Detailed information of TA system TA064170

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-DnaT
• Location: 1751761..1752283
• Replicon: chromosome
• Accession: NZ_CP016043
• Organism: Edwardsiella hoshinae strain ATCC 35051

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: A9798_RS07790
• Protein ID: WP_070244886.1
• Coordinates: 1751761..1752042 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: A9798_RS07795
• Protein ID: WP_070244887.1
• Coordinates: 1752032..1752283 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A9798_RS07775	1748488..1749259	+	772	Protein_1520	Rha family transcriptional regulator	-
A9798_RS07780	1749441..1750736	+	1296	WP_156774566.1	hypothetical protein	-
A9798_RS07785	1750858..1751676	+	819	WP_070244885.1	hypothetical protein	-
A9798_RS07790	1751761..1752042	-	282	WP_070244886.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
A9798_RS07795	1752032..1752283	-	252	WP_070244887.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1728611..1759810	31199

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10797.65 Da
• Isoelectric Point: 10.6993

>T64170 WP_070244886.1 NZ_CP016043:c1752042-1751761 [Edwardsiella hoshinae]
MTYKLSFEKRALKEWKKLAPPIQSQLKKKLIERLENPHVPAARLSGRANRYKIKLRASGYRLVYEVNDSEIILLVIAIGK
RADNEVYQTADSR

Nucleotide

• Length: 282 bp

>T64170 NZ_CP016043:c1752042-1751761 [Edwardsiella hoshinae]
ATGACCTATAAACTGAGCTTTGAAAAACGTGCCCTGAAAGAGTGGAAAAAGCTGGCACCGCCCATTCAAAGCCAGTTGAA
AAAGAAACTGATCGAACGCCTGGAAAACCCACATGTTCCAGCAGCACGCTTAAGCGGGCGCGCTAACCGTTATAAAATAA
AATTACGCGCTTCCGGTTACCGGCTCGTCTATGAGGTCAACGATAGCGAAATCATCCTGCTGGTGATCGCTATCGGCAAA
CGGGCCGATAACGAGGTATACCAGACGGCAGACAGCCGTTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9114.19 Da
• Isoelectric Point: 3.7550

>AT64170 WP_070244887.1 NZ_CP016043:c1752283-1752032 [Edwardsiella hoshinae]
MAYQILTTTAASITDLKRNPMGTVAEGDGNAVAILNRNEPAFYCVPPELYAYYLELAEDAALNRIADERLEDAEFVSVSI
DDL

Nucleotide

• Length: 252 bp

>AT64170 NZ_CP016043:c1752283-1752032 [Edwardsiella hoshinae]
ATGGCATACCAAATTCTCACGACCACCGCCGCCAGTATTACCGATCTGAAACGCAATCCGATGGGCACCGTTGCGGAGGG
TGACGGCAATGCCGTCGCAATCTTAAACCGCAATGAGCCGGCCTTTTACTGCGTGCCACCGGAACTCTACGCTTACTATC
TGGAACTGGCTGAAGATGCGGCGCTTAATCGTATCGCCGATGAGCGTCTGGAGGACGCTGAGTTTGTCAGCGTAAGTATC
GATGACCTATAA