Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
Location | 3570950..3571986 | Replicon | chromosome |
Accession | NZ_CP015749 | ||
Organism | Pectobacterium parmentieri strain RNS 08-42-1A |
Toxin (Protein)
Gene name | PP_4152 | Uniprot ID | A0A8B3FNB9 |
Locus tag | A8F97_RS16170 | Protein ID | WP_033070784.1 |
Coordinates | 3570950..3571525 (-) | Length | 192 a.a. |
Antitoxin (Protein)
Gene name | PP_4151 | Uniprot ID | A0A8B3FHU5 |
Locus tag | A8F97_RS16175 | Protein ID | WP_033070783.1 |
Coordinates | 3571525..3571986 (-) | Length | 154 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
A8F97_RS16155 | 3566771..3568033 | - | 1263 | WP_033070786.1 | integrase arm-type DNA-binding domain-containing protein | - |
A8F97_RS23420 | 3568575..3568787 | + | 213 | WP_082218588.1 | DUF1133 family protein | - |
A8F97_RS16160 | 3568849..3569673 | + | 825 | WP_127087856.1 | hypothetical protein | - |
A8F97_RS16165 | 3569660..3570781 | + | 1122 | WP_033070785.1 | XRE family transcriptional regulator | - |
A8F97_RS16170 | 3570950..3571525 | - | 576 | WP_033070784.1 | PIN domain-containing protein | Toxin |
A8F97_RS16175 | 3571525..3571986 | - | 462 | WP_033070783.1 | helix-turn-helix domain-containing protein | Antitoxin |
A8F97_RS23425 | 3572291..3572509 | + | 219 | Protein_3224 | hypothetical protein | - |
A8F97_RS23435 | 3572678..3572752 | - | 75 | Protein_3225 | type II toxin-antitoxin system RelE/ParE family toxin | - |
A8F97_RS24195 | 3572967..3573218 | + | 252 | WP_127087855.1 | hypothetical protein | - |
A8F97_RS16185 | 3573765..3574643 | + | 879 | WP_033070781.1 | integrase domain-containing protein | - |
A8F97_RS16190 | 3574646..3574846 | + | 201 | WP_014698606.1 | AlpA family transcriptional regulator | - |
A8F97_RS23440 | 3574843..3575379 | + | 537 | WP_033070780.1 | ash family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 3564060..3581066 | 17006 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21771.27 Da Isoelectric Point: 4.8050
>T63340 WP_033070784.1 NZ_CP015749:c3571525-3570950 [Pectobacterium parmentieri]
MNHSPYPVVLDACVIYPNMLRDLLMEVGKSGLYQPKWTATIHDEWQRNLVENVPDLTREKLKRVEDLMNKALPDALVTGF
ENLMEGVSLPDLDDRHVVAAAIRSDSEVIVTFNLKDFPKESLAEFDIEAIHPDEFIADLLDLNQALVLQAVQRQRARLKN
PKKSVDEYFDILLKLGLPMTVKAITAYKLMI
MNHSPYPVVLDACVIYPNMLRDLLMEVGKSGLYQPKWTATIHDEWQRNLVENVPDLTREKLKRVEDLMNKALPDALVTGF
ENLMEGVSLPDLDDRHVVAAAIRSDSEVIVTFNLKDFPKESLAEFDIEAIHPDEFIADLLDLNQALVLQAVQRQRARLKN
PKKSVDEYFDILLKLGLPMTVKAITAYKLMI
Download Length: 576 bp
>T63340 NZ_CP015749:c3571525-3570950 [Pectobacterium parmentieri]
ATGAATCATTCGCCTTACCCAGTCGTACTTGATGCCTGTGTCATTTATCCCAACATGCTCCGCGATCTGCTTATGGAGGT
TGGGAAATCGGGTCTGTATCAACCTAAATGGACGGCCACCATTCATGATGAATGGCAAAGAAATTTGGTTGAAAACGTAC
