Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hipBA/HipA-couple_hipB |
Location | 5808189..5809782 | Replicon | chromosome |
Accession | NZ_CP016171 | ||
Organism | Bordetella bronchialis strain AU17976 |
Toxin (Protein)
Gene name | hipA | Uniprot ID | A0A193G4C9 |
Locus tag | BAU08_RS25730 | Protein ID | WP_066672336.1 |
Coordinates | 5808442..5809782 (+) | Length | 447 a.a. |
Antitoxin (Protein)
Gene name | hipB | Uniprot ID | A0A193G380 |
Locus tag | BAU08_RS25725 | Protein ID | WP_066672334.1 |
Coordinates | 5808189..5808440 (+) | Length | 84 a.a. |
Genomic Context
Location: 5807202..5808047 (846 bp)
Type: Others
Protein ID: WP_066672332.1
Type: Others
Protein ID: WP_066672332.1
Location: 5808189..5808440 (252 bp)
Type: Antitoxin
Protein ID: WP_066672334.1
Type: Antitoxin
Protein ID: WP_066672334.1
Location: 5808442..5809782 (1341 bp)
Type: Toxin
Protein ID: WP_066672336.1
Type: Toxin
Protein ID: WP_066672336.1
Location: 5810845..5811840 (996 bp)
Type: Others
Protein ID: WP_066672344.1
Type: Others
Protein ID: WP_066672344.1
Location: 5811837..5813237 (1401 bp)
Type: Others
Protein ID: WP_066672346.1
Type: Others
Protein ID: WP_066672346.1
Location: 5813490..5814464 (975 bp)
Type: Others
Protein ID: WP_066672348.1
Type: Others
Protein ID: WP_066672348.1
Location: 5803833..5804165 (333 bp)
Type: Others
Protein ID: WP_066672324.1
Type: Others
Protein ID: WP_066672324.1
Location: 5804162..5804956 (795 bp)
Type: Others
Protein ID: WP_066672326.1
Type: Others
Protein ID: WP_066672326.1
Location: 5804960..5805856 (897 bp)
Type: Others
Protein ID: WP_066672328.1
Type: Others
Protein ID: WP_066672328.1
Location: 5805938..5807002 (1065 bp)
Type: Others
Protein ID: WP_066672330.1
Type: Others
Protein ID: WP_066672330.1
Location: 5809832..5810701 (870 bp)
Type: Others
Protein ID: WP_066672340.1
Type: Others
Protein ID: WP_066672340.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BAU08_RS25700 | 5803833..5804165 | - | 333 | WP_066672324.1 | (2Fe-2S)-binding protein | - |
BAU08_RS25705 | 5804162..5804956 | - | 795 | WP_066672326.1 | ABC transporter permease | - |
BAU08_RS25710 | 5804960..5805856 | - | 897 | WP_066672328.1 | ABC transporter permease | - |
BAU08_RS25715 | 5805938..5807002 | - | 1065 | WP_066672330.1 | ABC transporter ATP-binding protein | - |
BAU08_RS25720 | 5807202..5808047 | + | 846 | WP_066672332.1 | IclR family transcriptional regulator | - |
BAU08_RS25725 | 5808189..5808440 | + | 252 | WP_066672334.1 | helix-turn-helix domain-containing protein | Antitoxin |
BAU08_RS25730 | 5808442..5809782 | + | 1341 | WP_066672336.1 | type II toxin-antitoxin system HipA family toxin | Toxin |
