Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 745..1270 Replicon plasmid pCFSAN001660
Accession NZ_CP016011
Organism Salmonella enterica subsp. enterica serovar Newport strain CFSAN001660

Toxin (Protein)


Gene name ccdB Uniprot ID I3VZQ7
Locus tag A8179_RS24565 Protein ID WP_001159874.1
Coordinates 745..1050 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID I3VZQ6
Locus tag A8179_RS24570 Protein ID WP_000813642.1
Coordinates 1052..1270 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A8179_RS24560 453..743 - 291 WP_001266178.1 hypothetical protein -
A8179_RS24565 745..1050 - 306 WP_001159874.1 type II toxin-antitoxin system toxin CcdB Toxin
A8179_RS24570 1052..1270 - 219 WP_000813642.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
A8179_RS24575 1980..2225 + 246 WP_000368362.1 hypothetical protein -
A8179_RS24580 2230..3192 + 963 WP_000169858.1 hypothetical protein -
A8179_RS24585 4860..5354 + 495 WP_000786171.1 hypothetical protein -
A8179_RS24590 5484..5981 + 498 WP_000526848.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..67730 67730


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 15030.03 Da        Isoelectric Point: 5.5500

>T64115 WP_001159874.1 NZ_CP016011:c1050-745 [Salmonella enterica subsp. enterica serovar Newport]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFF

Download         Length: 306 bp

>T64115 NZ_CP016011:c1050-745 [Salmonella enterica subsp. enterica serovar Newport]
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 10761.91 Da        Isoelectric Point: 5.5500

>AT64115 WP_000813642.1 NZ_CP016011:c1270-1052 [Salmonella enterica subsp. enterica serovar Newport]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 219 bp

>AT64115 NZ_CP016011:c1270-1052 [Salmonella enterica subsp. enterica serovar Newport]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A600Z065

Antitoxin

Source ID Structure
AlphaFold DB A0A600YYQ0

References