Detailed information of TA system TA063243

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 696535..698003
• Replicon: chromosome
• Accession: NZ_CP015612
• Organism: Stenotrophomonas maltophilia strain OUC_Est10

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: A7326_RS03095
• Protein ID: WP_198360832.1
• Coordinates: 696535..697404 (-)
• Length: 290 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: A7326_RS03100
• Protein ID: WP_088024269.1
• Coordinates: 697401..698003 (-)
• Length: 201 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A7326_RS03075	692685..693293	-	609	WP_088024257.1	metal-dependent hydrolase	-
A7326_RS03080	693404..693799	-	396	WP_088024260.1	YraN family protein	-
A7326_RS03085	693762..695483	-	1722	WP_088024264.1	penicillin-binding protein activator	-
A7326_RS03090	695565..696383	+	819	WP_088024267.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
A7326_RS03095	696535..697404	-	870	WP_198360832.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
A7326_RS03100	697401..698003	-	603	WP_088024269.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
A7326_RS03110	698704..699183	-	480	WP_088024270.1	DM13 domain-containing protein	-
A7326_RS03115	699285..700037	-	753	WP_088024271.1	NRDE family protein	-
A7326_RS03120	700361..700807	+	447	WP_004143635.1	division/cell wall cluster transcriptional repressor MraZ	-
A7326_RS03125	700822..701805	+	984	WP_088024273.1	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	-
A7326_RS03130	701802..702065	+	264	WP_005412242.1	cell division protein FtsL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (40-268)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (11-53)

Sequences

Toxin

Protein

• Length: 290 a.a.
• Molecular weight: 32542.53 Da
• Isoelectric Point: 8.2757

>T63243 WP_198360832.1 NZ_CP015612:c697404-696535 [Stenotrophomonas maltophilia]
MIPSPTPPHRVASIRQRLLDLARKRGEDFQFVLDRFAVERLLYRLSTSRYRNQFLLKGAMLFAVWFDAPHRPTRDADFLG
SGSAEPDRLLHIALSLCGMPGDDGLRFDPGSIVIEAIREEATYEGLRMRLIAHLGRARCHVQWDVGFGDAVITPPPEITY
PVILEGFPPACLRVYPRKTVFAEKLEAIAALGIANSRMKDFFDLLALIREDAMDRPHLVAAIGATFDRRRTPAPTPLPYG
LTQSFAADTQKQTQWRAFLRRNRLIAPDLSSVIAEIADYLDTLDTTVQS

Nucleotide

• Length: 870 bp

>T63243 NZ_CP015612:c697404-696535 [Stenotrophomonas maltophilia]
TTGATCCCCTCTCCAACACCTCCCCACCGCGTTGCTTCCATCCGGCAACGGCTGCTCGATCTCGCACGCAAGCGGGGGGA
GGACTTTCAGTTCGTGCTGGACAGGTTCGCCGTTGAGCGCCTGCTCTACCGGCTCTCCACTTCTCGATACCGCAACCAGT
TCCTGCTGAAGGGTGCCATGCTGTTCGCAGTGTGGTTCGACGCGCCGCACCGCCCTACACGGGATGCCGATTTCCTGGGA
TCCGGCAGCGCTGAGCCCGATCGCCTGCTACATATCGCACTTTCGCTCTGTGGAATGCCCGGGGACGACGGCCTGCGCTT
CGATCCAGGCAGCATCGTCATCGAGGCCATACGTGAAGAAGCCACGTACGAGGGGCTGCGCATGCGCCTGATCGCACATC
TGGGCCGCGCACGCTGCCATGTGCAGTGGGACGTCGGCTTTGGCGACGCGGTGATCACCCCGCCGCCGGAAATCACCTAT
CCGGTGATTCTGGAGGGATTCCCTCCAGCCTGCCTGCGCGTCTATCCACGCAAAACCGTGTTTGCCGAAAAGCTCGAGGC
TATAGCGGCACTGGGCATCGCTAACAGCAGGATGAAGGACTTCTTCGACTTGCTGGCACTGATCCGCGAAGACGCCATGG
ATCGCCCGCACCTTGTTGCGGCCATTGGCGCGACGTTTGATCGACGAAGGACCCCGGCGCCAACGCCCCTGCCCTACGGA
CTGACTCAGTCATTCGCCGCAGATACCCAGAAGCAGACCCAGTGGCGCGCCTTCCTGCGCAGGAATCGCCTGATCGCGCC
GGATCTTTCTTCGGTGATTGCCGAGATTGCCGACTATCTGGACACCCTCGACACAACCGTACAGTCCTGA

Antitoxin

Protein

• Length: 201 a.a.
• Molecular weight: 22232.96 Da
• Isoelectric Point: 11.2557

>AT63243 WP_088024269.1 NZ_CP015612:c698003-697401 [Stenotrophomonas maltophilia]
MGNAEAKARKLLRRAGTLRARELVTAGIARAQLTRLVEAGALIRLSRGVYALAERKSDDTDDGLRIIAERLPHPRLCLLS
ALRLHGLTTQAPFERWVSIGNSDRVPRIDWPPLRVVRMSATTLNAGLEERRVGGRLIYVSNAAKTVVDCFKFRNLVGLDV
ALEALRDALHSRATTPDALMEYARICRVARLMRPYLDALA

Nucleotide

• Length: 603 bp

>AT63243 NZ_CP015612:c698003-697401 [Stenotrophomonas maltophilia]
ATGGGAAACGCCGAGGCCAAGGCACGAAAGCTATTGCGACGCGCAGGCACCCTGCGCGCCCGCGAACTGGTGACTGCCGG
GATCGCCCGCGCCCAACTGACCCGCCTGGTCGAGGCAGGCGCACTGATCCGGTTGTCCCGTGGCGTCTACGCGTTGGCGG
AAAGAAAGAGCGACGACACCGATGATGGACTGCGGATCATTGCAGAACGCCTGCCACACCCCCGTCTGTGCCTGTTGAGT
GCCCTGCGCCTGCATGGCCTGACCACCCAGGCACCATTCGAACGCTGGGTTTCCATCGGCAACAGCGACCGCGTTCCGCG
GATCGACTGGCCGCCCCTCCGTGTGGTCCGCATGTCGGCAACGACCCTCAATGCGGGGCTGGAAGAACGTCGCGTAGGCG
GACGTCTCATATACGTCAGCAACGCAGCCAAAACCGTCGTCGATTGCTTCAAGTTCCGCAATCTCGTAGGGCTCGATGTC
GCACTTGAAGCCCTGCGTGACGCGCTTCACAGCCGTGCAACCACGCCGGATGCGTTGATGGAGTATGCGCGGATCTGCCG
CGTTGCCAGACTGATGAGACCGTACCTCGATGCCCTGGCTTGA