63334

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 570942..571569 Replicon chromosome
Accession NZ_CP015749
Organism Pectobacterium parmentieri strain RNS 08-42-1A

Toxin (Protein)


Gene name Hha Uniprot ID C6DB72
Locus tag A8F97_RS02425 Protein ID WP_005976087.1
Coordinates 570942..571145 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID C6DB73
Locus tag A8F97_RS02430 Protein ID WP_005976089.1
Coordinates 571201..571569 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A8F97_RS02395 566433..566771 + 339 WP_002208627.1 P-II family nitrogen regulator -
A8F97_RS02400 566811..568097 + 1287 WP_014700821.1 ammonium transporter AmtB -
A8F97_RS02405 568215..569078 - 864 WP_014700820.1 acyl-CoA thioesterase II -
A8F97_RS02410 569289..569873 + 585 WP_033071821.1 YbaY family lipoprotein -
A8F97_RS02415 569893..570213 - 321 WP_005976085.1 MGMT family protein -
A8F97_RS02425 570942..571145 - 204 WP_005976087.1 hemolysin expression modulator Hha Toxin
A8F97_RS02430 571201..571569 - 369 WP_005976089.1 Hha toxicity modulator TomB Antitoxin
A8F97_RS22890 572328..572471 - 144 WP_005976091.1 type B 50S ribosomal protein L36 -
A8F97_RS02435 572489..572737 - 249 WP_015730970.1 type B 50S ribosomal protein L31 -
A8F97_RS02440 572970..576098 - 3129 WP_033071820.1 multidrug efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8145.52 Da        Isoelectric Point: 8.9008

>T63334 WP_005976087.1 NZ_CP015749:c571145-570942 [Pectobacterium parmentieri]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFFSAADHRLAELTMNKLYDKVPTAVWRYVR

Download         Length: 204 bp

>T63334 NZ_CP015749:c571145-570942 [Pectobacterium parmentieri]
ATGAAAAAAATCGACTATTTGATGCGTTTGCGTAAATGCACAACGATTGACACTCTCGAACGCGTTATTGAAAAAAACAA
GTATGAACTCTCCAATGATGAACTGGAGATGTTCTTTTCTGCAGCCGATCATCGCCTCGCAGAGTTGACGATGAACAAAC
TCTACGACAAAGTTCCTACCGCAGTATGGCGATACGTCCGTTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14032.77 Da        Isoelectric Point: 4.4787

>AT63334 WP_005976089.1 NZ_CP015749:c571569-571201 [Pectobacterium parmentieri]
MDEYTPKHYDIAQLRFLCENLCDESIATLGDSSHGWVNDPTSAINLQLNELIEHIATFILTFKIKYPNESELSEQVEKYL
DDTYVLFSNYGINDAELRRWQKSKAKLFGMFSGENVCTPAKT

Download         Length: 369 bp

>AT63334 NZ_CP015749:c571569-571201 [Pectobacterium parmentieri]
ATGGATGAGTACACACCAAAGCATTATGATATTGCCCAACTCAGATTCTTATGTGAGAATCTGTGTGATGAGAGCATAGC
AACGTTAGGCGATAGCAGTCACGGCTGGGTCAATGATCCAACTTCTGCGATCAATCTCCAATTAAATGAGCTTATTGAGC
ATATCGCTACGTTTATTCTCACATTTAAAATAAAATACCCTAACGAAAGTGAGCTCTCAGAGCAGGTTGAAAAATATTTG
GATGATACTTACGTCTTGTTTAGCAACTATGGTATTAATGACGCTGAACTACGACGCTGGCAGAAGTCCAAAGCAAAATT
ATTCGGAATGTTCTCAGGGGAGAACGTCTGTACGCCTGCTAAAACTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z3F0

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z3G5

References