Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | tacT-ataR/DUF1778(antitoxin) |
| Location | 2259348..2260090 | Replicon | chromosome |
| Accession | NZ_CP015750 | ||
| Organism | Pectobacterium wasabiae CFBP 3304 | ||
Toxin (Protein)
| Gene name | tacT | Uniprot ID | A0A1D7Z1H7 |
| Locus tag | A7983_RS10260 | Protein ID | WP_005973620.1 |
| Coordinates | 2259348..2259827 (-) | Length | 160 a.a. |
Antitoxin (Protein)
| Gene name | ataR | Uniprot ID | A0A1D7Z1H8 |
| Locus tag | A7983_RS10265 | Protein ID | WP_005973618.1 |
| Coordinates | 2259818..2260090 (-) | Length | 91 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A7983_RS10225 | 2255128..2255388 | + | 261 | WP_005973638.1 | AlpA family transcriptional regulator | - |
| A7983_RS10230 | 2255385..2255609 | + | 225 | WP_005973635.1 | hypothetical protein | - |
| A7983_RS23900 | 2255618..2256007 | + | 390 | Protein_2017 | ash family protein | - |
| A7983_RS23905 | 2255971..2256168 | + | 198 | WP_005973632.1 | host cell division inhibitor Icd-like protein | - |
| A7983_RS10240 | 2256161..2256355 | + | 195 | WP_005973630.1 | hypothetical protein | - |
| A7983_RS10245 | 2256352..2256618 | + | 267 | WP_005973627.1 | hypothetical protein | - |
| A7983_RS10250 | 2256615..2256956 | + | 342 | WP_005973624.1 | DUF5375 family protein | - |
| A7983_RS10255 | 2256967..2259294 | + | 2328 | WP_005973622.1 | toprim domain-containing protein | - |
| A7983_RS10260 | 2259348..2259827 | - | 480 | WP_005973620.1 | GNAT family N-acetyltransferase | Toxin |
| A7983_RS10265 | 2259818..2260090 | - | 273 | WP_005973618.1 | DUF1778 domain-containing protein | Antitoxin |
| A7983_RS10270 | 2260381..2260632 | + | 252 | WP_005973616.1 | prevent-host-death protein | - |
| A7983_RS10275 | 2260622..2260906 | + | 285 | WP_005973612.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| A7983_RS10280 | 2261521..2262774 | + | 1254 | WP_005973610.1 | tyrosine-type recombinase/integrase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2248984..2281587 | 32603 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 160 a.a. Molecular weight: 17504.13 Da Isoelectric Point: 8.9715
>T63349 WP_005973620.1 NZ_CP015750:c2259827-2259348 [Pectobacterium wasabiae CFBP 3304]
VGITAPELLLPQHAVVDFRSSEPSLDDWLKRKALKNQTMGASRTFVVCESSANQVIGFYALATGSVQRQSVSGALRRNMP
DPLPVLVLGRLAVDERYHRQGIGAGLLKDAILRSRQVAEQVGTKALLVHALSEDAKDFYLHWGFTSSEIQPNTLLLPLW
