Detailed information of TA system TA064458

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1421231..1422135
• Replicon: chromosome
• Accession: NZ_CP016337
• Organism: Kosakonia sacchari strain BO-1

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: BBB57_RS06860
• Protein ID: WP_065368890.1
• Coordinates: 1421671..1422135 (+)
• Length: 155 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: BBB57_RS06855
• Protein ID: WP_065368889.1
• Coordinates: 1421231..1421674 (+)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BBB57_RS06835	1416271..1418037	+	1767	WP_065368886.1	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	-
BBB57_RS06840	1418038..1419759	+	1722	WP_065368887.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-
BBB57_RS06845	1419866..1420567	+	702	WP_065368888.1	leucyl/phenylalanyl-tRNA--protein transferase	-
BBB57_RS06850	1420856..1421074	+	219	WP_001040187.1	translation initiation factor IF-1	-
BBB57_RS06855	1421231..1421674	+	444	WP_065368889.1	DUF2384 domain-containing protein	Antitoxin
BBB57_RS06860	1421671..1422135	+	465	WP_065368890.1	RES domain-containing protein	Toxin
BBB57_RS06865	1422179..1422698	+	520	Protein_1368	GGDEF domain-containing protein	-
BBB57_RS06870	1422766..1425057	-	2292	WP_017456165.1	ATP-dependent Clp protease ATP-binding subunit ClpA	-
BBB57_RS06875	1425088..1425408	-	321	WP_017456164.1	ATP-dependent Clp protease adapter ClpS	-
BBB57_RS06880	1425737..1425958	+	222	WP_007374119.1	cold shock-like protein CspD	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-147)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (29-90)

Sequences

Toxin

Protein

• Length: 155 a.a.
• Molecular weight: 17144.61 Da
• Isoelectric Point: 6.2127

>T64458 WP_065368890.1 NZ_CP016337:1421671-1422135 [Kosakonia sacchari]
VIFYRLVTRRYASETWTGSGANLYGGRWNHKGHPAVYVASSVSLAALEMLVHVHSDTVLNQYGLFSIEIPDKDIEHLDKQ
WLPPDWQENPAPLSTMDLGTAWLEANSAVALVLPSCVIPLENNAILNPLHPAFNKLLKTVKELPFSFDPRLANA

Nucleotide

• Length: 465 bp

>T64458 NZ_CP016337:1421671-1422135 [Kosakonia sacchari]
GTGATCTTCTATCGACTGGTAACGCGCCGCTACGCCAGCGAAACCTGGACAGGCAGCGGTGCAAATCTTTATGGCGGGCG
CTGGAATCACAAGGGTCATCCGGCGGTTTACGTCGCTTCGTCCGTTTCACTTGCCGCACTCGAAATGCTGGTACATGTGC
ACAGCGACACGGTTCTGAACCAGTATGGGCTGTTCAGTATTGAGATCCCTGACAAGGATATTGAACATCTGGATAAGCAG
TGGCTACCGCCAGACTGGCAGGAAAACCCGGCACCGCTTTCGACCATGGATTTAGGTACCGCCTGGCTGGAAGCCAACAG
CGCCGTCGCACTGGTGCTGCCGTCATGCGTTATTCCGCTTGAGAATAATGCGATTCTTAACCCGCTTCATCCTGCTTTTA
ATAAGCTGCTAAAAACCGTAAAAGAGCTTCCTTTCTCTTTCGATCCACGCCTGGCAAACGCGTAA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16449.90 Da
• Isoelectric Point: 8.8231

>AT64458 WP_065368889.1 NZ_CP016337:1421231-1421674 [Kosakonia sacchari]
MRTWSPDQKPVENALWRFAGFPANRGLKLVQMLNEGLPVSILDNIHEWTEMSRSDILRVTGINERNVARRKSAGRTLTPE
ESERIARLVRVVDAAVQFFGSKKMAWDWLETPVRGLGNVAPISLIATESGALEVTDLLGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT64458 NZ_CP016337:1421231-1421674 [Kosakonia sacchari]
ATGAGAACCTGGAGTCCGGATCAAAAACCGGTCGAAAATGCGCTCTGGCGCTTTGCCGGTTTCCCTGCCAACCGAGGGCT
AAAACTCGTTCAGATGTTAAACGAGGGCTTGCCTGTCAGCATTCTCGACAATATTCATGAATGGACAGAAATGTCCCGCT
CCGACATTCTGCGCGTCACCGGTATTAATGAACGCAATGTCGCGCGTCGCAAAAGCGCCGGCCGCACACTCACGCCGGAA
GAAAGTGAGCGCATTGCGCGTTTAGTCAGAGTTGTTGATGCCGCGGTACAGTTTTTCGGTAGCAAAAAGATGGCGTGGGA
CTGGCTGGAAACCCCCGTTCGCGGCCTTGGCAACGTAGCGCCGATTTCGCTGATTGCCACCGAAAGTGGCGCGCTGGAAG
TAACCGACCTGCTCGGCAGGCTGGAGCACGGAGTATTTGCGTGA