Detailed information of TA system TA064328

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1094789..1095320
• Replicon: chromosome
• Accession: NZ_CP016210
• Organism: Azoarcus olearius strain DQS-4

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: dqs_RS05220
• Protein ID: WP_065339863.1
• Coordinates: 1095027..1095320 (+)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A4Y6KPG1
• Locus tag: dqs_RS05215
• Protein ID: WP_065339862.1
• Coordinates: 1094789..1095037 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
dqs_RS05190	1089995..1091713	+	1719	WP_065339858.1	cation acetate symporter	-
dqs_RS05195	1091827..1092498	-	672	WP_065339859.1	response regulator transcription factor	-
dqs_RS05205	1092955..1094394	+	1440	WP_065339860.1	site-specific integrase	-
dqs_RS05210	1094391..1094801	+	411	WP_065339861.1	hypothetical protein	-
dqs_RS05215	1094789..1095037	+	249	WP_065339862.1	plasmid stabilization protein	Antitoxin
dqs_RS05220	1095027..1095320	+	294	WP_065339863.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
dqs_RS05225	1095451..1096953	-	1503	WP_065339864.1	Fic family protein	-
dqs_RS20660	1097230..1099182	-	1953	WP_157108146.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 10923.69 Da
• Isoelectric Point: 10.0967

>T64328 WP_065339863.1 NZ_CP016210:1095027-1095320 [Azoarcus olearius]
MNYELGFIDEALAEWRTLDGSVRAQFKTLLAERLKKLPGPAAKLGGHPDRYEIALRRGGHRLVYEMRGPQLVVVIAGGKW
DRSAVYKVADGRCPMER

Nucleotide

• Length: 294 bp

>T64328 NZ_CP016210:1095027-1095320 [Azoarcus olearius]
ATGAACTATGAGCTTGGCTTCATCGATGAGGCCCTGGCCGAGTGGAGAACACTCGACGGCAGCGTCCGGGCGCAGTTCAA
GACGCTGCTGGCCGAGCGTCTGAAAAAGCTGCCCGGGCCGGCTGCCAAGCTCGGGGGGCATCCGGACCGCTATGAAATAG
CGCTCCGCCGGGGTGGGCACCGACTGGTCTATGAGATGCGGGGCCCGCAACTGGTTGTGGTCATCGCGGGCGGCAAGTGG
GATCGCAGTGCGGTGTACAAGGTGGCGGATGGACGCTGCCCAATGGAGCGCTGA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 8871.37 Da
• Isoelectric Point: 6.9755

>AT64328 WP_065339862.1 NZ_CP016210:1094789-1095037 [Azoarcus olearius]
MAHLILAETTATVSELKRNPMGTVAAGEGMPVAILNRSAPVFYCVPAKAYVALMDRLKDLELNLLADTRASQRVTRGTLD
EL

Nucleotide

• Length: 249 bp

>AT64328 NZ_CP016210:1094789-1095037 [Azoarcus olearius]
ATGGCACACCTGATTCTGGCGGAAACCACTGCGACCGTCTCCGAACTGAAGCGCAACCCCATGGGTACGGTTGCAGCGGG
GGAGGGCATGCCCGTTGCAATTCTGAATCGCAGCGCGCCTGTGTTCTATTGTGTTCCTGCAAAGGCCTACGTAGCGCTGA
TGGACCGCTTGAAGGACCTGGAGCTCAATCTCCTTGCCGATACGCGTGCCAGCCAGCGCGTTACCCGGGGGACGCTCGAT
GAACTATGA

Structures

Antitoxin

• AlphaFold DB: A0A4Y6KPG1