Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 473002..473567 Replicon chromosome
Accession NZ_CP016180
Organism Pasteurella skyensis strain 95A1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A6B44_RS02240 Protein ID WP_090922539.1
Coordinates 473283..473567 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag A6B44_RS02235 Protein ID WP_090922537.1
Coordinates 473002..473286 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6B44_RS02210 468034..468966 + 933 WP_090922527.1 GTP-binding protein -
A6B44_RS02215 469032..469829 + 798 WP_090922529.1 3'(2'),5'-bisphosphate nucleotidase CysQ -
A6B44_RS02220 469896..471380 + 1485 WP_090922531.1 glucose-6-phosphate dehydrogenase -
A6B44_RS02225 471386..472087 + 702 WP_090922533.1 6-phosphogluconolactonase -
A6B44_RS02230 472175..472849 + 675 WP_090922535.1 hypothetical protein -
A6B44_RS02235 473002..473286 + 285 WP_090922537.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
A6B44_RS02240 473283..473567 + 285 WP_090922539.1 type II toxin-antitoxin system YafQ family toxin Toxin
A6B44_RS02245 473751..475199 + 1449 WP_090922541.1 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase -
A6B44_RS02250 475528..476067 + 540 WP_090922543.1 translation initiation factor IF-3 -
A6B44_RS02255 476234..476431 + 198 WP_090922545.1 50S ribosomal protein L35 -
A6B44_RS02260 476486..476839 + 354 WP_090922547.1 50S ribosomal protein L20 -
A6B44_RS02265 476938..477234 - 297 WP_090922549.1 YceK/YidQ family lipoprotein -
A6B44_RS02270 477241..478260 - 1020 WP_090922551.1 aldose 1-epimerase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(5-94)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(8-74)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11275.12 Da        Isoelectric Point: 9.3106

>T64303 WP_090922539.1 NZ_CP016180:473283-473567 [Pasteurella skyensis]
MMIKKITFSKEFKRDLINISKKAPEILVSDRYIEVIYLLQNNQPLPEKYKDHSLSGNMDNYRDCHIFNDLVLIYRIEDKH
LYLSRIGTHSQVFK

Download         Length: 285 bp

>T64303 NZ_CP016180:473283-473567 [Pasteurella skyensis]
ATGATGATTAAAAAGATAACTTTTTCCAAAGAATTTAAACGTGATTTGATCAATATCTCAAAAAAAGCACCTGAAATTTT
AGTCAGTGATAGATATATTGAAGTCATTTATCTTTTGCAGAATAATCAGCCGTTACCAGAAAAATATAAAGATCATTCGT
TAAGTGGGAATATGGATAATTATAGAGATTGCCATATTTTTAATGATTTAGTTTTAATTTACAGAATTGAAGATAAGCAT
TTATATCTTTCTCGTATTGGTACACATTCACAGGTTTTTAAATAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10550.00 Da        Isoelectric Point: 5.0052

>AT64303 WP_090922537.1 NZ_CP016180:473002-473286 [Pasteurella skyensis]
MVAVNNSAFSFRVPEKVKTQAFDVIAQYGLTPSQVMNMFLNEIAHTKTIPVNLDYHQPNARTLRAIEEIESGQGQTITLS
DDENLVDVLNRLCK

Download         Length: 285 bp

>AT64303 NZ_CP016180:473002-473286 [Pasteurella skyensis]
ATGGTAGCAGTAAATAATTCAGCATTTAGTTTTAGAGTACCTGAAAAAGTGAAAACTCAAGCGTTTGACGTGATTGCTCA
ATATGGATTAACACCTTCACAGGTAATGAATATGTTTTTAAATGAAATCGCTCATACTAAAACCATTCCTGTGAATTTGG
ATTATCATCAACCGAATGCGAGAACCTTAAGGGCAATAGAAGAAATTGAAAGTGGACAAGGACAGACCATCACACTTTCT
GATGATGAAAATTTGGTAGACGTATTGAATAGACTGTGTAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References