Detailed information of TA system TA064263

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-Phd
• Location: 827221..827762
• Replicon: chromosome
• Accession: NZ_CP016162
• Organism: Pseudomonas alcaliphila JAB1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: UYA_RS03650
• Protein ID: WP_075745425.1
• Coordinates: 827221..827517 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: UYA_RS03655
• Protein ID: WP_021487971.1
• Coordinates: 827505..827762 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
UYA_RS03630	823035..824042	+	1008	WP_075745419.1	cytochrome d ubiquinol oxidase subunit II	-
UYA_RS03635	824239..824385	+	147	WP_004425073.1	DUF2474 domain-containing protein	-
UYA_RS03640	824456..825898	+	1443	WP_075745421.1	TldD/PmbA family protein	-
UYA_RS03645	825898..827217	+	1320	WP_075745423.1	Zn-dependent protease	-
UYA_RS03650	827221..827517	-	297	WP_075745425.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
UYA_RS03655	827505..827762	-	258	WP_021487971.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
UYA_RS03660	827831..828955	-	1125	WP_075745427.1	class I SAM-dependent methyltransferase	-
UYA_RS03665	829198..829974	+	777	WP_075745429.1	ferredoxin--NADP reductase	-
UYA_RS03670	829975..831000	-	1026	WP_075751054.1	hemolysin family protein	-
UYA_RS03675	831197..831445	+	249	WP_017678808.1	YdcH family protein	-
UYA_RS03680	831514..831792	+	279	WP_021487976.1	DUF465 domain-containing protein	-
UYA_RS03685	831868..832362	-	495	WP_045734043.1	GNAT family N-acetyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11420.26 Da
• Isoelectric Point: 6.0752

>T64263 WP_075745425.1 NZ_CP016162:c827517-827221 [Pseudomonas alcaliphila JAB1]
MAEIVWTNTALEQLDDLAHYIALDKPDAARALVRRAVETVSRLADFPLSGRVPDELPHSMYREIIVPPCRIFYRYTDATV
FIIHIMREERVLRAHMLE

Nucleotide

• Length: 297 bp

>T64263 NZ_CP016162:c827517-827221 [Pseudomonas alcaliphila JAB1]
ATGGCTGAAATAGTCTGGACGAACACCGCCCTCGAGCAGCTCGACGATCTCGCGCACTACATCGCCCTCGACAAACCGGA
CGCCGCGCGAGCGCTGGTCAGGAGGGCCGTTGAAACGGTTTCACGGTTAGCAGACTTTCCCCTGTCGGGCCGCGTTCCTG
ATGAGCTTCCACACTCCATGTACCGCGAAATCATCGTCCCGCCCTGCCGAATTTTCTACCGCTATACAGACGCAACGGTT
TTCATCATCCACATCATGCGAGAGGAGCGCGTGCTGCGCGCCCACATGCTCGAATGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9757.31 Da
• Isoelectric Point: 7.3181

>AT64263 WP_021487971.1 NZ_CP016162:c827762-827505 [Pseudomonas alcaliphila JAB1]
MKVELVTNLKRQATKILADLHESKEPVLITEHGMPSAYLVDVDDYQFMQKRLALLDALARGERAVIEGNTLNHEQAKERL
SKWLK

Nucleotide

• Length: 258 bp

>AT64263 NZ_CP016162:c827762-827505 [Pseudomonas alcaliphila JAB1]
ATGAAAGTCGAGCTGGTAACCAACCTGAAGCGACAGGCCACCAAGATTCTGGCCGACCTTCACGAGTCCAAAGAACCTGT
ACTGATCACCGAGCATGGAATGCCTTCGGCTTATCTGGTGGATGTCGATGACTACCAGTTCATGCAGAAGCGTCTTGCCC
TTCTGGATGCTCTGGCTCGCGGAGAACGTGCCGTAATCGAGGGCAACACCCTGAACCATGAGCAGGCCAAGGAAAGGCTG
AGCAAATGGCTGAAATAG