Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 6873513..6873966 Replicon chromosome
Accession NZ_CP015878
Organism Pseudomonas citronellolis strain SJTE-3

Toxin (Protein)


Gene name relE Uniprot ID A0A1A9KKA1
Locus tag A9C11_RS29920 Protein ID WP_064584771.1
Coordinates 6873691..6873966 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1A9KKI2
Locus tag A9C11_RS29915 Protein ID WP_064584770.1
Coordinates 6873513..6873704 (+) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A9C11_RS29890 6870221..6871288 + 1068 WP_064584767.1 A/G-specific adenine glycosylase -
A9C11_RS29895 6871285..6871557 + 273 WP_064584768.1 oxidative damage protection protein -
A9C11_RS29905 6871806..6872921 + 1116 WP_064585170.1 site-specific integrase -
A9C11_RS29910 6873076..6873486 + 411 WP_064584769.1 hypothetical protein -
A9C11_RS29915 6873513..6873704 + 192 WP_064584770.1 hypothetical protein Antitoxin
A9C11_RS29920 6873691..6873966 + 276 WP_064584771.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A9C11_RS34655 6874411..6874629 - 219 WP_082936883.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
A9C11_RS35705 6874676..6875170 - 495 WP_157763354.1 hypothetical protein -
A9C11_RS35710 6875979..6876314 + 336 WP_157763355.1 hypothetical protein -
A9C11_RS29930 6876315..6878570 - 2256 WP_064584773.1 DotA/TraY family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 6873076..6882872 9796


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10197.68 Da        Isoelectric Point: 6.3214

>T63848 WP_064584771.1 NZ_CP015878:6873691-6873966 [Pseudomonas citronellolis]
VLPVKWGHEALDDLVEIIDYIEQYNPIAAASLHRHIVAAAEGLSTIPYGFRPGRVPGTREIVVHPNYLVVYRVGDTAVDV
LRVLHARQEYP

Download         Length: 276 bp

>T63848 NZ_CP015878:6873691-6873966 [Pseudomonas citronellolis]
GTGCTACCCGTTAAGTGGGGCCACGAGGCCCTGGACGACCTGGTCGAGATCATCGACTACATCGAGCAATACAACCCTAT
CGCCGCCGCATCATTGCATCGCCACATCGTCGCCGCCGCCGAAGGCCTGTCAACAATCCCCTACGGTTTCCGGCCCGGCC
GCGTGCCGGGCACCCGGGAAATCGTCGTGCACCCCAACTACCTGGTGGTCTACCGGGTCGGCGATACCGCCGTCGACGTG
CTGCGTGTCTTGCACGCCCGCCAGGAATACCCCTAA

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7370.27 Da        Isoelectric Point: 8.7082

>AT63848 WP_064584770.1 NZ_CP015878:6873513-6873704 [Pseudomonas citronellolis]
MAKLSPIVSEFETDEQAASYDRWFRARVQAALDDPRPSIPHDEAMAQVERRLEDKRKARRATR

Download         Length: 192 bp

>AT63848 NZ_CP015878:6873513-6873704 [Pseudomonas citronellolis]
ATGGCCAAGCTTTCCCCCATCGTGTCCGAGTTCGAGACAGACGAGCAGGCAGCCAGCTACGACCGCTGGTTCCGCGCCAG
GGTACAGGCCGCCCTGGATGATCCACGCCCGAGCATCCCTCACGACGAGGCGATGGCTCAGGTCGAACGGAGGCTAGAGG
ACAAGCGCAAGGCTCGCCGTGCTACCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1A9KKA1

Antitoxin

Source ID Structure
AlphaFold DB A0A1A9KKI2

References