Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafN(antitoxin)
Location 1688311..1688876 Replicon chromosome
Accession NZ_CP016321
Organism Vibrio vulnificus strain FORC_037

Toxin (Protein)


Gene name relE Uniprot ID A0A7X8U0A9
Locus tag FORC37_RS08210 Protein ID WP_029865673.1
Coordinates 1688311..1688598 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID U3BLE1
Locus tag FORC37_RS08215 Protein ID WP_000086647.1
Coordinates 1688595..1688876 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC37_RS08155 1683854..1684396 - 543 WP_088427781.1 DinB family protein -
FORC37_RS08160 1684424..1684516 - 93 WP_004418565.1 DUF3265 domain-containing protein -
FORC37_RS08165 1684537..1685130 - 594 WP_088427782.1 hypothetical protein -
FORC37_RS08170 1685142..1685270 - 129 WP_088428244.1 DUF3265 domain-containing protein -
FORC37_RS08175 1685601..1685729 - 129 WP_088428245.1 DUF3265 domain-containing protein -
FORC37_RS08180 1686207..1686734 - 528 WP_039470306.1 hypothetical protein -
FORC37_RS08185 1686743..1686874 - 132 WP_088428246.1 DUF3265 domain-containing protein -
FORC37_RS08195 1687222..1687350 - 129 WP_079854177.1 DUF3265 domain-containing protein -
FORC37_RS24245 1687704..1687823 - 120 Protein_1543 DUF3265 domain-containing protein -
FORC37_RS08210 1688311..1688598 - 288 WP_029865673.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FORC37_RS08215 1688595..1688876 - 282 WP_000086647.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FORC37_RS08220 1688833..1689078 - 246 WP_088427785.1 DUF3265 domain-containing protein -
FORC37_RS08225 1689423..1689551 - 129 WP_088427786.1 DUF3265 domain-containing protein -
FORC37_RS08235 1689901..1690029 - 129 WP_088428247.1 DUF3265 domain-containing protein -
FORC37_RS08245 1690885..1690992 - 108 WP_080722308.1 DUF3265 domain-containing protein -
FORC37_RS08250 1691323..1691451 - 129 WP_088428250.1 DUF3265 domain-containing protein -
FORC37_RS08260 1691811..1691903 - 93 WP_198300226.1 DUF3265 domain-containing protein -
FORC37_RS08265 1691918..1692334 - 417 WP_046876173.1 hypothetical protein -
FORC37_RS08270 1692304..1692504 - 201 WP_088428251.1 DUF3265 domain-containing protein -
FORC37_RS08275 1692570..1693538 + 969 WP_088427780.1 IS30-like element ISVvu6 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1624817..1757381 132564
- flank IS/Tn - - 1692570..1693538 968
- inside Integron - - 1630666..1757381 126715


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-74)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10993.65 Da        Isoelectric Point: 5.1098

>T64424 WP_029865673.1 NZ_CP016321:c1688598-1688311 [Vibrio vulnificus]
MKVVWSPLALQKLGDAAEFISLDNPSAAEKWVNEVFDKTELLGSMPEMGRFVPEMPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQILSEDDV

Download         Length: 288 bp

>T64424 NZ_CP016321:c1688598-1688311 [Vibrio vulnificus]
ATGAAAGTAGTTTGGTCTCCATTAGCGCTTCAGAAGCTAGGCGATGCAGCGGAGTTTATTTCTTTGGATAATCCATCTGC
GGCAGAAAAGTGGGTAAATGAAGTTTTTGATAAAACCGAACTACTTGGAAGCATGCCTGAAATGGGGCGCTTTGTTCCTG
AAATGCCCCATACGAACTATCGTGAAATCATCTTTGGTCACTATCGGATTATCTACAGCTTAAGTCACGAAATCCGCGTG
CTAACAGTTCGTAATTGTCGCCAAATACTGTCTGAAGATGACGTGTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10398.91 Da        Isoelectric Point: 5.8650

>AT64424 WP_000086647.1 NZ_CP016321:c1688876-1688595 [Vibrio vulnificus]
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
DDARAQVLGRIKK

Download         Length: 282 bp

>AT64424 NZ_CP016321:c1688876-1688595 [Vibrio vulnificus]
ATGAGTCGTATTCATTTCGATCAAGATATTCAGCCGTTATCTGAATTTCGTGCAGGTGTTGCTTCTTACATCAAACAAAT
CAATGAGACTCGCCGTCCATTGGTCATTACACAGCGTGGTAAAGGTGTTGCTGTTGTTCTTGATGTTGCAGAGTATGAAG
CAATGCAAGAGAAAATCGAATTACTAGAAGAAATGCGCACAGCTGAAGCTCAATTAGCTTCAGGCCTTGGTGTTTCCAAT
GATGATGCTCGTGCTCAAGTACTGGGGCGCATTAAGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7X8U0A9

Antitoxin

Source ID Structure
AlphaFold DB A0A4P8G0X0

References