Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
| Location | 5727852..5729581 | Replicon | chromosome |
| Accession | NZ_CP015876 | ||
| Organism | Pseudomonas putida SJTE-1 | ||
Toxin (Protein)
| Gene name | pmenT | Uniprot ID | I3UUH3 |
| Locus tag | A210_RS25695 | Protein ID | WP_014754748.1 |
| Coordinates | 5728940..5729581 (-) | Length | 214 a.a. |
Antitoxin (Protein)
| Gene name | pmenA | Uniprot ID | I3UUH2 |
| Locus tag | A210_RS25690 | Protein ID | WP_014754747.1 |
| Coordinates | 5727852..5728940 (-) | Length | 363 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A210_RS25675 | 5723482..5724300 | - | 819 | WP_173881454.1 | HDOD domain-containing protein | - |
| A210_RS25680 | 5724476..5725672 | + | 1197 | WP_004575470.1 | class I SAM-dependent rRNA methyltransferase | - |
| A210_RS25685 | 5725943..5727784 | + | 1842 | WP_003249056.1 | dihydroxy-acid dehydratase | - |
| A210_RS25690 | 5727852..5728940 | - | 1089 | WP_014754747.1 | macro domain-containing protein | Antitoxin |
| A210_RS25695 | 5728940..5729581 | - | 642 | WP_014754748.1 | DUF4433 domain-containing protein | Toxin |
| A210_RS25700 | 5729578..5730156 | - | 579 | WP_019752696.1 | DUF4433 domain-containing protein | - |
| A210_RS25705 | 5730254..5731309 | - | 1056 | WP_014754750.1 | phosphorylcholine phosphatase | - |
| A210_RS25710 | 5731554..5732945 | + | 1392 | WP_003249050.1 | L-cystine transporter | - |
| A210_RS25715 | 5733364..5733879 | - | 516 | WP_003249048.1 | dihydrofolate reductase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | motB / motA / waaA / pilJ / pilH / pilG / pilQ | 5424259..5744770 | 320511 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 214 a.a. Molecular weight: 24590.18 Da Isoelectric Point: 9.5438
>T63827 WP_014754748.1 NZ_CP015876:c5729581-5728940 [Pseudomonas putida SJTE-1]
MIYSSLNPSKALIWRIVHRDNLSWVLDHGLHAVSSGKLSSTYVGIGNPELISKRAQRRVPLEPNGTLADYVPFYFTPFSV
MMKNIHSGWGVPQRRNEEIVILVSSLYHAQSLGLQFVFTDAHAYPHWAGYYSNLTQLDKIDWEILQRRDFKRDPDDPRKM
ERYQAEALIHGHVPVAALLGIVCYNEALKGRVDKEVQQRRLNLPVYARPGWYF
MIYSSLNPSKALIWRIVHRDNLSWVLDHGLHAVSSGKLSSTYVGIGNPELISKRAQRRVPLEPNGTLADYVPFYFTPFSV
MMKNIHSGWGVPQRRNEEIVILVSSLYHAQSLGLQFVFTDAHAYPHWAGYYSNLTQLDKIDWEILQRRDFKRDPDDPRKM
ERYQAEALIHGHVPVAALLGIVCYNEALKGRVDKEVQQRRLNLPVYARPGWYF
Download Length: 642 bp
