15140 | Protein ID | WP_070382631.1 |
| Coordinates | 8818..9315 (-) | Length | 166 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A0Q0PQR2 |
| Locus tag | vm_RS15145 | Protein ID | WP_000246255.1 |
| Coordinates | 9312..9584 (-) | Length | 91 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| vm_RS15105 | 4115..4468 | + | 354 | WP_070382626.1 | hypothetical protein | - |
| vm_RS15110 | 4621..5118 | + | 498 | WP_070382627.1 | GNAT family N-acetyltransferase | - |
| vm_RS15115 | 5257..5763 | + | 507 | WP_070382628.1 | GNAT family N-acetyltransferase | - |
| vm_RS15120 | 6062..6244 | + | 183 | WP_070382629.1 | DUF645 family protein | - |
| vm_RS21680 | 6603..6801 | + | 199 | Protein_11 | DUF645 family protein | - |
| vm_RS15125 | 6988..7473 | + | 486 | WP_196770050.1 | GNAT family N-acetyltransferase | - |
| vm_RS15130 | 7618..8100 | + | 483 | WP_070382630.1 | GNAT family N-acetyltransferase | - |
| vm_RS15135 | 8241..8675 | + | 435 | WP_032470918.1 | GNAT family N-acetyltransferase | - |
| vm_RS15140 | 8818..9315 | - | 498 | WP_070382631.1 | GNAT family N-acetyltransferase | Toxin |
| vm_RS15145 | 9312..9584 | - | 273 | WP_000246255.1 | DUF1778 domain-containing protein | Antitoxin |
| vm_RS15150 | 9976..10155 | + | 180 | WP_032469487.1 | DUF645 family protein | - |
| vm_RS15155 | 10366..10686 | + | 321 | WP_029797024.1 | DUF2834 domain-containing protein | - |
| vm_RS21145 | 10623..10805 | + | 183 | Protein_19 | DUF3265 domain-containing protein | - |
| vm_RS15160 | 10851..11165 | + | 315 | WP_155761235.1 | hypothetical protein | - |
| vm_RS15165 | 11344..11733 | + | 390 | WP_000678658.1 | GFA family protein | - |
| vm_RS21155 | 12253..12387 | + | 135 | WP_081337939.1 | DUF3265 domain-containing protein | - |
| vm_RS15170 | 12407..12655 | + | 249 | WP_070382633.1 | hypothetical protein | - |
| vm_RS15175 | 12669..12914 | + | 246 | WP_070382634.1 | hypothetical protein | - |
| vm_RS15180 | 13083..13634 | + | 552 | WP_005526531.1 | hypothetical protein | - |
| vm_RS15185 | 13799..14203 | + | 405 | WP_070382635.1 | MAPEG family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integron | - | cqsA / ugd / hlyA / vgrG-3 / vasL / icmF/vasK / vasJ / vasI / vasH / clpB/vasG / vasF / vasE / vasD / vasC / vasB / vasA / VCA0109 / vipB/mglB / vipB/mglB / vipA/mglA / vgrG-2 / hcp-2 / lfgG / hlyA | 41..1270905 | 1270864 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 166 a.a. Molecular weight: 18597.27 Da Isoelectric Point: 8.0186
