Detailed information of TA system TA064339

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): phd-doc/Doc(toxin)
• Location: 41029..41594
• Replicon: chromosome
• Accession: NZ_CP016224
• Organism: Vibrio alginolyticus strain ZJ-T

Toxin (Protein)

• Gene name: doc
• Uniprot ID: -
• Locus tag: BAU10_RS00200
• Protein ID: WP_005397969.1
• Coordinates: 41199..41594 (+)
• Length: 132 a.a.

Antitoxin (Protein)

• Gene name: phd
• Uniprot ID: -
• Locus tag: BAU10_RS00195
• Protein ID: WP_005397970.1
• Coordinates: 41029..41199 (+)
• Length: 57 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BAU10_RS00175	37834..38109	+	276	WP_065274105.1	helix-turn-helix domain-containing protein	-
BAU10_RS00180	38102..39337	+	1236	WP_065275047.1	type II toxin-antitoxin system HipA family toxin	-
BAU10_RS00185	39380..39679	+	300	WP_065274106.1	hypothetical protein	-
BAU10_RS24995	40153..40314	+	162	WP_114139449.1	thrombospondin type 3 repeat-containing protein	-
BAU10_RS00190	40575..40811	+	237	WP_065274107.1	hypothetical protein	-
BAU10_RS00195	41029..41199	+	171	WP_005397970.1	hypothetical protein	Antitoxin
BAU10_RS00200	41199..41594	+	396	WP_005397969.1	type II toxin-antitoxin system death-on-curing family toxin	Toxin
BAU10_RS00205	42317..42736	+	420	Protein_39	IS110 family transposase	-
BAU10_RS00210	43624..45726	+	2103	WP_031780673.1	YjbH domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	42317..42772	455

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Death on curing protein (1-125)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 132 a.a.
• Molecular weight: 14240.33 Da
• Isoelectric Point: 3.7785

>T64339 WP_005397969.1 NZ_CP016224:41199-41594 [Vibrio alginolyticus]
MDIICFPFERVIEINSFILATEPGMQGEVDIPKLQGALGRIDNAIAYDGLEDVFDIASKYAASIAIAHALPDANKRTGLM
VALEYLSLNEFEIVIDNALLADAVRDLLLGVLTEADFADILYAQYTAGLEC

Nucleotide

• Length: 396 bp

>T64339 NZ_CP016224:41199-41594 [Vibrio alginolyticus]
ATGGATATCATCTGTTTTCCATTCGAGCGAGTGATTGAAATAAATTCGTTTATTTTAGCGACTGAGCCAGGTATGCAGGG
AGAGGTGGATATACCAAAGCTGCAAGGTGCATTGGGTCGAATTGACAATGCGATCGCGTATGATGGTCTGGAAGATGTTT
TTGATATTGCATCAAAGTATGCGGCAAGTATTGCCATCGCTCACGCCCTACCTGATGCAAATAAACGCACGGGGCTGATG
GTTGCGCTTGAATACTTATCACTTAATGAGTTTGAAATTGTCATCGACAACGCCTTACTTGCTGATGCCGTCAGAGATCT
TTTGCTTGGTGTATTAACCGAAGCGGATTTCGCGGATATTTTGTATGCACAATACACGGCGGGGCTTGAGTGTTGA

Antitoxin

Protein

• Length: 57 a.a.
• Molecular weight: 6314.48 Da
• Isoelectric Point: 11.4763

>AT64339 WP_005397970.1 NZ_CP016224:41029-41199 [Vibrio alginolyticus]
MSKDLSAYGVPQVKRPKVKATKQLDLSGMQGRQIVRSEAKLALRTHRKTFTKLADM

Nucleotide

• Length: 171 bp

>AT64339 NZ_CP016224:41029-41199 [Vibrio alginolyticus]
ATGAGCAAAGACTTGTCAGCCTATGGAGTGCCACAGGTAAAAAGACCGAAAGTAAAAGCGACCAAGCAGTTAGACTTGAG
TGGGATGCAGGGGCGTCAAATTGTGCGTTCTGAAGCCAAGTTAGCGCTAAGAACGCATCGTAAGACATTCACGAAATTAG
CGGATATGTGA