Detailed information of TA system TA064193

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-DnaT
• Location: 1759064..1759586
• Replicon: chromosome
• Accession: NZ_CP016044
• Organism: Edwardsiella piscicida strain S11-285

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: A9797_RS07885
• Protein ID: WP_069578568.1
• Coordinates: 1759064..1759345 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A411H7D8
• Locus tag: A9797_RS07890
• Protein ID: WP_069578569.1
• Coordinates: 1759335..1759586 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A9797_RS07870	1754450..1755226	+	777	WP_069578566.1	hypothetical protein	-
A9797_RS07875	1755219..1756880	+	1662	WP_069579645.1	terminase	-
A9797_RS07880	1756877..1758991	+	2115	WP_069578567.1	portal protein	-
A9797_RS07885	1759064..1759345	-	282	WP_069578568.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
A9797_RS07890	1759335..1759586	-	252	WP_069578569.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
A9797_RS07895	1759864..1760865	+	1002	WP_069578570.1	hypothetical protein	-
A9797_RS07900	1760883..1762121	+	1239	WP_069578572.1	N4-gp56 family major capsid protein	-
A9797_RS07905	1762180..1762575	+	396	WP_069578573.1	hypothetical protein	-
A9797_RS07910	1762617..1763060	+	444	WP_069578574.1	hypothetical protein	-
A9797_RS07915	1763060..1763641	+	582	WP_069578575.1	hypothetical protein	-
A9797_RS07920	1763641..1764303	+	663	WP_069578577.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1718715..1784211	65496

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10738.62 Da
• Isoelectric Point: 10.6993

>T64193 WP_069578568.1 NZ_CP016044:c1759345-1759064 [Edwardsiella piscicida]
MTYKLSFEKRALKEWKKLAPPIQSQLKKKLIERLENPHIPAARLSGRANRYKIKLRSSGYRLVYEVNDSEIILLVIAIGK
RADNDVYLAADGR

Nucleotide

• Length: 282 bp

>T64193 NZ_CP016044:c1759345-1759064 [Edwardsiella piscicida]
ATGACCTATAAACTGAGCTTTGAAAAGCGAGCCCTGAAAGAGTGGAAAAAACTGGCACCGCCCATTCAAAGCCAGTTGAA
AAAGAAACTGATCGAACGCCTGGAAAATCCACATATCCCGGCCGCCCGCTTAAGTGGGCGCGCTAACCGTTATAAAATAA
AATTACGATCTTCCGGTTATCGGTTAGTTTATGAAGTCAACGATAGCGAAATCATCCTGCTGGTGATCGCTATCGGTAAA
CGAGCCGATAACGACGTGTACCTAGCGGCAGACGGTCGTTAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9154.26 Da
• Isoelectric Point: 3.8074

>AT64193 WP_069578569.1 NZ_CP016044:c1759586-1759335 [Edwardsiella piscicida]
MAYQILTTTAASITDLKRNPMGTIAEGDGNAVAILNRNEPAFYCVPPELYAYYLELAENAALNRIADERLEDAEFVSVNI
DDL

Nucleotide

• Length: 252 bp

>AT64193 NZ_CP016044:c1759586-1759335 [Edwardsiella piscicida]
ATGGCATACCAAATTCTCACTACAACAGCCGCCAGTATTACCGATCTAAAACGCAATCCGATGGGTACCATTGCTGAGGG
TGACGGTAATGCCGTCGCAATCTTAAACCGGAATGAGCCGGCCTTTTACTGCGTTCCACCGGAGCTCTATGCTTACTACC
TGGAGCTGGCTGAAAATGCTGCTCTTAATCGTATCGCCGATGAGCGTCTAGAGGACGCTGAATTCGTCAGCGTAAATATC
GATGACCTATAA

Structures

Antitoxin

• AlphaFold DB: A0A411H7D8