Detailed information of TA system TA063842

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): slvAT/RES(toxin)
• Location: 4037909..4038801
• Replicon: chromosome
• Accession: NZ_CP015878
• Organism: Pseudomonas citronellolis strain SJTE-3

Toxin (Protein)

• Gene name: slvT
• Uniprot ID: A0A1A9KF17
• Locus tag: A9C11_RS17660
• Protein ID: WP_064583407.1
• Coordinates: 4037909..4038433 (-)
• Length: 175 a.a.

Antitoxin (Protein)

• Gene name: slvA
• Uniprot ID: A0A1A9KE41
• Locus tag: A9C11_RS17665
• Protein ID: WP_064583408.1
• Coordinates: 4038430..4038801 (-)
• Length: 124 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A9C11_RS17640	4034797..4035996	-	1200	WP_064583405.1	efflux RND transporter periplasmic adaptor subunit	-
A9C11_RS17645	4036262..4036660	+	399	Protein_3546	TIGR03746 family integrating conjugative element protein	-
A9C11_RS17650	4036657..4037546	+	890	Protein_3547	TIGR03749 family integrating conjugative element protein	-
A9C11_RS17655	4037536..4037892	+	357	WP_064583406.1	hypothetical protein	-
A9C11_RS17660	4037909..4038433	-	525	WP_064583407.1	RES family NAD+ phosphorylase	Toxin
A9C11_RS17665	4038430..4038801	-	372	WP_064583408.1	DUF2384 domain-containing protein	Antitoxin
A9C11_RS35340	4039084..4039536	-	453	WP_157763284.1	hypothetical protein	-
A9C11_RS17670	4039854..4040750	-	897	WP_064583409.1	transporter	-
A9C11_RS17675	4040845..4041951	-	1107	WP_064583410.1	hypothetical protein	-
A9C11_RS17680	4041972..4042985	-	1014	WP_009623331.1	4-hydroxy-2-oxovalerate aldolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (13-168)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (71-120)

Sequences

Toxin

Protein

• Length: 175 a.a.
• Molecular weight: 19162.54 Da
• Isoelectric Point: 4.4890

>T63842 WP_064583407.1 NZ_CP015878:c4038433-4037909 [Pseudomonas citronellolis]
MISRTLGEGGDATLYRVIVPAYAGTPLSGMGAARQGGRFNRPDQEALYLSLDEATALAEYKQDNPWLRPGTICTFFVNGL
RVADLSGGFDPEHWSPLWADFAVDWRAEWFDKSIEPPTWYMADDVVAVGLDGILFPSQARPGGTNLVVYNSSARPPAQLR
VYDPDGALQRLVQR

Nucleotide

• Length: 525 bp

>T63842 NZ_CP015878:c4038433-4037909 [Pseudomonas citronellolis]
ATGATTTCGAGGACGCTTGGCGAGGGCGGCGACGCCACCCTTTACCGTGTCATCGTGCCGGCTTACGCCGGCACGCCGCT
GTCGGGCATGGGCGCGGCGCGCCAAGGCGGCCGGTTCAATCGCCCCGATCAGGAAGCCTTGTATCTGTCGCTGGACGAGG
CGACGGCGCTGGCGGAGTACAAGCAGGATAATCCTTGGCTGCGTCCGGGCACGATCTGCACCTTCTTCGTTAACGGACTG
CGCGTGGCTGATCTGAGTGGCGGTTTCGACCCGGAGCATTGGTCGCCTCTTTGGGCCGACTTCGCGGTGGATTGGCGTGC
GGAGTGGTTCGATAAGTCCATTGAGCCGCCGACCTGGTACATGGCCGACGATGTGGTGGCGGTCGGGCTGGATGGCATTC
TCTTCCCCTCGCAGGCACGACCGGGCGGCACCAACCTGGTGGTCTACAACAGCTCGGCCAGGCCACCCGCCCAACTGCGG
GTCTACGACCCGGACGGTGCGCTGCAAAGGCTGGTACAGCGCTGA

Antitoxin

Protein

• Length: 124 a.a.
• Molecular weight: 13707.57 Da
• Isoelectric Point: 6.4726

>AT63842 WP_064583408.1 NZ_CP015878:c4038801-4038430 [Pseudomonas citronellolis]
MNTVLQEPFVERFREPNTPYLSPSKVGDFFGFRVQELAERAHVHRNTPTARPQAPQLQKYLQDMVRVLAVATEMTGDLDR
AAFLLRNEPLRTFGYKTADALIQEGRADAVIAYLESLAGGAAG

Nucleotide

• Length: 372 bp

>AT63842 NZ_CP015878:c4038801-4038430 [Pseudomonas citronellolis]
ATGAATACCGTGCTGCAAGAACCCTTCGTCGAGCGGTTCCGCGAGCCCAATACACCGTACCTGTCGCCTTCCAAGGTGGG
AGATTTCTTCGGTTTCCGGGTGCAGGAGCTAGCCGAGCGTGCGCATGTGCATCGCAATACCCCGACGGCACGACCCCAGG
CACCGCAGTTGCAGAAGTACCTGCAGGATATGGTGCGAGTGCTGGCGGTGGCCACCGAGATGACCGGCGACCTCGACCGT
GCTGCCTTCCTGCTGCGCAATGAGCCGCTGCGGACCTTCGGCTACAAAACCGCCGATGCGCTGATCCAGGAAGGGCGGGC
CGATGCGGTCATTGCCTATCTGGAGTCCCTGGCCGGCGGCGCTGCCGGATGA

Structures

Toxin

• AlphaFold DB: A0A1A9KF17

Antitoxin

• AlphaFold DB: A0A1A9KE41