Detailed information of TA system TA063781

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 3672417..3672897
• Replicon: chromosome
• Accession: NZ_CP015852
• Organism: Pseudomonas koreensis strain CRS05-R5

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: A8L59_RS27165
• Protein ID: WP_082920330.1
• Coordinates: 3672613..3672897 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A2K4IEG4
• Locus tag: A8L59_RS16010
• Protein ID: WP_064588150.1
• Coordinates: 3672417..3672623 (+)
• Length: 69 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A8L59_RS15995	3667896..3670130	+	2235	WP_064588147.1	cadherin-like domain-containing protein	-
A8L59_RS16000	3670203..3670667	+	465	WP_064588148.1	curlin	-
A8L59_RS16005	3670696..3672147	+	1452	WP_064588149.1	curlin	-
A8L59_RS16010	3672417..3672623	+	207	WP_064588150.1	hypothetical protein	Antitoxin
A8L59_RS27165	3672613..3672897	+	285	WP_082920330.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
A8L59_RS16015	3672972..3673190	-	219	WP_034152590.1	hypothetical protein	-
A8L59_RS16020	3673400..3673768	-	369	Protein_3185	hypothetical protein	-
A8L59_RS16025	3674851..3675711	-	861	WP_064588151.1	curli production assembly/transport protein CsgG	-
A8L59_RS16030	3675741..3676172	-	432	WP_016987875.1	curli production assembly protein CsgF	-
A8L59_RS16035	3676169..3676561	-	393	WP_064588152.1	curli production assembly/transport protein CsgE	-
A8L59_RS16040	3676558..3677097	-	540	WP_064588153.1	type II secretion system protein	-
A8L59_RS16045	3677072..3677446	-	375	WP_064588154.1	type II secretion system GspH family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10865.66 Da
• Isoelectric Point: 10.7384

>T63781 WP_082920330.1 NZ_CP015852:3672613-3672897 [Pseudomonas koreensis]
MQIKWRPKARVELSKILKYIGERNFIAATALHKSVVKTTSALCWHPHLYRNGRSPGTREIVVSPNYLVVYQVANQIEIVS
ILHARQEYPRRDPG

Nucleotide

• Length: 285 bp

>T63781 NZ_CP015852:3672613-3672897 [Pseudomonas koreensis]
ATGCAGATTAAGTGGCGACCCAAGGCCCGGGTCGAACTCTCGAAAATCCTTAAGTACATTGGCGAGCGAAATTTTATAGC
GGCGACTGCACTTCACAAGTCCGTCGTCAAAACTACATCTGCGCTTTGTTGGCATCCACACCTGTATCGCAACGGCCGCT
CTCCCGGCACTCGAGAGATTGTGGTAAGCCCGAACTATCTCGTCGTTTATCAAGTGGCGAACCAAATTGAGATTGTGAGC
ATCTTGCATGCGCGTCAGGAGTACCCTCGACGCGACCCCGGTTAA

Antitoxin

Protein

• Length: 69 a.a.
• Molecular weight: 7691.56 Da
• Isoelectric Point: 3.7610

>AT63781 WP_064588150.1 NZ_CP015852:3672417-3672623 [Pseudomonas koreensis]
MIDPSLIDPLCPVVSDLDPEEQAASYDRWFRAEVQASLDDPRPSIPHEQVMEEMDALMESMRKSADAD

Nucleotide

• Length: 207 bp

>AT63781 NZ_CP015852:3672417-3672623 [Pseudomonas koreensis]
ATGATCGACCCGTCCTTGATCGACCCACTGTGCCCGGTTGTTTCGGATCTTGATCCCGAGGAGCAGGCTGCGAGTTATGA
CCGTTGGTTTCGGGCCGAAGTACAGGCCTCTCTCGATGATCCGCGTCCGAGTATTCCCCATGAGCAAGTGATGGAGGAAA
TGGATGCCTTGATGGAATCAATGCGCAAAAGCGCTGATGCAGATTAA

Structures

Antitoxin

• AlphaFold DB: A0A2K4IEG4