Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 2699087..2700774 Replicon chromosome
Accession NZ_CP016383
Organism Vibrio mimicus strain SCCF01

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag vm_RS12625 Protein ID WP_029847931.1
Coordinates 2699087..2700310 (-) Length 408 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag vm_RS12630 Protein ID WP_070382296.1
Coordinates 2700307..2700774 (-) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
vm_RS12610 2695324..2697201 + 1878 WP_000372613.1 RNA polymerase sigma factor RpoD -
vm_RS12620 2697584..2698825 + 1242 WP_070382295.1 tyrosine-type recombinase/integrase -
vm_RS12625 2699087..2700310 - 1224 WP_029847931.1 RelA/SpoT domain-containing protein Toxin
vm_RS12630 2700307..2700774 - 468 WP_070382296.1 DUF4065 domain-containing protein Antitoxin
vm_RS12635 2701028..2701699 - 672 WP_070382297.1 hypothetical protein -
vm_RS12640 2701844..2702881 + 1038 WP_070382298.1 helix-turn-helix domain-containing protein -
vm_RS12645 2703048..2703692 + 645 WP_070382299.1 inovirus Gp2 family protein -
vm_RS12650 2703734..2704180 - 447 WP_070382300.1 hypothetical protein -
vm_RS12655 2704291..2705280 - 990 WP_070382301.1 50S ribosome-binding GTPase -
vm_RS12660 2705358..2705579 + 222 WP_047109997.1 AlpA family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2699087..2714449 15362


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(86-226)

Antitoxin

Antitoxin SocA-like, Panacea domain

(32-122)


Sequences

Toxin        


Download         Length: 408 a.a.        Molecular weight: 45962.70 Da        Isoelectric Point: 5.1409

>T64539 WP_029847931.1 NZ_CP016383:c2700310-2699087 [Vibrio mimicus]
VSDKENSVVSFYIDDTPTAEQASKTFQDDYELDFQDFIERTVNESAAEDFSYSNNGVKKAGRRLRKREGDLKSATATIQQ
FRAAHEKPLNTIAYLVGRCCRELGIDVKPVTRLKRLETIVDKLQRKSLDGETANATCVTNMNDIGGCRVIFPDLISLEKV
QSQLQLTVEKVGRVRIKDIDDYITSPKPNDCGYRSLHVIYRYDHASGKSFNIEAQLRTRLQHLWATTVEIVDILEGTKIK
THSHSSNEDKSSLQIQWEELLSIMSQYIADAEGAIELSDVDKANFSKRLIVLDREINALNRLSSFKILSEKVNSCCDNSI
EHVLLVINETSRELIFSEEFENYSQAISVYNAAEKVTRSYSRSTSRLNTLLISTKNMGQLSEAYPNYLGDCASFITLLED
AMLSGES

Download         Length: 1224 bp

>T64539 NZ_CP016383:c2700310-2699087 [Vibrio mimicus]
GTGAGTGACAAAGAAAATAGTGTTGTCAGTTTTTACATTGACGACACTCCTACCGCAGAACAAGCTTCAAAAACCTTCCA
AGACGACTACGAGCTGGACTTTCAAGATTTTATAGAAAGAACGGTAAATGAAAGTGCTGCTGAAGACTTCTCGTACTCAA
ACAATGGAGTAAAGAAAGCTGGAAGACGACTGCGTAAGAGAGAGGGCGACCTCAAGTCAGCTACTGCTACAATCCAACAG
TTTCGAGCCGCACACGAAAAGCCATTAAACACTATCGCATATCTTGTTGGTCGCTGTTGCCGGGAACTGGGTATAGATGT
AAAACCAGTTACACGGTTAAAGCGTTTAGAAACAATCGTAGATAAGTTGCAGCGTAAATCTCTTGATGGTGAAACGGCAA
ATGCTACTTGTGTGACCAATATGAATGATATTGGCGGTTGCAGGGTGATTTTCCCGGATTTAATTTCCTTGGAGAAGGTG
CAGTCTCAACTGCAACTTACCGTTGAAAAGGTAGGCCGAGTTAGAATCAAAGATATTGATGATTATATTACTAGCCCTAA
GCCTAATGATTGTGGTTACCGAAGCTTGCATGTGATTTATCGCTATGACCATGCTAGCGGTAAAAGTTTTAACATTGAGG
CTCAGCTACGTACTCGACTTCAACATCTTTGGGCAACTACTGTGGAAATTGTCGACATCCTGGAAGGCACCAAGATTAAG
ACTCACTCTCACAGTTCAAATGAAGATAAGAGCAGTTTACAGATTCAATGGGAAGAATTGCTTTCGATCATGAGCCAGTA
CATTGCTGATGCTGAAGGGGCTATAGAGCTAAGTGATGTCGATAAAGCCAATTTTTCAAAGCGCTTGATCGTCTTGGACC
GCGAAATCAATGCGCTGAATCGATTGAGTAGTTTTAAAATTTTATCTGAAAAGGTGAATTCTTGCTGTGATAACTCTATT
GAGCACGTATTGCTAGTTATTAACGAAACCTCACGAGAATTGATCTTTAGTGAAGAGTTTGAAAATTACAGTCAGGCAAT
TTCAGTTTACAACGCGGCTGAGAAAGTCACTCGTAGCTACTCAAGATCAACCTCGAGACTCAATACCCTTCTCATCTCCA
CAAAAAATATGGGGCAACTTTCGGAAGCCTACCCTAACTATCTAGGCGATTGTGCCTCATTCATCACTCTGCTTGAAGAC
GCAATGCTTTCTGGTGAAAGCTAA

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17536.02 Da        Isoelectric Point: 8.2954

>AT64539 WP_070382296.1 NZ_CP016383:c2700774-2700307 [Vibrio mimicus]
MKAYHTYSAVDVAWSLLKHAKEQGKCFSNLQLQKLTYVCHGLSLAHFQRPLVVDDVFAWKFGPVVPSVYFRFKSYGSSVI
TEQCDVALDQESESIVKDVVSKLGHLTGPQLVDLTHREGSPWRQVWDGTHQKVIPDHLIQAHYTQIKQSGRTASL

Download         Length: 468 bp

>AT64539 NZ_CP016383:c2700774-2700307 [Vibrio mimicus]
ATGAAAGCATATCACACATACAGTGCTGTAGACGTTGCATGGAGCTTGCTCAAGCATGCGAAAGAGCAAGGTAAATGCTT
CTCCAATTTGCAGCTACAAAAACTTACCTATGTTTGTCATGGTTTATCATTGGCGCATTTCCAGCGTCCTCTCGTCGTAG
ATGATGTATTTGCTTGGAAGTTTGGTCCAGTGGTGCCATCTGTTTACTTCCGCTTTAAATCTTATGGTAGTAGTGTGATC
ACTGAGCAATGTGATGTTGCACTAGACCAAGAAAGTGAGTCTATTGTCAAAGATGTTGTATCTAAACTTGGCCATTTGAC
GGGGCCTCAACTTGTAGATTTAACTCACCGAGAGGGAAGTCCATGGCGTCAGGTATGGGACGGCACACACCAAAAAGTGA
TTCCGGATCATTTGATTCAAGCCCATTACACTCAAATCAAACAATCCGGACGAACAGCTAGCCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References