Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 827221..827762 Replicon chromosome
Accession NZ_CP016162
Organism Pseudomonas alcaliphila JAB1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag UYA_RS03650 Protein ID WP_075745425.1
Coordinates 827221..827517 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag UYA_RS03655 Protein ID WP_021487971.1
Coordinates 827505..827762 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
UYA_RS03630 823035..824042 + 1008 WP_075745419.1 cytochrome d ubiquinol oxidase subunit II -
UYA_RS03635 824239..824385 + 147 WP_004425073.1 DUF2474 domain-containing protein -
UYA_RS03640 824456..825898 + 1443 WP_075745421.1 TldD/PmbA family protein -
UYA_RS03645 825898..827217 + 1320 WP_075745423.1 Zn-dependent protease -
UYA_RS03650 827221..827517 - 297 WP_075745425.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
UYA_RS03655 827505..827762 - 258 WP_021487971.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
UYA_RS03660 827831..828955 - 1125 WP_075745427.1 class I SAM-dependent methyltransferase -
UYA_RS03665 829198..829974 + 777 WP_075745429.1 ferredoxin--NADP reductase -
UYA_RS03670 829975..831000 - 1026 WP_075751054.1 hemolysin family protein -
UYA_RS03675 831197..831445 + 249 WP_017678808.1 YdcH family protein -
UYA_RS03680 831514..831792 + 279 WP_021487976.1 DUF465 domain-containing protein -
UYA_RS03685 831868..832362 - 495 WP_045734043.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11420.26 Da        Isoelectric Point: 6.0752

>T64263 WP_075745425.1 NZ_CP016162:c827517-827221 [Pseudomonas alcaliphila JAB1]
MAEIVWTNTALEQLDDLAHYIALDKPDAARALVRRAVETVSRLADFPLSGRVPDELPHSMYREIIVPPCRIFYRYTDATV
FIIHIMREERVLRAHMLE

Download         Length: 297 bp

>T64263 NZ_CP016162:c827517-827221 [Pseudomonas alcaliphila JAB1]
ATGGCTGAAATAGTCTGGACGAACACCGCCCTCGAGCAGCTCGACGATCTCGCGCACTACATCGCCCTCGACAAACCGGA
CGCCGCGCGAGCGCTGGTCAGGAGGGCCGTTGAAACGGTTTCACGGTTAGCAGACTTTCCCCTGTCGGGCCGCGTTCCTG
ATGAGCTTCCACACTCCATGTACCGCGAAATCATCGTCCCGCCCTGCCGAATTTTCTACCGCTATACAGACGCAACGGTT
TTCATCATCCACATCATGCGAGAGGAGCGCGTGCTGCGCGCCCACATGCTCGAATGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9757.31 Da        Isoelectric Point: 7.3181

>AT64263 WP_021487971.1 NZ_CP016162:c827762-827505 [Pseudomonas alcaliphila JAB1]
MKVELVTNLKRQATKILADLHESKEPVLITEHGMPSAYLVDVDDYQFMQKRLALLDALARGERAVIEGNTLNHEQAKERL
SKWLK

Download         Length: 258 bp

>AT64263 NZ_CP016162:c827762-827505 [Pseudomonas alcaliphila JAB1]
ATGAAAGTCGAGCTGGTAACCAACCTGAAGCGACAGGCCACCAAGATTCTGGCCGACCTTCACGAGTCCAAAGAACCTGT
ACTGATCACCGAGCATGGAATGCCTTCGGCTTATCTGGTGGATGTCGATGACTACCAGTTCATGCAGAAGCGTCTTGCCC
TTCTGGATGCTCTGGCTCGCGGAGAACGTGCCGTAATCGAGGGCAACACCCTGAACCATGAGCAGGCCAAGGAAAGGCTG
AGCAAATGGCTGAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References