BAU08_RS25735 | 5809832..5810701 | - | 870 | WP_066672340.1 | LysR family transcriptional regulator | - |
BAU08_RS25740 | 5810845..5811840 | + | 996 | WP_066672344.1 | tripartite tricarboxylate transporter substrate binding protein | - |
BAU08_RS25745 | 5811837..5813237 | + | 1401 | WP_066672346.1 | MmgE/PrpD family protein | - |
BAU08_RS25750 | 5813490..5814464 | + | 975 | WP_066672348.1 | tripartite tricarboxylate transporter substrate binding protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 447 a.a. Molecular weight: 48607.54 Da Isoelectric Point: 7.0003
>T64283 WP_066672336.1 NZ_CP016171:5808442-5809782 [Bordetella bronchialis]
MARRLHRLAIWMNGTHVGLWAEEAGVSSFQYSPAWLDDPAGRPLSLSLPFRLGNAPYKGAVVHDFFDNLLPDSDAIRRRL
AQHHRADSAAPFDLLAVLGRDCVGAVQLLPPGEVPTGLDHIEADPLNDADIARILKAAVSGAPLGHEDRTADLRLSIAGA
QEKTALLRHQGQWLRPRGSTPTTHILKLPMGLVGAMQADMHASVENEWLCSKLAAAYGLPVAHCDMARFEDQKALVVERF
DRRFTDTGTIVRLPQEDMCQAMGVSPLRKYQADGGPGITAIIRGVLDSSEREEDVRAFYKAQMFFWMLAATDGHAKNFSI
ALLAGGRYHATPLYDILSAHPIIGNKRAQLAPQRAKLAMGVRGSGGLHYRLAEIRRRHWYTQAAEAGLDKSMVDDIIGEL
VEATEPAIEHAAALLPPGFPAHVADAVFAGLRAQRDKLVSQANDPA
MARRLHRLAIWMNGTHVGLWAEEAGVSSFQYSPAWLDDPAGRPLSLSLPFRLGNAPYKGAVVHDFFDNLLPDSDAIRRRL
AQHHRADSAAPFDLLAVLGRDCVGAVQLLPPGEVPTGLDHIEADPLNDADIARILKAAVSGAPLGHEDRTADLRLSIAGA
QEKTALLRHQGQWLRPRGSTPTTHILKLPMGLVGAMQADMHASVENEWLCSKLAAAYGLPVAHCDMARFEDQKALVVERF
DRRFTDTGTIVRLPQEDMCQAMGVSPLRKYQADGGPGITAIIRGVLDSSEREEDVRAFYKAQMFFWMLAATDGHAKNFSI
ALLAGGRYHATPLYDILSAHPIIGNKRAQLAPQRAKLAMGVRGSGGLHYRLAEIRRRHWYTQAAEAGLDKSMVDDIIGEL
VEATEPAIEHAAALLPPGFPAHVADAVFAGLRAQRDKLVSQANDPA
Download Length: 1341 bp
>T64283 NZ_CP016171:5808442-5809782 [Bordetella bronchialis]
ATGGCCCGAAGGCTGCACCGCCTGGCCATCTGGATGAACGGCACGCACGTCGGCCTTTGGGCGGAGGAGGCCGGCGTGTC
GTCGTTCCAATACAGCCCGGCATGGCTGGACGATCCGGCGGGGCGCCCGCTTTCGCTGTCCCTTCCCTTCCGCCTGGGCA
ACGCGCCCTACAAGGGAGCGGTCGTCCACGATTTCTTCGACAATCTTCTGCCCGACAGCGACGCGATCCGGCGCAGGCTG
GCCCAACACCACCGCGCCGACAGCGCAGCCCCCTTCGACCTCTTGGCGGTACTGGGCCGCGACTGCGTGGGCGCCGTGCA
ATTGCTGCCGCCCGGCGAAGTCCCGACCGGCCTGGACCATATCGAAGCCGACCCGCTAAACGATGCGGATATCGCGCGGA
TCCTGAAAGCCGCGGTCAGCGGCGCACCGCTGGGCCACGAGGACCGGACCGCCGATCTGCGCCTGTCCATCGCGGGCGCC
CAGGAAAAAACGGCCCTGCTGCGCCACCAGGGGCAGTGGCTGCGCCCGCGCGGCAGCACGCCCACCACCCATATCCTGAA
ATTGCCGATGGGACTGGTCGGCGCGATGCAGGCGGACATGCATGCCTCCGTGGAAAACGAATGGTTGTGCTCCAAGCTGG
CGGCGGCCTACGGGCTGCCGGTGGCCCATTGCGACATGGCTCGTTTCGAGGACCAGAAGGCCCTGGTGGTGGAGCGCTTC
GACCGCCGTTTCACGGATACCGGCACCATCGTGCGCCTGCCCCAGGAAGACATGTGCCAGGCCATGGGCGTGTCGCCGTT
GCGCAAATACCAGGCGGACGGCGGCCCGGGCATAACGGCCATCATCCGCGGCGTGCTGGATTCATCCGAACGCGAAGAAG
ACGTGCGCGCCTTCTACAAGGCACAGATGTTCTTCTGGATGCTGGCCGCCACCGATGGGCACGCCAAGAACTTCAGCATC
GCGCTGTTGGCCGGCGGCCGCTACCATGCGACGCCGCTATACGACATTCTTTCCGCGCACCCCATCATCGGCAACAAGCG
