Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 3382187..3382774 Replicon chromosome
Accession NZ_CP015971
Organism Arachidicoccus sp. BS20

Toxin (Protein)


Gene name PumA Uniprot ID A0A191TP02
Locus tag A9P82_RS14705 Protein ID WP_066209135.1
Coordinates 3382475..3382774 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A191TP05
Locus tag A9P82_RS14700 Protein ID WP_066209129.1
Coordinates 3382187..3382471 (-) Length 95 a.a.

Genomic Context

A9P82_RS14680A9P82_RS14685A9P82_RS14690A9P82_RS14695A9P82_RS14700A9P82_RS14705A9P82_RS14710A9P82_RS14715A9P82_RS14720A9P82_RS14725A9P82_RS14730
Location: 3377910..3378626 (717 bp)
Type: Others
Protein ID: WP_066209118.1
Location: 3378626..3379795 (1170 bp)
Type: Others
Protein ID: WP_066209121.1
Location: 3379850..3380659 (810 bp)
Type: Others
Protein ID: WP_066209125.1
Location: 3380821..3382056 (1236 bp)
Type: Others
Protein ID: WP_066209127.1
Location: 3382187..3382471 (285 bp)
Type: Antitoxin
Protein ID: WP_066209129.1
Location: 3382475..3382774 (300 bp)
Type: Toxin
Protein ID: WP_066209135.1
Location: 3383291..3383755 (465 bp)
Type: Others
Protein ID: WP_156522710.1
Location: 3383979..3384818 (840 bp)
Type: Others
Protein ID: WP_066209140.1
Location: 3385010..3385645 (636 bp)
Type: Others
Protein ID: WP_082915373.1
Location: 3385666..3386238 (573 bp)
Type: Others
Protein ID: WP_066209143.1
Location: 3386346..3387566 (1221 bp)
Type: Others
Protein ID: WP_066209146.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
A9P82_RS146803377910..3378626+717WP_066209118.1LamB/YcsF family protein-
A9P82_RS146853378626..3379795+1170WP_066209121.1divalent metal cation transporter-
A9P82_RS146903379850..3380659+810WP_066209125.1type I methionyl aminopeptidase-
A9P82_RS146953380821..3382056+1236WP_066209127.1NAD(P)/FAD-dependent oxidoreductase-
A9P82_RS147003382187..3382471-285WP_066209129.1putative addiction module antidote proteinAntitoxin
A9P82_RS147053382475..3382774-300WP_066209135.1type II toxin-antitoxin system RelE/ParE family toxinToxin
A9P82_RS147103383291..3383755-465WP_156522710.1hypothetical protein-
A9P82_RS147153383979..3384818-840WP_066209140.1class I SAM-dependent methyltransferase-
A9P82_RS147203385010..3385645-636WP_082915373.1dihydrofolate reductase family protein-
A9P82_RS147253385666..3386238-573WP_066209143.1dihydrofolate reductase family protein-
A9P82_RS147303386346..3387566-1221WP_066209146.1site-specific DNA-methyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-98)

Antitoxin

Uncharacterized protein HI1420

(3-91)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11741.75 Da        Isoelectric Point: 10.2395

>T64011 WP_066209135.1 NZ_CP015971:c3382774-3382475 [Arachidicoccus sp. BS20]
MYFIEKTAEFDKWLRRLKDLRAKAKILFRIQKLETEEHFGDCKSVGNGISELKINYAKGYRIYFRETDGKIIILLIGGDK
STQQKDIEKAKQIWDKLKK

Download         Length: 300 bp

>T64011 NZ_CP015971:c3382774-3382475 [Arachidicoccus sp. BS20]
ATGTACTTTATTGAAAAAACAGCGGAATTTGACAAGTGGTTAAGAAGATTAAAGGATTTACGAGCAAAAGCAAAAATTTT
GTTTAGAATCCAAAAATTGGAAACCGAAGAACATTTCGGAGATTGTAAATCTGTCGGAAACGGCATTAGTGAATTAAAAA
TTAACTACGCAAAAGGTTATAGAATTTATTTCAGAGAAACAGACGGAAAAATTATAATTCTGCTTATAGGCGGCGATAAA
TCAACACAACAAAAAGACATTGAGAAAGCAAAACAAATTTGGGATAAATTAAAAAAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10105.53 Da        Isoelectric Point: 4.2412

>AT64011 WP_066209129.1 NZ_CP015971:c3382471-3382187 [Arachidicoccus sp. BS20]
METSKFDIADYLDNNEMIAEYLNTVIEEGNDADIINAIGNIAKAIGMTKIAEETGLSRPSLYKALSDGAKPQFTTIMKVL
KAVGGQIQVNPISA

Download         Length: 285 bp

>AT64011 NZ_CP015971:c3382471-3382187 [Arachidicoccus sp. BS20]
ATGGAAACTTCAAAATTTGACATAGCAGATTATTTAGACAACAACGAAATGATTGCGGAATATCTTAACACGGTTATAGA
AGAAGGCAATGATGCTGATATAATTAATGCTATTGGAAATATTGCAAAAGCAATCGGGATGACAAAAATTGCAGAAGAAA
CAGGTCTAAGCCGACCAAGTCTATACAAAGCGCTGTCCGACGGAGCAAAACCTCAATTTACAACTATAATGAAAGTTTTG
AAAGCCGTTGGCGGACAAATACAGGTTAATCCAATAAGCGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A191TP02

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A191TP05

References