Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 744698..746373 Replicon chromosome
Accession NZ_CP016349
Organism Vibrio natriegens strain CCUG 16373

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag BA893_RS03365 Protein ID WP_065299198.1
Coordinates 745162..746373 (+) Length 404 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag BA893_RS03360 Protein ID WP_065299197.1
Coordinates 744698..745165 (+) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BA893_RS03340 740022..741119 + 1098 WP_065299193.1 site-specific integrase -
BA893_RS03345 741277..741864 + 588 WP_065299194.1 recombinase family protein -
BA893_RS03350 742108..743745 + 1638 WP_065299195.1 RNA-directed DNA polymerase -
BA893_RS03355 743772..744479 + 708 WP_155759966.1 hypothetical protein -
BA893_RS03360 744698..745165 + 468 WP_065299197.1 DUF4065 domain-containing protein Antitoxin
BA893_RS03365 745162..746373 + 1212 WP_065299198.1 hypothetical protein Toxin
BA893_RS03370 746453..747700 - 1248 WP_065299199.1 tyrosine-type recombinase/integrase -
BA893_RS03380 748301..748786 - 486 WP_014230976.1 SsrA-binding protein SmpB -
BA893_RS03385 748905..749348 + 444 WP_014230977.1 ubiquinone-binding protein -
BA893_RS03390 749338..749691 + 354 WP_065299200.1 RnfH family protein -
BA893_RS03395 749754..750113 - 360 WP_014230979.1 outer membrane protein assembly factor BamE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 737981..747700 9719


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(111-228)

Antitoxin

Antitoxin SocA-like, Panacea domain

(32-123)


Sequences

Toxin        


Download         Length: 404 a.a.        Molecular weight: 45432.28 Da        Isoelectric Point: 5.1420

>T64491 WP_065299198.1 NZ_CP016349:745162-746373 [Vibrio natriegens]
VSDKQKSVVSFHIDDTPTAEQASIAFQDDYELDFQDFLERTVDESAAEDFSYSNNGVKKAGRRLRKKEGDLKSATATIQQ
FRAAHEKPLNTIAYLVGRCCRELGIDVKPVTRLKRLETIIDKLQRKSLDGETTNATCVTNMNDIGGCRAIFPDLMSLEKV
KAQLQVTVEKARRVKIKDIDDYIANPKPNDCGYRSLHVIYRYDHASGKSFNIEAQLRTRLQHLWATTVEIVDILEGTKIK
THSHSPDEDKGSLQIQWEELLSIMSQYIADAEGAIELSECDRVRFSNRLVELNSEINALSRLRSFKILSEKVEGCCDGST
EHVLVVIDETSLQMIFSEEFENYSQAISVYNAAEKMTRSYARVNTLLISTKNMGQLSEAYPNYLGDCASFITLFEDAMTS
GVS

Download         Length: 1212 bp

>T64491 NZ_CP016349:745162-746373 [Vibrio natriegens]
GTGAGTGATAAACAAAAAAGTGTCGTCAGTTTTCACATTGACGACACTCCTACCGCCGAACAGGCATCCATAGCTTTTCA
AGATGACTACGAACTAGATTTTCAAGATTTTCTTGAAAGAACGGTTGATGAAAGCGCTGCAGAAGACTTCTCATACTCCA
ACAATGGGGTGAAGAAAGCAGGACGACGGCTACGCAAGAAAGAGGGTGACCTTAAATCAGCCACTGCGACAATCCAACAG
TTTCGTGCAGCTCATGAAAAACCACTGAACACAATCGCTTATCTTGTTGGCCGATGTTGTCGAGAGTTAGGTATAGATGT
TAAACCAGTGACACGACTAAAACGCTTAGAAACTATAATAGACAAGCTACAGCGTAAATCTCTTGATGGAGAAACTACGA
ACGCGACTTGTGTGACCAATATGAATGATATTGGTGGGTGTAGAGCGATTTTTCCTGATCTAATGTCGTTGGAGAAAGTA
AAAGCGCAACTACAAGTAACAGTTGAAAAAGCACGTCGAGTTAAAATTAAGGACATTGATGATTACATCGCCAACCCTAA
ACCTAATGACTGTGGTTACCGAAGTTTGCATGTTATCTATCGTTATGATCATGCTAGCGGCAAAAGCTTTAATATAGAAG
CTCAGCTGCGCACCCGGCTCCAACACCTCTGGGCAACTACAGTAGAAATTGTCGATATCTTAGAGGGTACTAAGATTAAG
ACTCATTCTCATAGTCCAGATGAAGATAAAGGTAGTTTGCAGATTCAATGGGAAGAGCTACTCTCCATCATGAGTCAGTA
TATTGCTGACGCTGAAGGTGCTATAGAGTTAAGTGAATGCGATAGAGTTCGATTTTCAAATCGACTGGTTGAATTGAATA
GCGAAATTAATGCATTGAGTCGGTTGAGAAGTTTTAAAATTCTATCGGAAAAAGTTGAAGGCTGTTGCGATGGTTCAACA
GAACATGTTCTAGTAGTGATTGACGAAACTTCGCTACAAATGATCTTTAGTGAAGAGTTTGAGAATTATAGCCAAGCTAT
TTCGGTTTATAATGCTGCCGAGAAGATGACGCGTAGCTATGCGAGAGTAAATACTCTTCTCATATCTACAAAAAATATGG
GGCAGCTGTCAGAAGCATACCCAAACTATCTAGGTGATTGCGCTTCATTTATCACGCTGTTTGAAGACGCTATGACATCT
GGAGTAAGTTAA

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17531.94 Da        Isoelectric Point: 7.2466

>AT64491 WP_065299197.1 NZ_CP016349:744698-745165 [Vibrio natriegens]
MKAYHTYSAVDVAWSLLKHAKEQGKCFSNLQLQKLTYVCHGLSLAHFQRPLVVDDVFAWKFGPVVPSVYFRFKSYGSSVI
TEQCDVVLDHESESIVKDVVSQLGDLTGPQLVDLTHREGSPWHQVWDGTHQKVIPDHLIQAHYTQIKQSGRTASL

Download         Length: 468 bp

>AT64491 NZ_CP016349:744698-745165 [Vibrio natriegens]
ATGAAAGCATATCACACATACAGTGCTGTAGACGTTGCATGGAGCTTGCTTAAGCATGCGAAAGAGCAAGGTAAATGCTT
CTCTAATTTGCAGCTGCAAAAACTTACCTATGTTTGTCATGGTTTATCATTGGCGCACTTCCAGCGTCCTCTAGTCGTAG
ATGACGTATTTGCTTGGAAGTTTGGCCCAGTTGTGCCATCTGTCTACTTTCGTTTTAAATCTTACGGTAGTAGTGTGATC
ACTGAACAATGTGATGTGGTGTTAGATCATGAAAGTGAATCTATTGTAAAAGATGTAGTATCACAGTTGGGTGATTTAAC
GGGTCCTCAACTAGTAGATTTAACTCATCGCGAGGGGAGCCCATGGCATCAAGTATGGGATGGCACACATCAAAAAGTGA
TTCCAGACCATTTGATCCAAGCCCATTACACCCAGATCAAACAATCAGGACGTACAGCTAGCCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References