Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 2152329..2152860 Replicon chromosome
Accession NZ_CP015750
Organism Pectobacterium wasabiae CFBP 3304

Toxin (Protein)


Gene name stbE Uniprot ID A0A1D7Z189
Locus tag A7983_RS09750 Protein ID WP_005975534.1
Coordinates 2152573..2152860 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID Q6DAD0
Locus tag A7983_RS09745 Protein ID WP_005975532.1
Coordinates 2152329..2152583 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7983_RS09720 2147781..2148371 - 591 WP_005975525.1 DnaA initiator-associating protein DiaA -
A7983_RS09725 2148413..2148769 - 357 WP_172645151.1 YraN family protein -
A7983_RS09730 2148766..2150772 - 2007 WP_005975529.1 penicillin-binding protein activator -
A7983_RS09735 2150834..2151721 + 888 WP_005975531.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
A7983_RS09745 2152329..2152583 + 255 WP_005975532.1 hypothetical protein Antitoxin
A7983_RS09750 2152573..2152860 + 288 WP_005975534.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A7983_RS09755 2153039..2153824 + 786 WP_005975536.1 4,5-DOPA dioxygenase extradiol -
A7983_RS09760 2153893..2155053 - 1161 WP_005975538.1 glutathionylspermidine synthase family protein -
A7983_RS09765 2155065..2155733 - 669 WP_005975541.1 DUF1190 family protein -
A7983_RS09770 2156016..2157407 - 1392 WP_005975544.1 outer membrane channel protein TolC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-77)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11125.04 Da        Isoelectric Point: 10.7131

>T63347 WP_005975534.1 NZ_CP015750:2152573-2152860 [Pectobacterium wasabiae CFBP 3304]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLAERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDDTITVMVMGVGR
REGNQIYSDTKDRSI

Download         Length: 288 bp

>T63347 NZ_CP015750:2152573-2152860 [Pectobacterium wasabiae CFBP 3304]
ATGACTTATAAGTTGAAATTTGTTCCTTCTGCAATGAAGGAATGGAAAAAGTTAGGGCATCCTGTTCGGGAACAATTCAA
GAAGAAGTTGGCCGAGCGCCTAGAGAATCCTCGTGTTCCTTCGGCTCAGCTTCATGGTCGCAAAGATCAGTATAAAATTA
AACTGAAGTCTGCTGGCTACAGACTGGTGTATTTAGTTCAGGATGACACCATTACTGTAATGGTTATGGGGGTTGGAAGG
CGTGAAGGAAACCAGATTTATTCTGATACTAAAGATCGGTCTATTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9246.47 Da        Isoelectric Point: 3.9487

>AT63347 WP_005975532.1 NZ_CP015750:2152329-2152583 [Pectobacterium wasabiae CFBP 3304]
MAFNILTNTAASITELKRDPMGTVRSAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGHTVDERMSEIVDAKEIS
LDDL

Download         Length: 255 bp

>AT63347 NZ_CP015750:2152329-2152583 [Pectobacterium wasabiae CFBP 3304]
ATGGCTTTCAACATCCTAACTAATACAGCAGCCAGTATCACTGAGTTGAAACGTGATCCAATGGGGACGGTGCGGTCTGC
TGAAGGTGAAACTATCGCTATACTGAACCGCAATGAGCCTGCGTTCTATTGCGTGCCTCCTGCCGTATTCGCTTACTTGA
TGGAACTCGCTGAAGATGCAGAATTGGGGCATACCGTCGATGAGCGGATGTCAGAGATAGTTGATGCGAAAGAGATTTCG
CTCGATGACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z189

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z173

References