CGCGCAATTGGCGCCGCAGCGCGCCAAGCTGGCCATGGGGGTGCGGGGATCCGGCGGGCTGCATTACCGGCTGGCGGAAA
TCCGCCGGCGGCACTGGTACACGCAGGCGGCCGAGGCGGGGCTGGACAAAAGCATGGTCGACGACATCATCGGCGAATTG
GTGGAGGCCACCGAGCCCGCCATCGAACACGCCGCGGCCCTGCTGCCGCCAGGTTTCCCGGCGCATGTCGCGGATGCCGT
CTTCGCCGGCCTGCGCGCGCAGCGCGACAAGCTGGTCAGCCAGGCGAACGACCCGGCCTGA
ATGGCCCGAAGGCTGCACCGCCTGGCCATCTGGATGAACGGCACGCACGTCGGCCTTTGGGCGGAGGAGGCCGGCGTGTC
GTCGTTCCAATACAGCCCGGCATGGCTGGACGATCCGGCGGGGCGCCCGCTTTCGCTGTCCCTTCCCTTCCGCCTGGGCA
ACGCGCCCTACAAGGGAGCGGTCGTCCACGATTTCTTCGACAATCTTCTGCCCGACAGCGACGCGATCCGGCGCAGGCTG
GCCCAACACCACCGCGCCGACAGCGCAGCCCCCTTCGACCTCTTGGCGGTACTGGGCCGCGACTGCGTGGGCGCCGTGCA
ATTGCTGCCGCCCGGCGAAGTCCCGACCGGCCTGGACCATATCGAAGCCGACCCGCTAAACGATGCGGATATCGCGCGGA
TCCTGAAAGCCGCGGTCAGCGGCGCACCGCTGGGCCACGAGGACCGGACCGCCGATCTGCGCCTGTCCATCGCGGGCGCC
CAGGAAAAAACGGCCCTGCTGCGCCACCAGGGGCAGTGGCTGCGCCCGCGCGGCAGCACGCCCACCACCCATATCCTGAA
ATTGCCGATGGGACTGGTCGGCGCGATGCAGGCGGACATGCATGCCTCCGTGGAAAACGAATGGTTGTGCTCCAAGCTGG
CGGCGGCCTACGGGCTGCCGGTGGCCCATTGCGACATGGCTCGTTTCGAGGACCAGAAGGCCCTGGTGGTGGAGCGCTTC
GACCGCCGTTTCACGGATACCGGCACCATCGTGCGCCTGCCCCAGGAAGACATGTGCCAGGCCATGGGCGTGTCGCCGTT
GCGCAAATACCAGGCGGACGGCGGCCCGGGCATAACGGCCATCATCCGCGGCGTGCTGGATTCATCCGAACGCGAAGAAG
ACGTGCGCGCCTTCTACAAGGCACAGATGTTCTTCTGGATGCTGGCCGCCACCGATGGGCACGCCAAGAACTTCAGCATC
GCGCTGTTGGCCGGCGGCCGCTACCATGCGACGCCGCTATACGACATTCTTTCCGCGCACCCCATCATCGGCAACAAGCG
CGCGCAATTGGCGCCGCAGCGCGCCAAGCTGGCCATGGGGGTGCGGGGATCCGGCGGGCTGCATTACCGGCTGGCGGAAA
TCCGCCGGCGGCACTGGTACACGCAGGCGGCCGAGGCGGGGCTGGACAAAAGCATGGTCGACGACATCATCGGCGAATTG
GTGGAGGCCACCGAGCCCGCCATCGAACACGCCGCGGCCCTGCTGCCGCCAGGTTTCCCGGCGCATGTCGCGGATGCCGT
CTTCGCCGGCCTGCGCGCGCAGCGCGACAAGCTGGTCAGCCAGGCGAACGACCCGGCCTGA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9528.13 Da Isoelectric Point: 11.1412
>AT64283 WP_066672334.1 NZ_CP016171:5808189-5808440 [Bordetella bronchialis]
MDYPVRTLQQLRPILQGFRKAKGLTQAQLAARLGITQQSYAKLEAAPEKASFDRVFRILQMLRVELALRPMDQADRAVAR
SEW
MDYPVRTLQQLRPILQGFRKAKGLTQAQLAARLGITQQSYAKLEAAPEKASFDRVFRILQMLRVELALRPMDQADRAVAR
SEW
Download Length: 252 bp
>AT64283 NZ_CP016171:5808189-5808440 [Bordetella bronchialis]
ATGGACTATCCCGTCCGCACCCTCCAACAGCTACGACCCATCCTGCAAGGGTTCCGCAAGGCCAAAGGGCTGACCCAGGC
GCAACTGGCGGCCCGCCTCGGCATCACCCAGCAAAGCTATGCCAAGCTGGAAGCCGCCCCGGAAAAGGCCAGCTTCGACC
GGGTCTTCCGCATCCTGCAGATGCTGCGTGTCGAGCTTGCCCTGCGGCCCATGGACCAGGCGGATCGCGCCGTCGCCAGG
TCGGAGTGGTGA
ATGGACTATCCCGTCCGCACCCTCCAACAGCTACGACCCATCCTGCAAGGGTTCCGCAAGGCCAAAGGGCTGACCCAGGC
GCAACTGGCGGCCCGCCTCGGCATCACCCAGCAAAGCTATGCCAAGCTGGAAGCCGCCCCGGAAAAGGCCAGCTTCGACC
GGGTCTTCCGCATCCTGCAGATGCTGCGTGTCGAGCTTGCCCTGCGGCCCATGGACCAGGCGGATCGCGCCGTCGCCAGG
TCGGAGTGGTGA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A193G4C9 |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A193G380 |