Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 5270521..5271960 Replicon chromosome
Accession NZ_CP015878
Organism Pseudomonas citronellolis strain SJTE-3

Toxin (Protein)


Gene name - Uniprot ID A0A1A9KGK0
Locus tag A9C11_RS22825 Protein ID WP_064583923.1
Coordinates 5271391..5271960 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A1A5DB74
Locus tag A9C11_RS22820 Protein ID WP_058490851.1
Coordinates 5270521..5271381 (-) Length 287 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A9C11_RS22800 5265972..5266916 + 945 WP_064583921.1 bile acid:sodium symporter family protein -
A9C11_RS22805 5267059..5267373 + 315 WP_009620556.1 quaternary ammonium compound efflux SMR transporter SugE -
A9C11_RS22810 5267565..5267774 + 210 WP_009620558.1 cold-shock protein -
A9C11_RS22815 5267824..5269698 - 1875 WP_064583922.1 MFS transporter -
A9C11_RS22820 5270521..5271381 - 861 WP_058490851.1 AraC family transcriptional regulator Antitoxin
A9C11_RS22825 5271391..5271960 - 570 WP_064583923.1 GNAT family N-acetyltransferase Toxin
A9C11_RS22830 5272212..5275688 + 3477 WP_064583924.1 hybrid sensor histidine kinase/response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

DNA binding HTH domain, AraC-type

(197-274)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21078.40 Da        Isoelectric Point: 10.2120

>T63844 WP_064583923.1 NZ_CP015878:c5271960-5271391 [Pseudomonas citronellolis]
MFRPSPITLQRGALRLEPMVEADVPDLVALAEANREALKFMSAPQRPDWYRNSLAEQREGRALPLVVRLGNQLVGTTRFM
DFLPALPACEIGGTWLDAAQHGTGLNASIKYLMLRQAFDNWKMVRVQLKTAASNLRSQRAIEKLGAVREGVLRNHRRLAG
GRLDDTVLYSITDLEWPQVKAALEAGFIG

Download         Length: 570 bp

>T63844 NZ_CP015878:c5271960-5271391 [Pseudomonas citronellolis]
ATGTTCAGACCGTCACCCATCACCCTGCAGCGCGGTGCGCTGCGCCTGGAGCCCATGGTCGAGGCCGACGTGCCGGACCT
GGTGGCGCTGGCCGAGGCCAATCGCGAGGCGCTGAAGTTCATGAGCGCGCCGCAGCGCCCGGACTGGTACCGCAACAGCC
TCGCCGAGCAGCGCGAGGGCCGCGCCCTGCCGCTGGTGGTGCGCCTGGGCAACCAGCTGGTGGGCACCACCCGTTTCATG
GATTTCCTTCCGGCGCTGCCGGCCTGCGAGATCGGCGGCACCTGGCTGGATGCGGCGCAGCATGGCACCGGGCTGAACGC
CAGCATCAAGTACCTGATGCTGCGCCAGGCCTTCGACAACTGGAAGATGGTCCGCGTGCAGCTGAAGACCGCCGCCAGCA
ACCTGCGCTCGCAGCGCGCCATCGAGAAGCTCGGCGCGGTGCGCGAGGGCGTGCTGCGCAACCACCGGCGCCTGGCCGGC
GGGCGCCTGGACGACACCGTCCTCTACAGCATCACCGACCTGGAGTGGCCGCAGGTGAAGGCCGCCCTGGAAGCCGGCTT
CATCGGCTGA

Antitoxin


Download         Length: 287 a.a.        Molecular weight: 31636.99 Da        Isoelectric Point: 8.7317

>AT63844 WP_058490851.1 NZ_CP015878:c5271381-5270521 [Pseudomonas citronellolis]
MPLDSAHGERTRFWRAQELGGLELLHARFIEQRFAPHVHEGFALVLIEQGAQRFRHRGAEHLAPSGSLVLINPDEVHTGS
KAHEAGWLYRGFYPEIGQVGSVLDELELGGRGLPTFDASVLHDPELSRAFLHVHRLLESNASSLERQTCWREALLLLFQR
HARVPEARPAGQEPQAVARARELLAARLVEPPSLEELAAAVNLSPFHFARVFRKATGLPPHAWIKQRRLEQARALLKGGC
APASVAAQLGYADQSHLSRQFKQAYGVAPGEYRQACGRSGLPPGNL

Download         Length: 861 bp

>AT63844 NZ_CP015878:c5271381-5270521 [Pseudomonas citronellolis]
ATGCCCCTCGACAGCGCCCATGGCGAGCGCACGCGCTTCTGGCGGGCCCAGGAACTGGGCGGGCTGGAGTTGCTGCACGC
GCGCTTCATCGAGCAGCGCTTCGCCCCCCACGTCCACGAAGGCTTCGCCCTGGTGCTGATCGAGCAGGGCGCCCAGCGCT
TCCGCCACCGTGGCGCCGAGCACCTGGCGCCCAGCGGCAGCCTGGTGCTGATCAACCCCGACGAGGTCCACACCGGCTCC
AAGGCCCATGAGGCGGGCTGGCTGTACCGGGGGTTCTATCCGGAGATCGGGCAGGTCGGCAGCGTGCTCGACGAGCTGGA
GCTGGGTGGCCGCGGCCTGCCGACCTTCGACGCCAGCGTGTTGCACGATCCCGAGCTGAGCCGTGCCTTCCTGCACGTGC
ACCGCCTGCTGGAATCCAATGCCAGCAGCCTGGAGCGCCAGACCTGCTGGCGCGAGGCGTTGCTGTTGCTGTTCCAGCGC
CACGCGCGGGTGCCCGAGGCGCGCCCGGCCGGGCAGGAACCGCAAGCGGTGGCCCGCGCCCGCGAGCTGCTGGCGGCCCG
GCTGGTCGAGCCGCCGTCGCTGGAAGAGCTGGCGGCGGCGGTGAACCTGTCGCCCTTCCACTTCGCCCGGGTGTTCCGCA
AGGCCACCGGCCTGCCGCCCCACGCCTGGATCAAGCAACGCCGCCTGGAACAGGCCCGCGCCCTGCTCAAGGGCGGCTGC
GCGCCGGCCTCGGTGGCGGCGCAACTGGGCTACGCCGACCAGAGTCACCTGAGCCGCCAGTTCAAGCAGGCCTACGGCGT
GGCGCCGGGGGAATACCGCCAGGCTTGCGGACGCTCCGGCCTGCCACCCGGCAACCTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1A9KGK0

Antitoxin

Source ID Structure
AlphaFold DB A0A1A5DB74

References