Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 331530..332059 Replicon plasmid unnamed
Accession NZ_CP015851
Organism Ralstonia solanacearum strain YC40-M

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A3768_RS18730 Protein ID WP_016722340.1
Coordinates 331530..331757 (+) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag A3768_RS18735 Protein ID WP_016722339.1
Coordinates 331754..332059 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A3768_RS18710 327767..328366 - 600 WP_016722344.1 GNAT family N-acetyltransferase -
A3768_RS18715 328499..329050 + 552 WP_011003399.1 helix-turn-helix transcriptional regulator -
A3768_RS18720 329228..330049 + 822 WP_011003398.1 GntR family transcriptional regulator -
A3768_RS18725 330176..331375 + 1200 WP_016726513.1 MFS transporter -
A3768_RS18730 331530..331757 + 228 WP_016722340.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A3768_RS18735 331754..332059 + 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
A3768_RS18740 332272..333585 + 1314 WP_043897984.1 metabolite/H+ symporter -
A3768_RS18745 333755..334042 + 288 WP_043898169.1 barstar family protein -
A3768_RS18750 334376..334684 - 309 WP_043897983.1 hypothetical protein -
A3768_RS26575 335181..335405 - 225 WP_144061921.1 hypothetical protein -
A3768_RS26580 335729..335880 - 152 Protein_238 IS5/IS1182 family transposase -
A3768_RS26585 335887..336036 - 150 WP_155738951.1 hypothetical protein -
A3768_RS18755 336033..336998 - 966 WP_016721735.1 IS5 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cyaB / motA / cheW / cheB / cheY / adeG / fliI / fliG / fliM / flgG / flgC 1..1907366 1907366
- flank IS/Tn - - 336033..336998 965


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-67)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8566.85 Da        Isoelectric Point: 7.2789

>T63776 WP_016722340.1 NZ_CP015851:331530-331757 [Ralstonia solanacearum]
VRIDRLQMGHPGNMKAVRDGIRELRIDHGPGDRLYFVRHGVVLIVLLCGGDKSTQETDIRRAIDLSRRLDVDDME

Download         Length: 228 bp

>T63776 NZ_CP015851:331530-331757 [Ralstonia solanacearum]
GTGCGCATCGACCGCCTGCAGATGGGCCACCCAGGCAACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCGA
TCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCGA
CGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT63776 WP_016722339.1 NZ_CP015851:331754-332059 [Ralstonia solanacearum]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT63776 NZ_CP015851:331754-332059 [Ralstonia solanacearum]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGCGAGGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References