64013

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4922139..4922500 Replicon chromosome
Accession NZ_CP015972
Organism Xanthomonas citri pv. glycines str. 12-2

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag A9D66_RS22420 Protein ID WP_005914328.1
Coordinates 4922139..4922273 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag A9D66_RS22425 Protein ID WP_003486606.1
Coordinates 4922348..4922500 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A9D66_RS22400 4917290..4918981 - 1692 WP_016850771.1 M20/M25/M40 family metallo-hydrolase -
A9D66_RS22405 4919173..4920207 - 1035 WP_016850772.1 MBL fold metallo-hydrolase -
A9D66_RS22410 4920246..4921535 - 1290 WP_016850773.1 tryptophan--tRNA ligase -
A9D66_RS22415 4921703..4921912 - 210 WP_003486601.1 CsbD family protein -
A9D66_RS22420 4922139..4922273 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
A9D66_RS22425 4922348..4922500 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
A9D66_RS22430 4922607..4923530 - 924 WP_003486608.1 arginase -
A9D66_RS22435 4923851..4924303 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
A9D66_RS22440 4924367..4924726 + 360 WP_003486613.1 hypothetical protein -
A9D66_RS22445 4924823..4925740 + 918 WP_016850774.1 hypothetical protein -
A9D66_RS22450 4925737..4926279 + 543 WP_003486615.1 GTPase -
A9D66_RS22460 4926717..4927400 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T64013 WP_005914328.1 NZ_CP015972:c4922273-4922139 [Xanthomonas citri pv. glycines str. 12-2]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T64013 NZ_CP015972:c4922273-4922139 [Xanthomonas citri pv. glycines str. 12-2]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGTTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT64013 WP_003486606.1 NZ_CP015972:c4922500-4922348 [Xanthomonas citri pv. glycines str. 12-2]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT64013 NZ_CP015972:c4922500-4922348 [Xanthomonas citri pv. glycines str. 12-2]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References