>T63827 NZ_CP015876:c5729581-5728940 [Pseudomonas putida SJTE-1]
ATGATTTATTCCAGTCTCAACCCATCCAAGGCACTCATCTGGCGAATTGTTCACCGCGATAACCTGTCGTGGGTTCTGGA
TCATGGGCTGCACGCTGTCTCCTCCGGGAAGCTTTCCAGCACCTATGTTGGAATTGGCAATCCAGAGCTGATCAGCAAGC
GAGCGCAACGCCGTGTGCCTCTGGAACCCAATGGGACGCTGGCGGATTATGTACCGTTCTATTTCACCCCGTTCTCCGTG
ATGATGAAGAATATTCATTCGGGGTGGGGTGTTCCTCAGCGGCGGAACGAAGAGATCGTGATTCTTGTCTCCAGCCTGTA
CCATGCGCAGTCGCTGGGTTTGCAGTTTGTGTTCACGGATGCCCATGCCTACCCGCATTGGGCCGGCTACTACAGTAACC
TCACGCAGCTGGACAAAATCGATTGGGAGATTTTGCAGCGCAGGGATTTCAAACGTGACCCTGATGACCCTCGGAAAATG
GAGCGTTATCAGGCGGAGGCCCTTATCCATGGACATGTCCCAGTTGCTGCCCTTCTGGGAATTGTCTGCTACAACGAAGC
TTTGAAGGGGCGTGTCGACAAGGAGGTTCAGCAACGTCGATTGAATCTCCCTGTGTATGCTCGTCCTGGGTGGTACTTCT
AA
ATGATTTATTCCAGTCTCAACCCATCCAAGGCACTCATCTGGCGAATTGTTCACCGCGATAACCTGTCGTGGGTTCTGGA
TCATGGGCTGCACGCTGTCTCCTCCGGGAAGCTTTCCAGCACCTATGTTGGAATTGGCAATCCAGAGCTGATCAGCAAGC
GAGCGCAACGCCGTGTGCCTCTGGAACCCAATGGGACGCTGGCGGATTATGTACCGTTCTATTTCACCCCGTTCTCCGTG
ATGATGAAGAATATTCATTCGGGGTGGGGTGTTCCTCAGCGGCGGAACGAAGAGATCGTGATTCTTGTCTCCAGCCTGTA
CCATGCGCAGTCGCTGGGTTTGCAGTTTGTGTTCACGGATGCCCATGCCTACCCGCATTGGGCCGGCTACTACAGTAACC
TCACGCAGCTGGACAAAATCGATTGGGAGATTTTGCAGCGCAGGGATTTCAAACGTGACCCTGATGACCCTCGGAAAATG
GAGCGTTATCAGGCGGAGGCCCTTATCCATGGACATGTCCCAGTTGCTGCCCTTCTGGGAATTGTCTGCTACAACGAAGC
TTTGAAGGGGCGTGTCGACAAGGAGGTTCAGCAACGTCGATTGAATCTCCCTGTGTATGCTCGTCCTGGGTGGTACTTCT
AA
Antitoxin
Download Length: 363 a.a. Molecular weight: 40625.75 Da Isoelectric Point: 6.5916
>AT63827 WP_014754747.1 NZ_CP015876:c5728940-5727852 [Pseudomonas putida SJTE-1]
MIHFMQGNLLEAKAEALVNTVNTVGVMGKGIALMFKERFVENYRQYAAACKAKEVVTGKMFVTEVRELDGPRWIVNFPTK
RHWRSPSQIGWIVEGLHDLRNFIINNQVASIAIPPLGAGNGGLSWAAVREQIQRVLGDLDADVFVFEPTANYQNVSKRSG
VEVLTPARALIAELVRRYWVLGMECSLLEVQKLAWFLERSIERFTPGINPLELKFVAHKYGPYANRLEHLLDNLDGSYLH
CRKRISDAGPLDVIWFDEGRKSFLQAYLNSEAKAYLPALEFTAELIDGFESPFGMELLATVDWLLHEDGVEPTVPAVREH
LKNWSGGVGAAARKSKLFDDEALGIALQKLSMFRSDPATSLH
MIHFMQGNLLEAKAEALVNTVNTVGVMGKGIALMFKERFVENYRQYAAACKAKEVVTGKMFVTEVRELDGPRWIVNFPTK
RHWRSPSQIGWIVEGLHDLRNFIINNQVASIAIPPLGAGNGGLSWAAVREQIQRVLGDLDADVFVFEPTANYQNVSKRSG
VEVLTPARALIAELVRRYWVLGMECSLLEVQKLAWFLERSIERFTPGINPLELKFVAHKYGPYANRLEHLLDNLDGSYLH
CRKRISDAGPLDVIWFDEGRKSFLQAYLNSEAKAYLPALEFTAELIDGFESPFGMELLATVDWLLHEDGVEPTVPAVREH
LKNWSGGVGAAARKSKLFDDEALGIALQKLSMFRSDPATSLH
Download Length: 1089 bp
