Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelE-RelB |
| Location | 1849260..1849819 | Replicon | chromosome |
| Accession | NZ_CP016224 | ||
| Organism | Vibrio alginolyticus strain ZJ-T | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A347UR22 |
| Locus tag | BAU10_RS08265 | Protein ID | WP_005398411.1 |
| Coordinates | 1849541..1849819 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A347UR21 |
| Locus tag | BAU10_RS08260 | Protein ID | WP_005398409.1 |
| Coordinates | 1849260..1849544 (+) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BAU10_RS08230 | 1844758..1845288 | - | 531 | WP_054702813.1 | hypothetical protein | - |
| BAU10_RS24535 | 1845317..1845442 | - | 126 | WP_082240152.1 | DUF3265 domain-containing protein | - |
| BAU10_RS08235 | 1845432..1845836 | - | 405 | WP_065274605.1 | hypothetical protein | - |
| BAU10_RS24540 | 1845875..1846081 | - | 207 | WP_081097955.1 | DUF3265 domain-containing protein | - |
| BAU10_RS25625 | 1845990..1846568 | - | 579 | WP_065274606.1 | hypothetical protein | - |
| BAU10_RS24545 | 1846595..1846708 | - | 114 | WP_082240171.1 | DUF3265 domain-containing protein | - |
| BAU10_RS08245 | 1846908..1847864 | + | 957 | WP_033906599.1 | IS110 family transposase | - |
| BAU10_RS08255 | 1848458..1849207 | - | 750 | WP_082240153.1 | DUF3265 domain-containing protein | - |
| BAU10_RS08260 | 1849260..1849544 | + | 285 | WP_005398409.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| BAU10_RS08265 | 1849541..1849819 | + | 279 | WP_005398411.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
| BAU10_RS24550 | 1849848..1849976 | - | 129 | WP_077200588.1 | DUF3265 domain-containing protein | - |
| BAU10_RS08270 | 1850572..1850784 | - | 213 | WP_025553613.1 | hypothetical protein | - |
| BAU10_RS24555 | 1851294..1851410 | - | 117 | WP_080960423.1 | DUF3265 domain-containing protein | - |
| BAU10_RS08275 | 1852023..1852742 | - | 720 | WP_065274609.1 | hypothetical protein | - |
| BAU10_RS24560 | 1852775..1852867 | - | 93 | WP_072612521.1 | DUF3265 domain-containing protein | - |
| BAU10_RS08280 | 1852890..1853540 | - | 651 | WP_029804518.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1825012..1859021 | 34009 | |
| - | flank | IS/Tn | - | - | 1853884..1854840 | 956 | |
| - | inside | Integron | - | - | 1839402..1857273 | 17871 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10891.57 Da Isoelectric Point: 4.3430
>T64341 WP_005398411.1 NZ_CP016224:1849541-1849819 [Vibrio alginolyticus]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEGDIIRVM
RVLHQKQKFPTD
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEGDIIRVM
RVLHQKQKFPTD
Download Length: 279 bp
>T64341 NZ_CP016224:1849541-1849819 [Vibrio alginolyticus]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTAATGGGTGTACAACGAGATGGCA
TCCGCGGACGATTGCTCATTATTCCTGAGATTTCGATGATTGTATCTTACTGGGTTGAGGGCGATATCATCCGAGTTATG
CGTGTACTACACCAGAAACAAAAATTCCCTACGGATTGA
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTAATGGGTGTACAACGAGATGGCA
TCCGCGGACGATTGCTCATTATTCCTGAGATTTCGATGATTGTATCTTACTGGGTTGAGGGCGATATCATCCGAGTTATG
CGTGTACTACACCAGAAACAAAAATTCCCTACGGATTGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 11069.40 Da Isoelectric Point: 9.2167
>AT64341 WP_005398409.1 NZ_CP016224:1849260-1849544 [Vibrio alginolyticus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ
Download Length: 285 bp
>AT64341 NZ_CP016224:1849260-1849544 [Vibrio alginolyticus]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCTTAGCTCAACAAATGGCTGAGAGCCAAGGTCGAAC
TCTAAGTGATGCTTGCCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCTGTTTTCGTTGAGCACCAAACGGCTAAGTCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCTTAGCTCAACAAATGGCTGAGAGCCAAGGTCGAAC
TCTAAGTGATGCTTGCCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCTGTTTTCGTTGAGCACCAAACGGCTAAGTCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A347UR22 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A347UR21 |