63780

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2681776..2683000 Replicon chromosome
Accession NZ_CP015852
Organism Pseudomonas koreensis strain CRS05-R5

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag A8L59_RS11690 Protein ID WP_064587317.1
Coordinates 2681776..2682366 (-) Length 197 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag A8L59_RS11695 Protein ID WP_064587318.1
Coordinates 2682443..2683000 (-) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A8L59_RS11665 2677553..2678326 + 774 WP_064587312.1 AraC family transcriptional regulator -
A8L59_RS11670 2678337..2679104 - 768 WP_064587313.1 phosphonate ABC transporter, permease protein PhnE -
A8L59_RS11675 2679101..2679928 - 828 WP_064587314.1 ABC transporter permease subunit -
A8L59_RS11680 2679922..2680719 - 798 WP_064587315.1 ATP-binding cassette domain-containing protein -
A8L59_RS11685 2680716..2681585 - 870 WP_064587316.1 putative selenate ABC transporter substrate-binding protein -
A8L59_RS11690 2681776..2682366 - 591 WP_064587317.1 HD domain-containing protein Toxin
A8L59_RS11695 2682443..2683000 - 558 WP_064587318.1 helix-turn-helix domain-containing protein Antitoxin
A8L59_RS11700 2683075..2683473 - 399 WP_064587319.1 RidA family protein -
A8L59_RS11705 2683596..2684522 + 927 WP_064587320.1 LysR family transcriptional regulator -
A8L59_RS11710 2684500..2685360 - 861 WP_064587321.1 LysR family transcriptional regulator -
A8L59_RS11715 2685472..2686524 + 1053 WP_064587322.1 agmatine deiminase family protein -
A8L59_RS11720 2686528..2687436 + 909 WP_064587323.1 N-carbamoylputrescine amidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-167)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-63)


Sequences

Toxin        


Download         Length: 197 a.a.        Molecular weight: 22059.85 Da        Isoelectric Point: 4.8466

>T63780 WP_064587317.1 NZ_CP015852:c2682366-2681776 [Pseudomonas koreensis]
MDIDTIKRRLEFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAMVFADQLTGLDVLKVLKMCVVHDLGEAINGDIP
AVNQAAFPDKGEQERNDLLLLTRSLDETLRSEILALWDDYENAQSAEAKAVKALDKLETLLQHNQGLNPADFDYAFNLGY
GKQYTSADPVFATLRALIDQDTRQRIGDAQRGHERS

Download         Length: 591 bp

>T63780 NZ_CP015852:c2682366-2681776 [Pseudomonas koreensis]
ATGGATATCGACACGATCAAGCGACGCCTCGAATTCCTGCGCGAAGCGGAAAAACTCAAAGACGTCCTGCGCAGCGCCCA
CACCTCCAGCGGCCGCACCGAAAGCACTGCCGAACACAGTTGGCGCCTGTGCCTGATGGCGATGGTCTTCGCCGATCAAC
TGACGGGCCTCGACGTGCTGAAAGTCCTGAAGATGTGCGTGGTCCACGATCTGGGCGAAGCCATCAATGGCGACATTCCC
GCGGTCAATCAGGCCGCTTTCCCCGACAAGGGCGAGCAGGAACGTAACGACCTTCTGTTACTGACCCGTTCGCTCGACGA
GACGCTGCGCAGCGAGATTCTGGCGCTGTGGGACGATTATGAAAACGCACAGTCGGCCGAGGCCAAAGCGGTCAAGGCGC
TGGATAAGCTGGAAACCTTGTTGCAACACAATCAAGGTTTGAACCCGGCGGATTTCGATTACGCTTTCAATCTCGGCTAC
GGCAAGCAGTACACCAGCGCCGACCCGGTCTTCGCCACCCTGCGGGCACTGATCGATCAAGACACGCGACAGCGCATCGG
CGACGCTCAACGCGGCCACGAGCGATCCTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20606.70 Da        Isoelectric Point: 9.4776

>AT63780 WP_064587318.1 NZ_CP015852:c2683000-2682443 [Pseudomonas koreensis]
MSDPILKPVLPGIALRRWRLLHRVKQTHAAQLFNVTQSTISRWESGVQAMEPAAQQQLERLLGARLNSAADQALARLVNE
SQRPMHLICDVSHRLLACSPARAAEFSRPLSELLGQSLWRYATAEILLRESALASSGWHEIQAPAAVEFVTGRNDSEIVP
IRQSLCRWTRIALSDGTATRLVETL

Download         Length: 558 bp

>AT63780 NZ_CP015852:c2683000-2682443 [Pseudomonas koreensis]
ATGTCCGATCCGATATTGAAACCCGTCTTGCCCGGCATCGCCCTGCGCCGCTGGCGCCTGCTGCATCGCGTCAAACAGAC
ACACGCGGCGCAGTTGTTCAATGTCACCCAATCGACTATCTCCCGCTGGGAAAGCGGCGTTCAGGCCATGGAGCCCGCCG
CGCAGCAACAGCTGGAGCGTCTGCTCGGCGCACGCCTGAACAGCGCGGCCGATCAGGCGCTGGCCCGGCTGGTCAATGAA
AGTCAGCGCCCGATGCACCTGATCTGTGATGTTTCCCATCGCTTGCTGGCGTGCTCTCCGGCCCGCGCCGCCGAGTTCAG
CCGTCCGCTCAGCGAGCTGTTGGGGCAGTCGCTCTGGCGCTACGCAACCGCTGAAATACTGCTCAGGGAGTCGGCCCTGG
CGAGCAGCGGCTGGCACGAGATTCAGGCGCCCGCAGCGGTGGAGTTCGTCACCGGCCGCAACGATTCCGAGATCGTGCCA
ATCCGTCAAAGCCTGTGCCGCTGGACGCGCATCGCACTGTCCGATGGCACCGCCACACGCCTGGTCGAAACGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References