>AT63827 NZ_CP015876:c5728940-5727852 [Pseudomonas putida SJTE-1]
ATGATCCACTTTATGCAAGGTAACCTGCTGGAGGCCAAGGCCGAAGCGCTGGTTAACACAGTTAACACCGTAGGGGTGAT
GGGGAAAGGCATCGCGCTGATGTTCAAGGAGCGTTTTGTCGAGAACTATCGCCAGTATGCTGCTGCCTGCAAAGCGAAAG
AGGTAGTTACCGGGAAGATGTTTGTTACTGAAGTGCGTGAGCTGGACGGTCCACGCTGGATTGTGAATTTTCCAACCAAG
CGGCATTGGCGCTCACCTTCGCAAATCGGCTGGATCGTCGAGGGCCTTCATGATTTGCGCAACTTCATTATCAATAACCA
GGTGGCATCGATTGCTATCCCTCCACTTGGTGCTGGTAATGGAGGGTTGTCTTGGGCTGCGGTACGAGAACAGATTCAGA
GGGTTCTGGGTGATCTGGACGCGGATGTTTTCGTTTTCGAGCCTACGGCAAATTATCAAAACGTTTCCAAGCGCAGTGGT
GTTGAGGTTTTGACCCCGGCTCGAGCCTTGATTGCAGAGCTTGTGCGCCGCTATTGGGTGCTGGGGATGGAGTGCAGCTT
GCTCGAAGTCCAGAAGCTTGCCTGGTTTCTGGAGCGATCAATCGAGCGGTTCACGCCAGGCATCAACCCATTGGAATTGA
AGTTTGTCGCTCATAAGTATGGTCCTTACGCCAACCGGCTTGAGCACCTGCTAGATAACCTGGATGGCAGCTATTTACAC
TGCCGAAAGCGGATCAGCGATGCAGGCCCTCTGGACGTTATCTGGTTTGATGAGGGGCGCAAGTCATTTTTACAGGCGTA
TCTGAACAGTGAAGCCAAGGCCTATTTGCCGGCGTTGGAGTTCACTGCCGAGTTGATTGATGGTTTCGAGTCTCCGTTTG
GTATGGAGCTGCTGGCCACCGTTGATTGGTTATTGCATGAAGATGGTGTTGAGCCGACAGTCCCTGCAGTTCGCGAACAC
CTGAAAAATTGGTCAGGAGGGGTAGGTGCCGCTGCTCGAAAAAGCAAACTGTTCGATGACGAGGCACTTGGAATCGCTCT
TCAAAAGCTGTCAATGTTTCGATCCGACCCAGCCACCTCGCTTCACTGA
ATGATCCACTTTATGCAAGGTAACCTGCTGGAGGCCAAGGCCGAAGCGCTGGTTAACACAGTTAACACCGTAGGGGTGAT
GGGGAAAGGCATCGCGCTGATGTTCAAGGAGCGTTTTGTCGAGAACTATCGCCAGTATGCTGCTGCCTGCAAAGCGAAAG
AGGTAGTTACCGGGAAGATGTTTGTTACTGAAGTGCGTGAGCTGGACGGTCCACGCTGGATTGTGAATTTTCCAACCAAG
CGGCATTGGCGCTCACCTTCGCAAATCGGCTGGATCGTCGAGGGCCTTCATGATTTGCGCAACTTCATTATCAATAACCA
GGTGGCATCGATTGCTATCCCTCCACTTGGTGCTGGTAATGGAGGGTTGTCTTGGGCTGCGGTACGAGAACAGATTCAGA
GGGTTCTGGGTGATCTGGACGCGGATGTTTTCGTTTTCGAGCCTACGGCAAATTATCAAAACGTTTCCAAGCGCAGTGGT
GTTGAGGTTTTGACCCCGGCTCGAGCCTTGATTGCAGAGCTTGTGCGCCGCTATTGGGTGCTGGGGATGGAGTGCAGCTT
GCTCGAAGTCCAGAAGCTTGCCTGGTTTCTGGAGCGATCAATCGAGCGGTTCACGCCAGGCATCAACCCATTGGAATTGA
AGTTTGTCGCTCATAAGTATGGTCCTTACGCCAACCGGCTTGAGCACCTGCTAGATAACCTGGATGGCAGCTATTTACAC
TGCCGAAAGCGGATCAGCGATGCAGGCCCTCTGGACGTTATCTGGTTTGATGAGGGGCGCAAGTCATTTTTACAGGCGTA
TCTGAACAGTGAAGCCAAGGCCTATTTGCCGGCGTTGGAGTTCACTGCCGAGTTGATTGATGGTTTCGAGTCTCCGTTTG
GTATGGAGCTGCTGGCCACCGTTGATTGGTTATTGCATGAAGATGGTGTTGAGCCGACAGTCCCTGCAGTTCGCGAACAC
CTGAAAAATTGGTCAGGAGGGGTAGGTGCCGCTGCTCGAAAAAGCAAACTGTTCGATGACGAGGCACTTGGAATCGCTCT
TCAAAAGCTGTCAATGTTTCGATCCGACCCAGCCACCTCGCTTCACTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|