>T64540 WP_070382631.1 NZ_CP016384:c9315-8818 [Vibrio mimicus]
MMNTVLLDKDKHDRNRFNCGIEALNNYLKVMASQQAKKDNTRTFVLEDDNNSAYIIGFYTLTMTPIDLKALPDKLQKKHQ
SSTSGGLIARLAVDDRYKGKGFGEWLLIDALRKLLAASDSVAFPVVIVDAKDGAKHFYERYGFQAFQDAENKLFITIADI
RASLD
MMNTVLLDKDKHDRNRFNCGIEALNNYLKVMASQQAKKDNTRTFVLEDDNNSAYIIGFYTLTMTPIDLKALPDKLQKKHQ
SSTSGGLIARLAVDDRYKGKGFGEWLLIDALRKLLAASDSVAFPVVIVDAKDGAKHFYERYGFQAFQDAENKLFITIADI
RASLD
Download Length: 498 bp
>T64540 NZ_CP016384:c9315-8818 [Vibrio mimicus]
ATGATGAATACGGTACTTCTCGATAAAGATAAGCACGATAGGAACCGTTTCAATTGTGGCATCGAAGCCCTCAACAATTA
CTTAAAAGTAATGGCGAGTCAGCAAGCCAAAAAAGACAACACCAGAACCTTCGTTTTGGAAGATGACAATAACAGTGCTT
ATATCATCGGCTTTTACACTCTGACTATGACACCCATTGATTTGAAAGCTTTGCCCGACAAGTTACAAAAGAAACACCAA
TCTTCAACCTCTGGAGGGCTCATTGCTCGTTTAGCTGTCGACGATAGATACAAAGGAAAAGGTTTTGGTGAGTGGCTACT
CATTGACGCTCTCAGAAAGCTACTCGCAGCCAGTGACAGCGTAGCGTTCCCTGTTGTCATCGTTGATGCCAAAGATGGTG
CAAAACATTTCTATGAGCGCTATGGGTTTCAAGCGTTTCAAGATGCTGAAAACAAACTCTTCATCACTATTGCTGATATC
AGAGCAAGCTTAGACTAG
ATGATGAATACGGTACTTCTCGATAAAGATAAGCACGATAGGAACCGTTTCAATTGTGGCATCGAAGCCCTCAACAATTA
CTTAAAAGTAATGGCGAGTCAGCAAGCCAAAAAAGACAACACCAGAACCTTCGTTTTGGAAGATGACAATAACAGTGCTT
ATATCATCGGCTTTTACACTCTGACTATGACACCCATTGATTTGAAAGCTTTGCCCGACAAGTTACAAAAGAAACACCAA
TCTTCAACCTCTGGAGGGCTCATTGCTCGTTTAGCTGTCGACGATAGATACAAAGGAAAAGGTTTTGGTGAGTGGCTACT
CATTGACGCTCTCAGAAAGCTACTCGCAGCCAGTGACAGCGTAGCGTTCCCTGTTGTCATCGTTGATGCCAAAGATGGTG
CAAAACATTTCTATGAGCGCTATGGGTTTCAAGCGTTTCAAGATGCTGAAAACAAACTCTTCATCACTATTGCTGATATC
AGAGCAAGCTTAGACTAG
Antitoxin
Download Length: 91 a.a. Molecular weight: 9713.24 Da Isoelectric Point: 6.2988
>AT64540 WP_000246255.1 NZ_CP016384:c9584-9312 [Vibrio mimicus]
MATTLPRITARVDVDTQDLLTKAAALAGMSSINSFVLNAAIEKAKQVIEREQALKLSQADAVLLMEALDNPAVVNAKLKL
ASERYESKTQ
MATTLPRITARVDVDTQDLLTKAAALAGMSSINSFVLNAAIEKAKQVIEREQALKLSQADAVLLMEALDNPAVVNAKLKL
ASERYESKTQ
Download Length: 273 bp
>AT64540 NZ_CP016384:c9584-9312 [Vibrio mimicus]
ATGGCAACGACTTTGCCTCGCATCACCGCTAGAGTTGATGTCGATACTCAAGATTTACTCACTAAGGCTGCCGCTCTTGC
TGGTATGTCTAGTATTAACTCATTTGTTTTGAATGCGGCAATCGAAAAAGCAAAACAAGTCATTGAACGTGAGCAAGCTC
TAAAGCTTAGCCAAGCTGATGCCGTATTGCTGATGGAAGCTCTTGATAATCCAGCGGTAGTAAATGCAAAGCTAAAATTG
GCATCCGAACGTTATGAGAGCAAAACTCAATGA
ATGGCAACGACTTTGCCTCGCATCACCGCTAGAGTTGATGTCGATACTCAAGATTTACTCACTAAGGCTGCCGCTCTTGC
TGGTATGTCTAGTATTAACTCATTTGTTTTGAATGCGGCAATCGAAAAAGCAAAACAAGTCATTGAACGTGAGCAAGCTC
TAAAGCTTAGCCAAGCTGATGCCGTATTGCTGATGGAAGCTCTTGATAATCCAGCGGTAGTAAATGCAAAGCTAAAATTG
GCATCCGAACGTTATGAGAGCAAAACTCAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|