Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 844966..845111 Replicon chromosome
Accession NZ_CP015753
Organism Klebsiella pneumoniae strain W14

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 844973..845075 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 844966..845111 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7321_RS04275 840498..841931 + 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
A7321_RS04280 842047..842286 + 240 WP_002911393.1 YebV family protein -
A7321_RS04285 842384..842575 + 192 WP_002911395.1 YebW family protein -
A7321_RS04290 842572..843225 - 654 WP_064081141.1 protein-serine/threonine phosphatase -
A7321_RS04295 843382..844350 + 969 WP_004151446.1 VirK/YbjX family protein -
A7321_RS28680 844455..844598 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 844966..845111 + 146 - - Antitoxin
- 844973..845075 - 103 - - Toxin
A7321_RS04305 845234..845572 - 339 WP_002911404.1 YebY family protein -
A7321_RS04310 845589..846458 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
A7321_RS04315 846462..846836 - 375 WP_004151448.1 CopC domain-containing protein YobA -
A7321_RS04320 846949..847179 + 231 WP_002911406.1 DNA polymerase III subunit theta -
A7321_RS04325 847258..847917 + 660 WP_002911407.1 exodeoxyribonuclease X -
A7321_RS04330 847921..849981 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T63355 NZ_CP015753:c845075-844973 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT63355 NZ_CP015753:844966-845111 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References