Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 116307..117109 Replicon plasmid unnamed1
Accession NZ_CP016287
Organism Rhizobium leguminosarum strain Vaf10

Toxin (Protein)


Gene name TacT3 Uniprot ID A0A1B1CHC7
Locus tag BA011_RS24975 Protein ID WP_065282742.1
Coordinates 116307..116834 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID A0A1B1CH27
Locus tag BA011_RS24980 Protein ID WP_020046930.1
Coordinates 116831..117109 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BA011_RS24965 112890..114014 - 1125 WP_065282740.1 metallophosphoesterase -
BA011_RS24970 114370..116010 - 1641 WP_065282741.1 acetolactate synthase large subunit -
BA011_RS24975 116307..116834 - 528 WP_065282742.1 GNAT family N-acetyltransferase Toxin
BA011_RS24980 116831..117109 - 279 WP_020046930.1 DUF1778 domain-containing protein Antitoxin
BA011_RS24985 117330..118208 - 879 WP_065282743.1 exopolysaccharide synthesis protein -
BA011_RS24990 118622..119344 - 723 WP_065282744.1 ribonuclease activity regulator RraA -
BA011_RS24995 119424..120200 - 777 WP_065282745.1 IclR family transcriptional regulator -
BA011_RS25000 120415..121935 + 1521 WP_065282746.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..1254530 1254530


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(12-87)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 18787.75 Da        Isoelectric Point: 9.5507

>T64369 WP_065282742.1 NZ_CP016287:c116834-116307 [Rhizobium leguminosarum]
VTLPVWHEEPIAKSHDRASFDCGDAAMNEFIRRFARQSHEQNAAKTFCAIDKAQPDRILGFYTVAPSAVTHEAVPPKLTR
GLARHEVAGFKLARLATDIKVAGKGLGGQLIAAAALRCLRLASEGGGILLIIDAKSERAAHWYASYGAEPLQGKPLTLVM
PLATFAADFKAKGLL

Download         Length: 528 bp

>T64369 NZ_CP016287:c116834-116307 [Rhizobium leguminosarum]
GTGACCCTCCCCGTCTGGCATGAAGAGCCGATCGCTAAGTCGCACGATCGGGCCTCATTCGATTGCGGTGATGCGGCAAT
GAACGAGTTCATTCGGCGCTTCGCTCGGCAGAGCCATGAGCAGAATGCGGCGAAGACCTTCTGCGCTATCGACAAAGCCC
AACCTGATCGCATCCTCGGATTCTACACAGTCGCGCCTTCGGCTGTTACGCATGAGGCCGTGCCTCCAAAGCTGACGAGA
GGCCTCGCACGCCATGAAGTCGCAGGCTTCAAGCTTGCGCGCTTGGCAACCGACATAAAGGTGGCGGGAAAGGGTTTAGG
CGGCCAGCTCATCGCTGCTGCAGCGCTCCGTTGCCTGCGGCTCGCCAGCGAGGGCGGCGGGATCCTGCTCATCATCGATG
CCAAGAGCGAACGCGCCGCCCATTGGTATGCCAGCTATGGCGCCGAACCGCTGCAAGGGAAACCGCTCACCCTCGTTATG
CCGCTTGCCACCTTCGCCGCCGACTTCAAGGCCAAGGGGCTCTTGTAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10189.87 Da        Isoelectric Point: 8.6184

>AT64369 WP_020046930.1 NZ_CP016287:c117109-116831 [Rhizobium leguminosarum]
MPRTADNKTERYQLRIPPKQKAMIARAAALSNKDMADFILDKIVPEAEAVIQAAEVETVSSRDFIRILDLLEHPPKPNAK
LRAAISALPDAL

Download         Length: 279 bp

>AT64369 NZ_CP016287:c117109-116831 [Rhizobium leguminosarum]
ATGCCGAGAACCGCGGACAACAAAACCGAACGCTACCAGCTGCGTATCCCGCCAAAGCAGAAGGCAATGATCGCGCGCGC
GGCTGCCCTCTCGAACAAGGATATGGCCGATTTCATTCTCGATAAGATAGTACCTGAAGCCGAAGCCGTCATCCAGGCTG
CTGAAGTTGAGACCGTGTCGAGCCGCGATTTCATCCGCATCCTCGACCTGCTTGAACACCCGCCCAAACCGAACGCGAAA
CTACGCGCTGCGATCTCTGCTCTACCGGATGCCCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B1CHC7

Antitoxin

Source ID Structure
AlphaFold DB A0A1B1CH27

References