Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 696535..698003 Replicon chromosome
Accession NZ_CP015612
Organism Stenotrophomonas maltophilia strain OUC_Est10

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag A7326_RS03095 Protein ID WP_198360832.1
Coordinates 696535..697404 (-) Length 290 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag A7326_RS03100 Protein ID WP_088024269.1
Coordinates 697401..698003 (-) Length 201 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7326_RS03075 692685..693293 - 609 WP_088024257.1 metal-dependent hydrolase -
A7326_RS03080 693404..693799 - 396 WP_088024260.1 YraN family protein -
A7326_RS03085 693762..695483 - 1722 WP_088024264.1 penicillin-binding protein activator -
A7326_RS03090 695565..696383 + 819 WP_088024267.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
A7326_RS03095 696535..697404 - 870 WP_198360832.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
A7326_RS03100 697401..698003 - 603 WP_088024269.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
A7326_RS03110 698704..699183 - 480 WP_088024270.1 DM13 domain-containing protein -
A7326_RS03115 699285..700037 - 753 WP_088024271.1 NRDE family protein -
A7326_RS03120 700361..700807 + 447 WP_004143635.1 division/cell wall cluster transcriptional repressor MraZ -
A7326_RS03125 700822..701805 + 984 WP_088024273.1 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH -
A7326_RS03130 701802..702065 + 264 WP_005412242.1 cell division protein FtsL -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(40-268)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(11-53)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 32542.53 Da        Isoelectric Point: 8.2757

>T63243 WP_198360832.1 NZ_CP015612:c697404-696535 [Stenotrophomonas maltophilia]
MIPSPTPPHRVASIRQRLLDLARKRGEDFQFVLDRFAVERLLYRLSTSRYRNQFLLKGAMLFAVWFDAPHRPTRDADFLG
SGSAEPDRLLHIALSLCGMPGDDGLRFDPGSIVIEAIREEATYEGLRMRLIAHLGRARCHVQWDVGFGDAVITPPPEITY
PVILEGFPPACLRVYPRKTVFAEKLEAIAALGIANSRMKDFFDLLALIREDAMDRPHLVAAIGATFDRRRTPAPTPLPYG
LTQSFAADTQKQTQWRAFLRRNRLIAPDLSSVIAEIADYLDTLDTTVQS

Download         Length: 870 bp

>T63243 NZ_CP015612:c697404-696535 [Stenotrophomonas maltophilia]
TTGATCCCCTCTCCAACACCTCCCCACCGCGTTGCTTCCATCCGGCAACGGCTGCTCGATCTCGCACGCAAGCGGGGGGA
GGACTTTCAGTTCGTGCTGGACAGGTTCGCCGTTGAGCGCCTGCTCTACCGGCTCTCCACTTCTCGATACCGCAACCAGT
TCCTGCTGAAGGGTGCCATGCTGTTCGCAGTGTGGTTCGACGCGCCGCACCGCCCTACACGGGATGCCGATTTCCTGGGA
TCCGGCAGCGCTGAGCCCGATCGCCTGCTACATATCGCACTTTCGCTCTGTGGAATGCCCGGGGACGACGGCCTGCGCTT
CGATCCAGGCAGCATCGTCATCGAGGCCATACGTGAAGAAGCCACGTACGAGGGGCTGCGCATGCGCCTGATCGCACATC
TGGGCCGCGCACGCTGCCATGTGCAGTGGGACGTCGGCTTTGGCGACGCGGTGATCACCCCGCCGCCGGAAATCACCTAT
CCGGTGATTCTGGAGGGATTCCCTCCAGCCTGCCTGCGCGTCTATCCACGCAAAACCGTGTTTGCCGAAAAGCTCGAGGC
TATAGCGGCACTGGGCATCGCTAACAGCAGGATGAAGGACTTCTTCGACTTGCTGGCACTGATCCGCGAAGACGCCATGG
ATCGCCCGCACCTTGTTGCGGCCATTGGCGCGACGTTTGATCGACGAAGGACCCCGGCGCCAACGCCCCTGCCCTACGGA
CTGACTCAGTCATTCGCCGCAGATACCCAGAAGCAGACCCAGTGGCGCGCCTTCCTGCGCAGGAATCGCCTGATCGCGCC
GGATCTTTCTTCGGTGATTGCCGAGATTGCCGACTATCTGGACACCCTCGACACAACCGTACAGTCCTGA

Antitoxin


Download         Length: 201 a.a.        Molecular weight: 22232.96 Da        Isoelectric Point: 11.2557

>AT63243 WP_088024269.1 NZ_CP015612:c698003-697401 [Stenotrophomonas maltophilia]
MGNAEAKARKLLRRAGTLRARELVTAGIARAQLTRLVEAGALIRLSRGVYALAERKSDDTDDGLRIIAERLPHPRLCLLS
ALRLHGLTTQAPFERWVSIGNSDRVPRIDWPPLRVVRMSATTLNAGLEERRVGGRLIYVSNAAKTVVDCFKFRNLVGLDV
ALEALRDALHSRATTPDALMEYARICRVARLMRPYLDALA

Download         Length: 603 bp

>AT63243 NZ_CP015612:c698003-697401 [Stenotrophomonas maltophilia]
ATGGGAAACGCCGAGGCCAAGGCACGAAAGCTATTGCGACGCGCAGGCACCCTGCGCGCCCGCGAACTGGTGACTGCCGG
GATCGCCCGCGCCCAACTGACCCGCCTGGTCGAGGCAGGCGCACTGATCCGGTTGTCCCGTGGCGTCTACGCGTTGGCGG
AAAGAAAGAGCGACGACACCGATGATGGACTGCGGATCATTGCAGAACGCCTGCCACACCCCCGTCTGTGCCTGTTGAGT
GCCCTGCGCCTGCATGGCCTGACCACCCAGGCACCATTCGAACGCTGGGTTTCCATCGGCAACAGCGACCGCGTTCCGCG
GATCGACTGGCCGCCCCTCCGTGTGGTCCGCATGTCGGCAACGACCCTCAATGCGGGGCTGGAAGAACGTCGCGTAGGCG
GACGTCTCATATACGTCAGCAACGCAGCCAAAACCGTCGTCGATTGCTTCAAGTTCCGCAATCTCGTAGGGCTCGATGTC
GCACTTGAAGCCCTGCGTGACGCGCTTCACAGCCGTGCAACCACGCCGGATGCGTTGATGGAGTATGCGCGGATCTGCCG
CGTTGCCAGACTGATGAGACCGTACCTCGATGCCCTGGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References