Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2556138..2556409 Replicon chromosome
Accession NZ_CP015842
Organism Escherichia coli O157:H7 strain FRIK2533

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2556176..2556279 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2556138..2556409 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A8V31_RS13940 2553295..2554734 + 1440 WP_064261958.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
A8V31_RS13945 2554852..2555088 + 237 WP_001295499.1 DUF1480 family protein -
A8V31_RS13950 2555193..2555384 + 192 WP_001296140.1 YebW family protein -
A8V31_RS13955 2555385..2556041 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 2556138..2556409 + 272 - - Antitoxin
- 2556176..2556279 - 104 - - Toxin
A8V31_RS13960 2556437..2556790 - 354 WP_000384361.1 YebY family protein -
A8V31_RS13965 2556790..2557662 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
A8V31_RS13970 2557666..2558040 - 375 WP_000168751.1 CopC domain-containing protein YobA -
A8V31_RS13975 2558178..2558408 + 231 WP_000916763.1 DNA polymerase III subunit theta -
A8V31_RS13980 2558510..2559166 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
A8V31_RS13985 2559190..2559852 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T63661 NZ_CP015842:c2556279-2556176 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT63661 NZ_CP015842:2556138-2556409 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References