Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2556147..2556418 Replicon chromosome
Accession NZ_CP015843
Organism Escherichia coli O157:H7 strain FRIK2455

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2556185..2556288 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2556147..2556418 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A8V32_RS13950 2553304..2554743 + 1440 WP_064261958.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
A8V32_RS13955 2554861..2555097 + 237 WP_001295499.1 DUF1480 family protein -
A8V32_RS13960 2555202..2555393 + 192 WP_001296140.1 YebW family protein -
A8V32_RS13965 2555394..2556050 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 2556147..2556418 + 272 - - Antitoxin
- 2556185..2556288 - 104 - - Toxin
A8V32_RS13970 2556446..2556787 - 342 WP_000976483.1 YebY family protein -
A8V32_RS13975 2556800..2557672 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
A8V32_RS13980 2557676..2558050 - 375 WP_000168751.1 CopC domain-containing protein YobA -
A8V32_RS13985 2558189..2558419 + 231 WP_000916763.1 DNA polymerase III subunit theta -
A8V32_RS13990 2558521..2559177 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
A8V32_RS13995 2559201..2559863 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T63703 NZ_CP015843:c2556288-2556185 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT63703 NZ_CP015843:2556147-2556418 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References