CGGATTTAACGCGTGAAAAATTGAAGCGCGTAGAGGATCTGATGAACAAAGCCCTACCTGATGCTCTTGTAACGGGCTTT
GAAAATCTTATGGAAGGGGTTTCACTCCCAGATCTTGACGATCGCCATGTTGTAGCTGCAGCGATAAGATCCGATTCAGA
GGTGATCGTAACCTTCAATCTTAAAGACTTTCCAAAGGAGAGCCTGGCTGAGTTTGATATTGAAGCAATTCATCCTGATG
AGTTTATCGCTGATTTGCTGGATTTAAATCAAGCCTTAGTTTTACAGGCTGTCCAAAGGCAGCGAGCCCGGCTAAAGAAC
CCCAAAAAATCAGTAGATGAATATTTCGACATACTACTGAAACTAGGCTTGCCGATGACGGTTAAGGCTATAACTGCTTA
TAAATTAATGATTTAG
ATGAATCATTCGCCTTACCCAGTCGTACTTGATGCCTGTGTCATTTATCCCAACATGCTCCGCGATCTGCTTATGGAGGT
TGGGAAATCGGGTCTGTATCAACCTAAATGGACGGCCACCATTCATGATGAATGGCAAAGAAATTTGGTTGAAAACGTAC
CGGATTTAACGCGTGAAAAATTGAAGCGCGTAGAGGATCTGATGAACAAAGCCCTACCTGATGCTCTTGTAACGGGCTTT
GAAAATCTTATGGAAGGGGTTTCACTCCCAGATCTTGACGATCGCCATGTTGTAGCTGCAGCGATAAGATCCGATTCAGA
GGTGATCGTAACCTTCAATCTTAAAGACTTTCCAAAGGAGAGCCTGGCTGAGTTTGATATTGAAGCAATTCATCCTGATG
AGTTTATCGCTGATTTGCTGGATTTAAATCAAGCCTTAGTTTTACAGGCTGTCCAAAGGCAGCGAGCCCGGCTAAAGAAC
CCCAAAAAATCAGTAGATGAATATTTCGACATACTACTGAAACTAGGCTTGCCGATGACGGTTAAGGCTATAACTGCTTA
TAAATTAATGATTTAG
Antitoxin
Download Length: 154 a.a. Molecular weight: 17321.80 Da Isoelectric Point: 6.1440
>AT63340 WP_033070783.1 NZ_CP015749:c3571986-3571525 [Pectobacterium parmentieri]
MTSSILDNVSLPAQKEIEVALRGQRELATFLTTKFETQKISIHDANDEKHQIELPTSALRLLMNILGELAEGNAVQVVPV
HAELTTQEAANILNVSRPHMVKLLEEGKLPHHKTGRHRRVLFADLMRYKAQRETESNEAMQELVDLSQELGFY
MTSSILDNVSLPAQKEIEVALRGQRELATFLTTKFETQKISIHDANDEKHQIELPTSALRLLMNILGELAEGNAVQVVPV
HAELTTQEAANILNVSRPHMVKLLEEGKLPHHKTGRHRRVLFADLMRYKAQRETESNEAMQELVDLSQELGFY
Download Length: 462 bp
>AT63340 NZ_CP015749:c3571986-3571525 [Pectobacterium parmentieri]
ATGACTAGCTCAATTCTGGACAATGTAAGCCTTCCGGCTCAGAAGGAAATTGAGGTTGCGTTACGTGGACAAAGAGAACT
GGCAACATTTCTCACCACAAAGTTCGAAACGCAAAAAATATCGATTCACGATGCAAACGACGAAAAACACCAGATCGAAT
TGCCAACCTCAGCACTGAGATTGCTAATGAACATCTTGGGTGAACTCGCTGAAGGGAACGCGGTTCAAGTTGTCCCTGTG
CACGCTGAATTAACTACACAGGAGGCCGCCAATATTCTGAATGTTTCACGCCCTCACATGGTGAAGCTTTTAGAAGAAGG
AAAGCTTCCACATCATAAAACAGGCCGTCATCGCCGCGTTCTTTTTGCTGATTTGATGCGCTATAAAGCTCAGCGTGAAA
CTGAGAGCAATGAAGCAATGCAAGAACTGGTTGATTTGAGCCAGGAACTTGGTTTTTATTAA
ATGACTAGCTCAATTCTGGACAATGTAAGCCTTCCGGCTCAGAAGGAAATTGAGGTTGCGTTACGTGGACAAAGAGAACT
GGCAACATTTCTCACCACAAAGTTCGAAACGCAAAAAATATCGATTCACGATGCAAACGACGAAAAACACCAGATCGAAT
TGCCAACCTCAGCACTGAGATTGCTAATGAACATCTTGGGTGAACTCGCTGAAGGGAACGCGGTTCAAGTTGTCCCTGTG
CACGCTGAATTAACTACACAGGAGGCCGCCAATATTCTGAATGTTTCACGCCCTCACATGGTGAAGCTTTTAGAAGAAGG
AAAGCTTCCACATCATAAAACAGGCCGTCATCGCCGCGTTCTTTTTGCTGATTTGATGCGCTATAAAGCTCAGCGTGAAA
CTGAGAGCAATGAAGCAATGCAAGAACTGGTTGATTTGAGCCAGGAACTTGGTTTTTATTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A8B3FNB9 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A8B3FHU5 |