Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2580230..2580696 Replicon chromosome
Accession NZ_CP015821
Organism Bartonella apis strain BBC0244

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BBC0244_RS11465 Protein ID WP_077973295.1
Coordinates 2580490..2580696 (+) Length 69 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BBC0244_RS11460 Protein ID WP_077973293.1
Coordinates 2580230..2580502 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BBC0244_RS11445 2575980..2576684 - 705 WP_077973287.1 acetolactate decarboxylase -
BBC0244_RS11450 2578155..2579240 + 1086 WP_077973289.1 site-specific integrase -
BBC0244_RS11455 2579439..2580170 + 732 WP_077973291.1 hypothetical protein -
BBC0244_RS11460 2580230..2580502 + 273 WP_077973293.1 CopG family ribbon-helix-helix protein Antitoxin
BBC0244_RS11465 2580490..2580696 + 207 WP_077973295.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BBC0244_RS11470 2580716..2581381 - 666 WP_077973297.1 hypothetical protein -
BBC0244_RS11475 2581520..2582098 - 579 WP_077973298.1 recombinase family protein -
BBC0244_RS11480 2582273..2583910 + 1638 WP_149867613.1 RNA-directed DNA polymerase -
BBC0244_RS11485 2584324..2584797 - 474 WP_077971366.1 hypothetical protein -
BBC0244_RS11490 2584808..2584999 - 192 WP_077971365.1 hypothetical protein -
BBC0244_RS11495 2584996..2585334 - 339 WP_149867614.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2571829..2583910 12081


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-57)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 69 a.a.        Molecular weight: 7696.18 Da        Isoelectric Point: 10.3943

>T63497 WP_077973295.1 NZ_CP015821:2580490-2580696 [Bartonella apis]
MSKIILTEVAVQGLDKCRRFLSRKAPQEAKRAAKAIQDQLLILAKTPQIGQPIEEVLELRKLLIPFND

Download         Length: 207 bp

>T63497 NZ_CP015821:2580490-2580696 [Bartonella apis]
ATGTCAAAAATAATACTTACTGAAGTCGCCGTTCAAGGCTTAGATAAGTGTCGCCGCTTTTTATCACGAAAAGCTCCGCA
AGAAGCGAAGCGTGCAGCTAAAGCAATTCAAGATCAATTACTAATTTTGGCGAAAACACCACAAATAGGTCAACCAATCG
AAGAAGTGTTGGAATTAAGAAAATTGCTCATTCCCTTTAATGATTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10560.67 Da        Isoelectric Point: 5.1800

>AT63497 WP_077973293.1 NZ_CP015821:2580230-2580502 [Bartonella apis]
MATSLKIDDALKSRVHNLADQRRRSAHWIMLEAIQQYVDREEQREAFKQEALDSWESFQETGQHITGKEARDWLDTWGTE
NETAAPKCQK

Download         Length: 273 bp

>AT63497 NZ_CP015821:2580230-2580502 [Bartonella apis]
ATGGCAACTTCATTGAAGATTGATGACGCTTTAAAATCTCGTGTTCATAATCTGGCAGACCAAAGGCGGCGTTCTGCTCA
CTGGATTATGCTTGAGGCTATCCAGCAATATGTTGACCGCGAAGAACAGCGTGAAGCCTTCAAACAGGAGGCTTTAGATT
CGTGGGAAAGTTTTCAGGAAACTGGACAGCATATCACAGGAAAAGAAGCACGTGATTGGTTGGATACATGGGGAACTGAA
AACGAAACGGCTGCGCCTAAATGTCAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References