Detailed information of TA system TA063232

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 1208050..1208500
• Replicon: chromosome
• Accession: NZ_CP015600
• Organism: Pseudomonas antarctica strain PAMC 27494

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: A7J50_RS30400
• Protein ID: WP_082895828.1
• Coordinates: 1208228..1208500 (+)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A172YWJ3
• Locus tag: A7J50_RS05230
• Protein ID: WP_064450837.1
• Coordinates: 1208050..1208238 (+)
• Length: 63 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A7J50_RS05205	1203612..1204982	+	1371	WP_064450833.1	aromatic acid/H+ symport family MFS transporter	-
A7J50_RS05210	1205037..1205840	-	804	WP_064450834.1	tetratricopeptide repeat protein	-
A7J50_RS05215	1206028..1207047	+	1020	WP_064450835.1	Glu/Leu/Phe/Val dehydrogenase	-
A7J50_RS05220	1207103..1207363	-	261	WP_016974596.1	YebG family protein	-
A7J50_RS05225	1207637..1207897	+	261	WP_064450836.1	DUF3077 domain-containing protein	-
A7J50_RS05230	1208050..1208238	+	189	WP_064450837.1	hypothetical protein	Antitoxin
A7J50_RS30400	1208228..1208500	+	273	WP_082895828.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
A7J50_RS05235	1208666..1209154	+	489	WP_064450838.1	phosphate-starvation-inducible PsiE family protein	-
A7J50_RS05240	1209151..1209468	-	318	WP_064450839.1	DUF3509 domain-containing protein	-
A7J50_RS05245	1209768..1211054	-	1287	WP_064450840.1	HAAAP family serine/threonine permease	-
A7J50_RS05250	1211117..1212493	-	1377	WP_064450841.1	L-serine ammonia-lyase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10279.93 Da
• Isoelectric Point: 9.9280

>T63232 WP_082895828.1 NZ_CP015600:1208228-1208500 [Pseudomonas antarctica]
MLVEWAPAARAQLRQITDYISDRNPVAALELNQAIEACVLALSRRPHLYRPGRVVGTREMVVHPNYLVVYQVTDSIRVLS
VLHARQRYPS

Nucleotide

• Length: 273 bp

>T63232 NZ_CP015600:1208228-1208500 [Pseudomonas antarctica]
ATGCTGGTTGAGTGGGCCCCTGCAGCGCGGGCACAACTCCGGCAAATTACTGATTACATCAGCGACCGCAATCCAGTGGC
AGCGCTTGAGCTGAACCAGGCAATAGAAGCCTGTGTGCTGGCGCTATCTCGTAGACCCCACCTTTACCGCCCTGGACGTG
TCGTCGGCACGCGAGAAATGGTGGTGCATCCGAATTATCTGGTCGTCTATCAGGTGACCGACAGCATTCGGGTTCTCTCG
GTTTTACACGCACGCCAGCGATATCCTTCATAG

Antitoxin

Protein

• Length: 63 a.a.
• Molecular weight: 6856.54 Da
• Isoelectric Point: 4.3558

>AT63232 WP_064450837.1 NZ_CP015600:1208050-1208238 [Pseudomonas antarctica]
MDTSFSSGIPTDTEAQADSYDRWFRAKVQAALDDPSPGIPHDEVMAEMRELIESKRKKGDAG

Nucleotide

• Length: 189 bp

>AT63232 NZ_CP015600:1208050-1208238 [Pseudomonas antarctica]
ATGGACACTTCCTTTTCCTCAGGCATCCCAACAGATACCGAAGCGCAGGCCGACAGCTACGACCGCTGGTTTCGCGCCAA
AGTGCAAGCTGCTCTCGATGACCCAAGCCCAGGTATTCCTCATGATGAGGTGATGGCCGAGATGCGTGAGCTAATCGAAT
CCAAACGCAAGAAAGGCGATGCTGGTTGA

Structures

Antitoxin

• AlphaFold DB: A0A172YWJ3