Detailed information of TA system
Overview
TA module
| Type | III | Classification (family/domain) | tenpIN/- |
| Location | 5645829..5646368 | Replicon | chromosome |
| Accession | NC_005126 | ||
| Organism | Photorhabdus luminescens subsp. laumondii TTO1 | ||
Toxin (Protein)
| Gene name | tenpN | Uniprot ID | Q7MY23 |
| Locus tag | PLU_RS24160 | Protein ID | WP_011148929.1 |
| Coordinates | 5645829..5646260 (-) | Length | 144 a.a. |
Antitoxin (RNA)
| Gene name | tenpI | ||
| Locus tag | - | ||
| Coordinates | 5646319..5646368 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PLU_RS24135 (plu4867) | 5641325..5641783 | + | 459 | WP_011148924.1 | dUTP diphosphatase | - |
| PLU_RS24140 (plu4868) | 5642024..5642623 | + | 600 | WP_011148925.1 | nucleoid occlusion factor SlmA | - |
| PLU_RS24145 (plu4869) | 5642683..5643324 | - | 642 | WP_011148926.1 | orotate phosphoribosyltransferase | - |
| PLU_RS24150 (plu4870) | 5643409..5644137 | - | 729 | WP_011148927.1 | ribonuclease PH | - |
| PLU_RS24155 (plu4871) | 5644264..5645127 | + | 864 | WP_011148928.1 | YicC family protein | - |
| PLU_RS24160 (plu4873) | 5645829..5646260 | - | 432 | WP_011148929.1 | hypothetical protein | Toxin |
| - | 5646319..5646368 | - | 50 | - | - | Antitoxin |
| PLU_RS24165 (plu4874) | 5646488..5646682 | - | 195 | WP_011148930.1 | hypothetical protein | - |
| PLU_RS24170 (plu4876) | 5647318..5648352 | + | 1035 | WP_071824185.1 | reverse transcriptase family protein | - |
| PLU_RS24175 (plu4877) | 5648342..5649003 | + | 662 | Protein_4813 | retron Ec48 family effector membrane protein | - |
| PLU_RS24180 (plu4879) | 5649581..5650531 | - | 951 | WP_011148935.1 | hypothetical protein | - |
| PLU_RS25865 | 5650808..5650891 | + | 84 | WP_071824186.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 144 a.a. Molecular weight: 16736.27 Da Isoelectric Point: 8.2240
>T6371 WP_011148929.1 NC_005126:c5646260-5645829 [Photorhabdus laumondii subsp. laumondii TTO1]
MILRQIKQDVYNRLCENRPQVLEKNRGYGVISITLNGLTFAVPLRSNLNHPNGFKTIFIKEKKCWSGLDYSKALLIDVDD
LEPQAFKLKMEKEYEKLKANEKKIEVEFGAYVQGYIEYINTGEGDDRCYKFTTLQYFHRDLGL
MILRQIKQDVYNRLCENRPQVLEKNRGYGVISITLNGLTFAVPLRSNLNHPNGFKTIFIKEKKCWSGLDYSKALLIDVDD
LEPQAFKLKMEKEYEKLKANEKKIEVEFGAYVQGYIEYINTGEGDDRCYKFTTLQYFHRDLGL
Download Length: 432 bp
>T6371 NC_005126:c5646260-5645829 [Photorhabdus laumondii subsp. laumondii TTO1]
ATGATATTGCGCCAGATCAAACAAGATGTCTACAACAGGCTTTGTGAAAATAGACCGCAAGTTTTAGAAAAAAATAGGGG
GTATGGCGTTATATCGATTACTTTAAACGGACTTACATTCGCAGTCCCTTTACGAAGTAATCTAAATCATCCTAATGGGT
TCAAGACTATCTTCATAAAGGAAAAAAAATGCTGGAGTGGCTTAGATTACTCAAAAGCTTTACTCATTGATGTTGATGAT
CTAGAACCACAAGCTTTTAAGCTAAAAATGGAAAAAGAGTATGAAAAGTTAAAAGCAAACGAAAAAAAGATCGAGGTGGA
ATTTGGGGCTTATGTTCAAGGATACATTGAATACATAAATACTGGTGAGGGTGATGATCGTTGTTATAAATTTACTACAC
TCCAGTATTTCCATAGAGATTTGGGCTTATAG
ATGATATTGCGCCAGATCAAACAAGATGTCTACAACAGGCTTTGTGAAAATAGACCGCAAGTTTTAGAAAAAAATAGGGG
GTATGGCGTTATATCGATTACTTTAAACGGACTTACATTCGCAGTCCCTTTACGAAGTAATCTAAATCATCCTAATGGGT
TCAAGACTATCTTCATAAAGGAAAAAAAATGCTGGAGTGGCTTAGATTACTCAAAAGCTTTACTCATTGATGTTGATGAT
CTAGAACCACAAGCTTTTAAGCTAAAAATGGAAAAAGAGTATGAAAAGTTAAAAGCAAACGAAAAAAAGATCGAGGTGGA
ATTTGGGGCTTATGTTCAAGGATACATTGAATACATAAATACTGGTGAGGGTGATGATCGTTGTTATAAATTTACTACAC
TCCAGTATTTCCATAGAGATTTGGGCTTATAG
Antitoxin
Download Length: 50 bp
>AT6371 NC_005126:c5646368-5646319 [Photorhabdus laumondii subsp. laumondii TTO1]
GATTATGTGGCGGTAGAGGCATCCCCACGTTAAATAGAACAACCTCATTG
GATTATGTGGCGGTAGAGGCATCCCCACGTTAAATAGAACAACCTCATTG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
References
(1) Tim R Blower et al. (2012) Identification and classification of bacterial Type III toxin-antitoxin systems encoded in chromosomal and plasmid genomes. Nucleic Acids Research 40(13):6158-73. [PubMed:22434880]