Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) slvAT/RES(toxin)
Location 1817425..1818320 Replicon chromosome
Accession NZ_CP016278
Organism Diaphorobacter polyhydroxybutyrativorans strain SL-205

Toxin (Protein)


Gene name slvT Uniprot ID -
Locus tag BA022_RS08615 Protein ID WP_088887212.1
Coordinates 1817425..1817952 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID -
Locus tag BA022_RS08620 Protein ID WP_088887213.1
Coordinates 1817949..1818320 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BA022_RS08585 1812583..1813074 + 492 WP_088887206.1 hypothetical protein -
BA022_RS08590 1813173..1813484 + 312 WP_088887207.1 hypothetical protein -
BA022_RS08595 1813599..1814312 - 714 WP_187306034.1 autoinducer binding domain-containing protein -
BA022_RS08600 1814314..1815162 - 849 WP_088887209.1 class I SAM-dependent methyltransferase -
BA022_RS08605 1815164..1815844 - 681 WP_187306035.1 class I SAM-dependent methyltransferase -
BA022_RS08610 1815893..1816981 + 1089 WP_088887211.1 IS5 family transposase -
BA022_RS08615 1817425..1817952 - 528 WP_088887212.1 RES family NAD+ phosphorylase Toxin
BA022_RS08620 1817949..1818320 - 372 WP_088887213.1 DUF2384 domain-containing protein Antitoxin
BA022_RS08625 1818518..1819165 - 648 WP_088887214.1 RES family NAD+ phosphorylase -
BA022_RS08630 1819162..1819836 - 675 WP_088887215.1 hypothetical protein -
BA022_RS08635 1819926..1821638 - 1713 WP_187306036.1 phosphoadenosine phosphosulfate reductase family protein -
BA022_RS08640 1821782..1821997 - 216 WP_088887217.1 hypothetical protein -
BA022_RS08645 1822259..1822531 + 273 WP_088887218.1 helix-turn-helix domain-containing protein -
BA022_RS08650 1822590..1822784 - 195 WP_088887219.1 hypothetical protein -
BA022_RS08655 1822787..1823284 - 498 WP_088887220.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - pvdF 1774341..2009748 235407


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(15-168)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(71-120)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19138.67 Da        Isoelectric Point: 4.6228

>T64362 WP_088887212.1 NZ_CP016278:c1817952-1817425 [Diaphorobacter polyhydroxybutyrativorans]
MILAVTLGEGKDEACYRVISPAYAGVPLSGMGAARQGGRFNRPGQEALYLSLDETTALAEYKQDNPWLRPGTICTFFVRG
LRVADLSAGFDPANWPPLWADFSVDWRAEWFGKSVEPPTWYMADDVAAEGLDGILFPSQARPGGLNLVVYRSSSRPVDQL
RVYDPDGALGKIAPR

Download         Length: 528 bp

>T64362 NZ_CP016278:c1817952-1817425 [Diaphorobacter polyhydroxybutyrativorans]
ATGATCCTGGCCGTCACGCTCGGCGAGGGCAAGGACGAGGCCTGCTACCGCGTCATCTCGCCAGCCTACGCCGGCGTGCC
GCTGTCCGGCATGGGCGCTGCGCGCCAGGGCGGCCGCTTCAACCGACCGGGGCAGGAGGCGCTCTACCTGTCGCTGGACG
AAACCACCGCCCTGGCCGAGTACAAGCAGGACAACCCCTGGCTGCGGCCGGGCACGATCTGCACTTTCTTCGTTCGCGGC
TTGCGGGTCGCTGACCTCAGCGCCGGTTTCGACCCGGCGAACTGGCCGCCGCTGTGGGCCGATTTTTCAGTGGACTGGCG
GGCGGAGTGGTTCGGCAAGTCCGTCGAGCCGCCCACCTGGTACATGGCCGACGATGTCGCCGCCGAGGGGCTGGACGGCA
TCCTGTTCCCCTCGCAGGCCCGCCCCGGCGGCCTCAATCTGGTGGTCTATCGGAGTTCGTCCCGGCCTGTCGATCAATTG
CGCGTATACGACCCCGACGGCGCTCTGGGAAAGATCGCGCCTCGGTAA

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13709.54 Da        Isoelectric Point: 5.7362

>AT64362 WP_088887213.1 NZ_CP016278:c1818320-1817949 [Diaphorobacter polyhydroxybutyrativorans]
MSTVLQQPFAEQFREPDTPYLSPARIGDFFGFKVQELAERAHVHRNTPTARPQAPQLQKYLQDMVRVLAVATEMTGDEKR
AAFLLRNEPLRAFGYKTADALIQDGRADTLIAYLESLAGGAEG

Download         Length: 372 bp

>AT64362 NZ_CP016278:c1818320-1817949 [Diaphorobacter polyhydroxybutyrativorans]
ATGAGCACCGTGCTGCAACAACCCTTCGCCGAGCAGTTCCGCGAACCGGACACGCCCTACCTGTCGCCGGCCCGGATCGG
GGATTTCTTCGGCTTCAAGGTCCAGGAACTGGCCGAGCGTGCCCACGTCCATCGAAACACCCCGACCGCCAGGCCCCAGG
CCCCTCAGTTGCAAAAGTATCTGCAGGACATGGTGCGGGTGCTGGCCGTGGCGACCGAGATGACCGGCGATGAAAAGCGC
GCAGCATTCCTGCTGCGCAACGAGCCGCTGCGCGCCTTCGGCTACAAGACGGCGGATGCCCTGATCCAGGACGGGCGGGC
CGATACGCTCATCGCCTACCTGGAATCGCTGGCGGGCGGCGCTGAGGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References