Detailed information of TA system TA064265

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Xre(antitoxin)
• Location: 3824757..3825980
• Replicon: chromosome
• Accession: NZ_CP016162
• Organism: Pseudomonas alcaliphila JAB1

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: UYA_RS17760
• Protein ID: WP_075749143.1
• Coordinates: 3824757..3825509 (-)
• Length: 251 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: A0A550GF52
• Locus tag: UYA_RS17765
• Protein ID: WP_017675072.1
• Coordinates: 3825609..3825980 (-)
• Length: 124 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
UYA_RS17745	3821563..3822510	+	948	WP_075749139.1	alpha/beta fold hydrolase	-
UYA_RS17750	3822525..3823886	-	1362	WP_167371384.1	DNA recombination protein RmuC	-
UYA_RS17755	3824066..3824317	-	252	WP_017675070.1	sel1 repeat family protein	-
UYA_RS17760	3824757..3825509	-	753	WP_075749143.1	RES family NAD+ phosphorylase	Toxin
UYA_RS17765	3825609..3825980	-	372	WP_017675072.1	XRE family transcriptional regulator	Antitoxin
UYA_RS17770	3826113..3828668	+	2556	WP_075749145.1	YdbH domain-containing protein	-
UYA_RS17775	3828673..3828864	+	192	WP_017675074.1	YnbE family lipoprotein	-
UYA_RS17780	3828896..3829234	+	339	WP_017675075.1	YdbL family protein	-
UYA_RS17785	3829296..3829622	-	327	WP_013716756.1	Grx4 family monothiol glutaredoxin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (62-208)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (8-68)

Sequences

Toxin

Protein

• Length: 251 a.a.
• Molecular weight: 28381.34 Da
• Isoelectric Point: 7.4768

>T64265 WP_075749143.1 NZ_CP016162:c3825509-3824757 [Pseudomonas alcaliphila JAB1]
MDIWQLCDGERQVRPLRGKLLRMVESQAQVATLQLVDNLAEQALLEELLESSKPPLPEAAEPLHYLLKTPFRYPPLRWGS
RFGSVHEPSLFYAAQRLQTAMAEAAYYRFVLWNGMAVPPPSGRILSEHSTFEARYRVERGIQLQQPPFDQHGAVLAHPSD
YSVPQRLGTSMRAAGIQAFEYRSARCPDAGSNVALYVPSAFAEKRPRNLTAWLCETTSEYVAFKHAQTPDQPRLFHWEQF
LVQGQLPHPA

Nucleotide

• Length: 753 bp

>T64265 NZ_CP016162:c3825509-3824757 [Pseudomonas alcaliphila JAB1]
ATGGATATCTGGCAACTATGTGACGGCGAGCGACAGGTGCGACCGCTGCGCGGCAAGCTGTTGCGCATGGTGGAGAGCCA
GGCGCAGGTTGCGACCCTGCAACTGGTGGATAACCTGGCCGAACAGGCCCTGCTCGAGGAACTGCTCGAGAGCAGCAAAC
CGCCGCTGCCGGAGGCTGCCGAGCCACTGCACTATCTGCTGAAGACGCCGTTTCGTTATCCGCCGCTGCGTTGGGGCTCG
CGCTTCGGCAGCGTGCATGAACCCAGCCTGTTCTACGCCGCTCAGCGTCTGCAAACGGCGATGGCCGAGGCCGCCTACTA
CCGTTTCGTACTGTGGAACGGCATGGCCGTGCCGCCGCCCAGTGGCCGCATCCTCTCCGAGCATTCGACCTTCGAGGCGC
GTTACCGCGTCGAGCGCGGTATCCAGTTGCAACAGCCGCCTTTCGATCAACATGGTGCAGTGTTGGCTCACCCCAGCGAT
TACAGCGTGCCTCAGCGTCTCGGTACGTCGATGCGCGCGGCGGGCATTCAGGCTTTCGAGTACCGTTCGGCACGTTGTCC
TGACGCTGGCAGCAATGTGGCGCTCTACGTGCCGTCTGCGTTCGCGGAGAAGCGTCCGCGTAATCTGACGGCCTGGTTGT
GTGAAACCACGAGCGAGTACGTGGCCTTCAAACATGCGCAAACGCCGGATCAACCGCGGCTGTTTCACTGGGAGCAGTTT
CTGGTGCAGGGGCAATTGCCGCACCCCGCGTAA

Antitoxin

Protein

• Length: 124 a.a.
• Molecular weight: 13688.75 Da
• Isoelectric Point: 10.6604

>AT64265 WP_017675072.1 NZ_CP016162:c3825980-3825609 [Pseudomonas alcaliphila JAB1]
MSAVTRSQPDADAVLAKALLNTREQLGLTQQELADIVGVHRSAISRWNEQGGLRPQSKTGELALLLIRAYRALFALFGGN
QQDMRHFLRTENRHLAGIPLQQMSQVQGLVRVVEYLDAIRGKV

Nucleotide

• Length: 372 bp

>AT64265 NZ_CP016162:c3825980-3825609 [Pseudomonas alcaliphila JAB1]
ATGAGTGCTGTGACTCGCTCTCAGCCCGATGCCGATGCGGTACTGGCTAAAGCCCTGCTCAATACCCGTGAGCAACTGGG
GCTGACGCAGCAGGAGCTGGCCGACATCGTAGGCGTCCATCGCAGTGCCATCAGCCGCTGGAACGAGCAGGGCGGTTTGC
GTCCGCAGAGCAAGACCGGTGAGCTGGCGCTGTTGCTGATTCGCGCCTATCGCGCGCTGTTTGCCCTGTTTGGTGGCAAT
CAGCAGGACATGCGCCATTTCCTGCGTACCGAAAATCGCCATCTGGCAGGCATTCCGCTGCAGCAGATGAGTCAGGTGCA
GGGGCTGGTGCGTGTTGTCGAGTATCTGGACGCCATTCGCGGCAAGGTCTGA

Structures

Antitoxin

• AlphaFold DB: A0A550GF52