Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2353677..2353948 | Replicon | chromosome |
| Accession | NZ_CP015831 | ||
| Organism | Escherichia coli O157 strain 644-PT8 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2353807..2353910 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2353677..2353948 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A8L40_RS12200 | 2350232..2350894 | - | 663 | WP_000944243.1 | exodeoxyribonuclease X | - |
| A8L40_RS12205 | 2350918..2351574 | - | 657 | WP_000011656.1 | carbon-nitrogen hydrolase family protein | - |
| A8L40_RS12210 | 2351676..2351906 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| A8L40_RS12215 | 2352045..2352419 | + | 375 | WP_000168751.1 | CopC domain-containing protein YobA | - |
| A8L40_RS12220 | 2352423..2353295 | + | 873 | WP_000879314.1 | copper homeostasis membrane protein CopD | - |
| A8L40_RS12225 | 2353308..2353649 | + | 342 | WP_000976483.1 | YebY family protein | - |
| - | 2353677..2353948 | - | 272 | - | - | Antitoxin |
| - | 2353807..2353910 | + | 104 | - | - | Toxin |
| A8L40_RS12235 | 2354045..2354701 | + | 657 | WP_032106700.1 | protein-serine/threonine phosphatase | - |
| A8L40_RS12240 | 2354702..2354893 | - | 192 | WP_001296140.1 | YebW family protein | - |
| A8L40_RS12245 | 2354998..2355234 | - | 237 | WP_001295499.1 | DUF1480 family protein | - |
| A8L40_RS12250 | 2355352..2356791 | - | 1440 | WP_001302304.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T63528 NZ_CP015831:2353807-2353910 [Escherichia coli O157]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT63528 NZ_CP015831:c2353948-2353677 [Escherichia coli O157]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
