Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1566009..1566154 Replicon chromosome
Accession NZ_CP015822
Organism Klebsiella pneumoniae isolate blood sample

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1566016..1566118 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1566009..1566154 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A8N26_RS08020 1561541..1562974 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
A8N26_RS08025 1563090..1563329 + 240 WP_002911393.1 YebV family protein -
A8N26_RS08030 1563427..1563618 + 192 WP_002911395.1 YebW family protein -
A8N26_RS08035 1563615..1564268 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
A8N26_RS08040 1564425..1565393 + 969 WP_004151446.1 VirK/YbjX family protein -
A8N26_RS31595 1565498..1565641 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1566009..1566154 + 146 - - Antitoxin
- 1566016..1566118 - 103 - - Toxin
A8N26_RS08050 1566277..1566615 - 339 WP_002911404.1 YebY family protein -
A8N26_RS08055 1566632..1567501 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
A8N26_RS08060 1567505..1567879 - 375 WP_004151448.1 CopC domain-containing protein YobA -
A8N26_RS08065 1567992..1568222 + 231 WP_002911406.1 DNA polymerase III subunit theta -
A8N26_RS08070 1568301..1568960 + 660 WP_002911407.1 exodeoxyribonuclease X -
A8N26_RS08075 1568964..1571024 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T63499 NZ_CP015822:c1566118-1566016 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT63499 NZ_CP015822:1566009-1566154 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References