Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE(toxin)
Location 1025112..1025661 Replicon chromosome
Accession NZ_CP015878
Organism Pseudomonas citronellolis strain SJTE-3

Toxin (Protein)


Gene name relE Uniprot ID A0A1A9K6A2
Locus tag A9C11_RS04550 Protein ID WP_064581900.1
Coordinates 1025350..1025661 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1A9K6S2
Locus tag A9C11_RS04545 Protein ID WP_064581899.1
Coordinates 1025112..1025360 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A9C11_RS04510 1021261..1021905 + 645 WP_009617419.1 carbonate dehydratase -
A9C11_RS04515 1021993..1022988 + 996 WP_064581894.1 isocitrate/isopropylmalate dehydrogenase family protein -
A9C11_RS04520 1022991..1023185 - 195 WP_009617424.1 hypothetical protein -
A9C11_RS04525 1023524..1023769 + 246 WP_064581895.1 hypothetical protein -
A9C11_RS04530 1023858..1024112 + 255 WP_064581896.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
A9C11_RS04535 1024109..1024360 + 252 WP_064581897.1 HigA family addiction module antidote protein -
A9C11_RS04545 1025112..1025360 + 249 WP_064581899.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
A9C11_RS04550 1025350..1025661 + 312 WP_064581900.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A9C11_RS04555 1025966..1026946 - 981 WP_014819624.1 IS5-like element ISAch1 family transposase -
A9C11_RS33890 1027162..1027827 + 666 Protein_912 hypothetical protein -
A9C11_RS35195 1027769..1028692 - 924 WP_157763219.1 hypothetical protein -
A9C11_RS04570 1029040..1030140 - 1101 WP_058071540.1 redox-regulated ATPase YchF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1025966..1026946 980


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-92)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11818.83 Da        Isoelectric Point: 10.4336

>T63837 WP_064581900.1 NZ_CP015878:1025350-1025661 [Pseudomonas citronellolis]
MNSESAGGQATYTLRIKESAEKEWRKLPDQIRATFKKKLAERLLNPRVEKDKLSGMKDCYKIKLKDAGYRLVYRVDDGVL
VIEIIAAGKRERGEAYMAAKKRL

Download         Length: 312 bp

>T63837 NZ_CP015878:1025350-1025661 [Pseudomonas citronellolis]
ATGAACTCTGAATCAGCCGGTGGGCAAGCGACGTACACACTGAGGATCAAGGAGAGCGCGGAGAAGGAGTGGCGGAAGTT
GCCAGACCAGATTCGCGCAACCTTCAAGAAAAAGCTGGCAGAGCGCCTACTCAACCCGCGAGTTGAGAAAGACAAGCTCT
CAGGCATGAAGGACTGCTACAAGATCAAGCTCAAGGATGCCGGTTACCGGCTGGTTTACCGAGTCGACGATGGCGTGTTG
GTGATCGAGATAATCGCCGCCGGGAAACGAGAGCGTGGTGAGGCTTACATGGCGGCGAAGAAGCGCCTCTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8945.24 Da        Isoelectric Point: 4.4341

>AT63837 WP_064581899.1 NZ_CP015878:1025112-1025360 [Pseudomonas citronellolis]
MAHAVLADVAASITELKKDPMGTIEAGHGKPVVILNRNAPAFYAVPPDVYEQMLEALDDAFLARLVRERSGEPSREITLD
EL

Download         Length: 249 bp

>AT63837 NZ_CP015878:1025112-1025360 [Pseudomonas citronellolis]
ATGGCACACGCCGTTTTAGCGGACGTAGCAGCCTCCATCACCGAGCTGAAGAAGGATCCCATGGGGACCATCGAGGCCGG
GCACGGTAAACCCGTTGTGATTCTGAACCGCAATGCACCCGCCTTTTACGCGGTGCCGCCAGATGTGTACGAACAGATGC
TTGAGGCGCTGGATGATGCATTCCTGGCTCGACTGGTGAGGGAGCGCAGCGGAGAACCATCGCGGGAAATTACGTTGGAT
GAACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1A9K6A2

Antitoxin

Source ID Structure
AlphaFold DB A0A1A9K6S2

References