Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-CcdA
Location 1137079..1137727 Replicon chromosome
Accession NZ_CP016353
Organism Prauserella marina strain DSM 45268

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BAY61_RS05170 Protein ID WP_091799111.1
Coordinates 1137299..1137727 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BAY61_RS05165 Protein ID WP_091800660.1
Coordinates 1137079..1137306 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BAY61_RS05140 1132128..1132547 + 420 WP_091799101.1 hypothetical protein -
BAY61_RS05145 1132592..1133533 - 942 WP_091800658.1 sigma-70 family RNA polymerase sigma factor -
BAY61_RS05150 1133544..1134743 - 1200 WP_091799104.1 FAD-dependent oxidoreductase -
BAY61_RS05155 1134833..1135720 - 888 WP_091799106.1 RNA polymerase sigma-70 factor -
BAY61_RS05160 1135727..1136926 - 1200 WP_091799109.1 FAD-dependent oxidoreductase -
BAY61_RS05165 1137079..1137306 + 228 WP_091800660.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
BAY61_RS05170 1137299..1137727 + 429 WP_091799111.1 type II toxin-antitoxin system VapC family toxin Toxin
BAY61_RS05175 1137735..1139459 - 1725 WP_091799113.1 asparagine synthase C-terminal domain-containing protein -
BAY61_RS05180 1139469..1139975 - 507 WP_091800662.1 hypothetical protein -
BAY61_RS05185 1139993..1140790 - 798 WP_091799116.1 hypothetical protein -
BAY61_RS05190 1140787..1141854 - 1068 WP_091799119.1 hypothetical protein -
BAY61_RS05195 1141914..1142645 + 732 WP_091799122.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Pae0151-like, PIN domain

(10-125)

Antitoxin

Post-segregation antitoxin CcdA

(3-45)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 14907.18 Da        Isoelectric Point: 6.8814

>T64494 WP_091799111.1 NZ_CP016353:1137299-1137727 [Prauserella marina]
MTEPPAELVVVDASVLVDLLAGTDYAAPAKERLVNTVLHAPAHMDAEVFSAIGRLQRAGKLTTADVDAALSALATIPVKR
HPVAELTVGAWTRRADLRLTDALYIELAARLRVPVLTTDHRLARASSLAEGIALGSPRGASG

Download         Length: 429 bp

>T64494 NZ_CP016353:1137299-1137727 [Prauserella marina]
ATGACTGAGCCGCCCGCCGAGCTCGTGGTAGTCGACGCGTCGGTTCTCGTCGATCTGCTTGCCGGTACCGACTATGCGGC
ACCGGCGAAGGAGCGGCTGGTCAACACCGTCCTGCACGCGCCGGCGCACATGGACGCCGAGGTGTTTTCCGCTATCGGTC
GACTTCAGCGTGCTGGAAAGCTGACCACGGCCGATGTCGACGCGGCACTGTCGGCGTTGGCCACGATCCCCGTGAAGCGC
CACCCCGTTGCCGAGTTGACGGTCGGTGCGTGGACACGCAGGGCGGATCTCCGCTTGACTGACGCGCTGTACATCGAACT
CGCCGCCCGGCTACGGGTGCCGGTCCTCACCACCGATCACCGCCTCGCGCGCGCGAGTTCGCTTGCCGAAGGCATCGCAC
TCGGATCACCGCGTGGGGCGTCAGGCTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8030.92 Da        Isoelectric Point: 4.2813

>AT64494 WP_091800660.1 NZ_CP016353:1137079-1137306 [Prauserella marina]
MARLNVYLSDELAERAKVAGLNISALAQAAIADELRRRDTNSWLASLPEPRGTVSHGVALEALDDAREELAGADD

Download         Length: 228 bp

>AT64494 NZ_CP016353:1137079-1137306 [Prauserella marina]
ATGGCACGGCTGAACGTGTACCTGTCTGACGAGCTGGCCGAGCGGGCCAAGGTCGCCGGCTTGAACATTTCCGCTCTCGC
GCAGGCCGCGATCGCCGACGAGTTGCGCCGCCGGGATACGAACTCGTGGTTGGCCTCGCTGCCCGAGCCGCGCGGCACGG
TCTCCCATGGCGTCGCCCTTGAGGCGCTGGATGATGCTCGCGAGGAGTTGGCGGGCGCGGATGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References