Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 125589..126094 Replicon chromosome
Accession NZ_CP015878
Organism Pseudomonas citronellolis strain SJTE-3

Toxin (Protein)


Gene name parE Uniprot ID W5IQ81
Locus tag A9C11_RS00565 Protein ID WP_009614629.1
Coordinates 125589..125870 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID W5IQE2
Locus tag A9C11_RS00570 Protein ID WP_009614631.1
Coordinates 125867..126094 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A9C11_RS00535 120952..122154 + 1203 WP_043312509.1 zinc metallochaperone GTPase ZigA -
A9C11_RS00540 122154..122771 + 618 WP_064581557.1 DUF1826 domain-containing protein -
A9C11_RS00545 122768..123223 - 456 WP_064584953.1 GNAT family N-acetyltransferase -
A9C11_RS00550 123282..124199 - 918 WP_064581558.1 LysR family transcriptional regulator -
A9C11_RS00555 124297..124578 + 282 WP_064581559.1 DUF2218 domain-containing protein -
A9C11_RS00560 124619..125329 - 711 WP_064581560.1 RcnB family protein -
A9C11_RS00565 125589..125870 - 282 WP_009614629.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A9C11_RS00570 125867..126094 - 228 WP_009614631.1 CopG family ribbon-helix-helix protein Antitoxin
A9C11_RS00575 126374..127330 + 957 WP_064581561.1 agmatinase -
A9C11_RS00580 127405..128331 + 927 WP_064581562.1 LysR family transcriptional regulator -
A9C11_RS00585 128328..129059 + 732 WP_064581563.1 phytanoyl-CoA dioxygenase family protein -
A9C11_RS00590 129071..129472 + 402 WP_064581564.1 GFA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10251.74 Da        Isoelectric Point: 6.4614

>T63834 WP_009614629.1 NZ_CP015878:c125870-125589 [Pseudomonas citronellolis]
MSLQWTHKAAADLDGLYDHYVVLIGPEKALKAIQDVVGQVKALADLSLSSVGRPSEVPGVRELPLERWPYQAAYRVKGRD
VQILRIDSVDNPG

Download         Length: 282 bp

>T63834 NZ_CP015878:c125870-125589 [Pseudomonas citronellolis]
ATGAGCCTGCAGTGGACGCACAAGGCGGCGGCCGACCTGGACGGCCTGTACGACCACTACGTGGTGCTGATCGGCCCGGA
GAAGGCGCTGAAGGCTATCCAGGACGTGGTCGGCCAGGTGAAGGCGCTGGCCGACCTCAGCCTGAGCAGCGTCGGCCGGC
CCAGCGAGGTGCCCGGCGTGCGCGAATTGCCGCTGGAACGCTGGCCCTACCAGGCCGCCTACCGGGTAAAAGGCCGCGAT
GTACAAATTTTGCGCATCGATTCTGTGGATAACCCGGGGTAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8357.42 Da        Isoelectric Point: 6.6405

>AT63834 WP_009614631.1 NZ_CP015878:c126094-125867 [Pseudomonas citronellolis]
MTTVISFRADDALAKALDQLARATHRDRPYHLRQALAQYLERQSWHVAAIDEGLADANAGHLLPHAEIEAKWGLA

Download         Length: 228 bp

>AT63834 NZ_CP015878:c126094-125867 [Pseudomonas citronellolis]
TTGACCACCGTAATCTCCTTCCGCGCCGATGACGCCCTGGCCAAGGCCCTGGACCAACTGGCCCGAGCCACCCACCGGGA
CCGCCCCTACCACCTGCGCCAGGCCCTGGCGCAGTACCTGGAGCGCCAGAGCTGGCACGTGGCGGCCATCGACGAGGGCC
TGGCCGACGCCAACGCCGGGCACCTGCTGCCGCACGCCGAGATAGAAGCCAAGTGGGGGCTGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1A5D1B8

Antitoxin

Source ID Structure
AlphaFold DB A0A1S1GJG7

References