Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4407925..4408070 Replicon chromosome
Accession NZ_CP016159
Organism Klebsiella pneumoniae strain TH1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4407961..4408063 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4407925..4408070 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BAU11_RS21530 4403055..4405115 + 2061 WP_004151449.1 oligopeptidase B -
BAU11_RS21535 4405119..4405778 - 660 WP_002911407.1 exodeoxyribonuclease X -
BAU11_RS21540 4405857..4406087 - 231 WP_002911406.1 DNA polymerase III subunit theta -
BAU11_RS21545 4406200..4406574 + 375 WP_004151448.1 CopC domain-containing protein YobA -
BAU11_RS21550 4406578..4407447 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
BAU11_RS21555 4407464..4407802 + 339 WP_002911404.1 YebY family protein -
- 4407925..4408070 - 146 - - Antitoxin
- 4407961..4408063 + 103 - - Toxin
BAU11_RS29010 4408438..4408581 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
BAU11_RS21565 4408686..4409654 - 969 WP_004151446.1 VirK/YbjX family protein -
BAU11_RS21570 4409811..4410464 + 654 WP_064081141.1 protein-serine/threonine phosphatase -
BAU11_RS21575 4410461..4410652 - 192 WP_002911395.1 YebW family protein -
BAU11_RS21580 4410750..4410989 - 240 WP_002911393.1 YebV family protein -
BAU11_RS21585 4411105..4412538 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T64252 NZ_CP016159:4407961-4408063 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT64252 NZ_CP016159:c4408070-4407925 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References