Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2340283..2340554 Replicon chromosome
Accession NZ_CP016182
Organism Escherichia coli strain EC590

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2340413..2340516 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2340283..2340554 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BAY41_RS11840 2336839..2337501 - 663 WP_000944256.1 exodeoxyribonuclease X -
BAY41_RS11845 2337525..2338181 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
BAY41_RS11850 2338283..2338513 - 231 WP_000916763.1 DNA polymerase III subunit theta -
BAY41_RS11855 2338652..2339026 + 375 WP_000168747.1 CopC domain-containing protein YobA -
BAY41_RS11860 2339030..2339901 + 872 Protein_2156 copper homeostasis membrane protein CopD -
BAY41_RS11865 2339914..2340255 + 342 WP_000976476.1 YebY family protein -
- 2340283..2340554 - 272 - - Antitoxin
- 2340413..2340516 + 104 - - Toxin
BAY41_RS11870 2340651..2341307 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
BAY41_RS11875 2341308..2341499 - 192 WP_000457842.1 YebW family protein -
BAY41_RS11880 2341604..2341840 - 237 WP_001295499.1 DUF1480 family protein -
BAY41_RS11885 2341958..2343397 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T64312 NZ_CP016182:2340413-2340516 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT64312 NZ_CP016182:c2340554-2340283 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References