VGITAPELLLPQHAVVDFRSSEPSLDDWLKRKALKNQTMGASRTFVVCESSANQVIGFYALATGSVQRQSVSGALRRNMP
DPLPVLVLGRLAVDERYHRQGIGAGLLKDAILRSRQVAEQVGTKALLVHALSEDAKDFYLHWGFTSSEIQPNTLLLPLW
Download Length: 480 bp
>T63349 NZ_CP015750:c2259827-2259348 [Pectobacterium wasabiae CFBP 3304]
GTGGGAATAACGGCACCTGAATTATTATTACCTCAGCATGCCGTGGTTGATTTCCGAAGTTCAGAACCGTCACTGGATGA
CTGGCTGAAGCGTAAGGCGCTCAAGAATCAAACCATGGGCGCATCACGCACTTTTGTCGTGTGTGAATCGAGTGCTAATC
AGGTTATTGGCTTTTACGCGCTGGCAACCGGCAGCGTACAGCGCCAATCCGTATCGGGTGCGTTACGACGCAATATGCCT
GATCCGCTGCCCGTATTAGTCTTGGGTCGTCTGGCGGTAGATGAACGTTATCACCGTCAGGGGATTGGCGCGGGACTATT
AAAAGATGCGATCTTGCGTTCCCGGCAGGTTGCTGAACAGGTGGGAACGAAAGCGTTATTAGTTCATGCGCTGTCTGAGG
ACGCAAAAGATTTTTATCTGCATTGGGGCTTTACGTCCTCGGAAATCCAGCCTAACACATTGCTTCTACCACTCTGGTAA
GTGGGAATAACGGCACCTGAATTATTATTACCTCAGCATGCCGTGGTTGATTTCCGAAGTTCAGAACCGTCACTGGATGA
CTGGCTGAAGCGTAAGGCGCTCAAGAATCAAACCATGGGCGCATCACGCACTTTTGTCGTGTGTGAATCGAGTGCTAATC
AGGTTATTGGCTTTTACGCGCTGGCAACCGGCAGCGTACAGCGCCAATCCGTATCGGGTGCGTTACGACGCAATATGCCT
GATCCGCTGCCCGTATTAGTCTTGGGTCGTCTGGCGGTAGATGAACGTTATCACCGTCAGGGGATTGGCGCGGGACTATT
AAAAGATGCGATCTTGCGTTCCCGGCAGGTTGCTGAACAGGTGGGAACGAAAGCGTTATTAGTTCATGCGCTGTCTGAGG
ACGCAAAAGATTTTTATCTGCATTGGGGCTTTACGTCCTCGGAAATCCAGCCTAACACATTGCTTCTACCACTCTGGTAA
Antitoxin
Download Length: 91 a.a. Molecular weight: 10306.80 Da Isoelectric Point: 4.7174
>AT63349 WP_005973618.1 NZ_CP015750:c2260090-2259818 [Pectobacterium wasabiae CFBP 3304]
MRTEAKEAPINIRAKSSQRELIDVAAKMLSKSRTDFILEAACREAEEVLLDQRLFLVDESQFDAFITALEKPVATNERLQ
ALLDRKSPWE
MRTEAKEAPINIRAKSSQRELIDVAAKMLSKSRTDFILEAACREAEEVLLDQRLFLVDESQFDAFITALEKPVATNERLQ
ALLDRKSPWE
Download Length: 273 bp
>AT63349 NZ_CP015750:c2260090-2259818 [Pectobacterium wasabiae CFBP 3304]
ATGAGAACAGAGGCAAAAGAGGCACCGATCAACATTAGGGCGAAATCATCACAACGGGAACTGATAGACGTTGCCGCGAA
AATGCTTTCAAAGTCACGTACTGATTTTATCCTTGAGGCTGCATGTCGTGAGGCGGAAGAGGTGCTATTGGATCAACGCC
TGTTTCTGGTTGATGAATCACAATTTGATGCCTTTATTACCGCGTTAGAAAAACCTGTCGCCACCAATGAGCGGTTACAG
GCGTTATTAGACAGGAAATCACCGTGGGAATAA
ATGAGAACAGAGGCAAAAGAGGCACCGATCAACATTAGGGCGAAATCATCACAACGGGAACTGATAGACGTTGCCGCGAA
AATGCTTTCAAAGTCACGTACTGATTTTATCCTTGAGGCTGCATGTCGTGAGGCGGAAGAGGTGCTATTGGATCAACGCC
TGTTTCTGGTTGATGAATCACAATTTGATGCCTTTATTACCGCGTTAGAAAAACCTGTCGCCACCAATGAGCGGTTACAG
GCGTTATTAGACAGGAAATCACCGTGGGAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A1D7Z1H7 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A1D7Z1H8 |